Neuroprotective Effect of Sonic Hedgehog Mediated PI3K/AKT Pathway in Amyotrophic Lateral Sclerosis Model Mice

Autor: Yan Qi, Chen Yang, Hui Zhao, Zhanjin Deng, Jin Xu, Weijing Liang, Zhitang Sun, John Dirk Vestergaard Nieland

Publikováno v: Qi, Y, Yang, C, Zhao, H, Deng, Z, Xu, J, Liang, W, Sun, Z & Nieland, J D V 2022, ' Neuroprotective Effect of Sonic Hedgehog Mediated PI3K/AKT Pathway in Amyotrophic Lateral Sclerosis Model Mice ', Molecular Neurobiology, vol. 59, no. 11, pp. 6971-6982 . https://doi.org/10.1007/s12035-022-03013-z

Abstract The Sonic Hedgehog (SHH) signaling pathway is related to the progression of various tumors and nervous system diseases. Still, its specific role in neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), remains studied. Thi

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