Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Zhanju, Liu"'
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Background Monocytes and macrophages play an indispensable role in maintaining intestinal homeostasis and modulating mucosal immune responses in inflammatory bowel disease (IBD). Although numerous studies have described macrophage properties
Externí odkaz:
https://doaj.org/article/6bbf5ac073c84548aac0dcc556b1b121
Autor:
Han Gao, Kangsheng Peng, Yadi Shi, Shenshen Zhu, Ruicong Sun, Chunjin Xu, Ping Liu, Zhi Pang, Lanxiang Zhu, Weichang Chen, Baisui Feng, Huili Wu, Guangxi Zhou, Mingsong Li, Junxiang Li, Baijing Ding, Zhanju Liu, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 11, Pp 1316-1323 (2024)
Abstract. Background:. Histological healing is closely associated with improved long-term clinical outcomes and lowered relapses in patients with ulcerative colitis (UC). Here, we developed a novel diagnostic criterion for assessing histological heal
Externí odkaz:
https://doaj.org/article/4777087d2ae64da28bb9bb22ec9c3e98
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is a group of chronic immune-mediated gastrointestinal disorders. The etiology of IBD is multifactorial, involving genetic susceptibility, environmen
Externí odkaz:
https://doaj.org/article/c7507cf7ce1d4170995ae6cda585bdb0
Autor:
Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A. Flavell, Zhanju Liu, Mingsong Li, Wen Pan, Shu Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Epithelial barrier dysfunction and crypt destruction are hallmarks of inflammatory bowel disease (IBD). Intestinal stem cells (ISCs) residing in the crypts play a crucial role in the continuous self-renewal and rapid recovery of intestinal e
Externí odkaz:
https://doaj.org/article/e5a4e856daf14c8688835a13aa12fea9
Autor:
Dan Pu, Yao Yao, Chuan Zhou, Ruixian Liu, Zhihong Wang, Yan Liu, Dandan Wang, Binbin Wang, Yaohe Wang, Zhanju Liu, Zhe Zhang, Baisui Feng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Fecal microbiota transplantation (FMT) is currently a promising therapy for inflammatory bowel disease (IBD). However, clinical studies have shown that there is an obvious individual difference in the efficacy of FMT. Therefore, it is a pressing issu
Externí odkaz:
https://doaj.org/article/3e8d15f69ba540dbba165ffc531b5d73
Autor:
Han Zhang, Rahul Kalla, Jie Chen, Jianhui Zhao, Xuan Zhou, Alex Adams, Alexandra Noble, Nicholas T. Ventham, Judith Wellens, Gwo-Tzer Ho, Malcolm G. Dunlop, Jan Krzysztof Nowak, Yuan Ding, Zhanju Liu, Jack Satsangi, Evropi Theodoratou, Xue Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization study are first conducted to evaluate the association between smoking be
Externí odkaz:
https://doaj.org/article/04a74e10927f428d84730e560996c873
Autor:
Liang Chen, Dengfeng Kang, Leilei Fang, Mingming Sun, Mingsong Li, Guangxi Zhou, Chunjin Xu, Zhi Pang, Yulan Ye, Baisui Feng, Huili Wu, Jian Lin, Baijing Ding, Changqin Liu, Yanhong Shi, Zhanju Liu
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Anti-tumor necrosis factor (TNF) monoclonal antibodies, especially infliximab (IFX) and adalimumab (ADA), are considered the first-line treatment for active Crohn’s disease (CD). However, the predictive role of therapeutic drug monitori
Externí odkaz:
https://doaj.org/article/6f6f4821355e47e0817d25e0e5318203
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundUstekinumab (UST) is approved as an effective therapy for Crohn's disease (CD) in adults. Off-label use is increasing in the pediatric population, more data on safety and efficacy in pediatric patients with CD is urgently needed.AimsThis st
Externí odkaz:
https://doaj.org/article/046f0fcc12a84c769d3e70bd5fbafa57
Autor:
Jiewen Wang, Guangbo Kang, Huiying Lu, Ario deMarco, Haibin Yuan, Zelin Feng, Mengxue Gao, Xiaoli Wang, Huahong Wang, Xiaolan Zhang, Yuli Wang, Miao Zhang, Ping Wang, Yuanhang Feng, Zhanju Liu, Xiaocang Cao, He Huang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Background Inflammatory bowel diseases (IBDs) pose significant challenges in terms of treatment non‐response, necessitating the development of novel therapeutic approaches. Although biological medicines that target TNF‐α (tumour necrosi
Externí odkaz:
https://doaj.org/article/fa072c420d474d83b860711a021c74f5
Autor:
Gengfeng Li, Jian Lin, Xiang Gao, Huiling Su, Ritian Lin, Han Gao, Zhongsheng Feng, Huili Wu, Baisui Feng, Keqiang Zuo, Yingchuan Li, Wei Wu, Leilei Fang, Zhanju Liu
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTIntestinal epithelial cell (IEC) regulation of barrier function and mucosal homeostasis enables the establishment of a harmonious gut microenvironment. However, host-derived regulatory networks that modulate intestinal antimicrobial defenses
Externí odkaz:
https://doaj.org/article/b6d071b3a3144e2b808f120118e04a6e