Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Zhangyuan Pan"'
Autor:
Liu Yang, Hongwei Yin, Lijing Bai, Wenye Yao, Tan Tao, Qianyi Zhao, Yahui Gao, Jinyan Teng, Zhiting Xu, Qing Lin, Shuqi Diao, Zhangyuan Pan, Dailu Guan, Bingjie Li, Huaijun Zhou, Zhongyin Zhou, Fuping Zhao, Qishan Wang, Yuchun Pan, Zhe Zhang, Kui Li, Lingzhao Fang, George E. Liu
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-34 (2024)
Abstract Background Structural variations (SVs) have significant impacts on complex phenotypes by rearranging large amounts of DNA sequence. Results We present a comprehensive SV catalog based on the whole-genome sequence of 1060 pigs (Sus scrofa) re
Externí odkaz:
https://doaj.org/article/c40b6eea5fee49dcbf64d3676b9e71a6
Autor:
Pengju Zhao, Lihong Gu, Yahui Gao, Zhangyuan Pan, Lei Liu, Xingzheng Li, Huaijun Zhou, Dongyou Yu, Xinyan Han, Lichun Qian, George E. Liu, Lingzhao Fang, Zhengguang Wang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract Transposable elements (TEs) are a major source of genetic polymorphisms and play a role in chromatin architecture, gene regulatory networks, and genomic evolution. However, their functional role in pigs and contributions to complex traits ar
Externí odkaz:
https://doaj.org/article/7c7759a1217d4d5a9e79c45c52301a45
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7836 (2024)
Milk production is an important trait that influences the economic value of camels. However, the genetic regulatory mechanisms underlying milk production in camels have not yet been elucidated. We aimed to identify candidate molecular markers that af
Externí odkaz:
https://doaj.org/article/f777fe7ad6a7453c918bf32d78de1c96
Autor:
Guoqing Zhang, Mingxing Chu, Hao Yang, Hao Li, Jianxin Shi, Pingjie Feng, Shoufeng Wang, Zhangyuan Pan
Publikováno v:
Genes, Vol 15, Iss 3, p 376 (2024)
Sheep horns are composed of bone and sheaths, and the BMPR1A gene is required for cartilage and osteogenic differentiation. Therefore, the BMPR1A gene may have a function related to the sheep horn, but its relationship with the sheep horn remains unc
Externí odkaz:
https://doaj.org/article/a716cdffdef7424585564c1aea1b82a2
Autor:
Jinghui Li, Tianjing Zhao, Dailu Guan, Zhangyuan Pan, Zhonghao Bai, Jinyan Teng, Zhe Zhang, Zhili Zheng, Jian Zeng, Huaijun Zhou, Lingzhao Fang, Hao Cheng
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100390- (2023)
Summary: Assessment of genomic conservation between humans and pigs at the functional level can improve the potential of pigs as a human biomedical model. To address this, we developed a deep learning-based approach to learn the genomic conservation
Externí odkaz:
https://doaj.org/article/3b2a0a102f2e4142a70bc6d39d198e42
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionSuper-enhancers (SEs) are clusters of enhancers that act synergistically to drive the high-level expression of genes involved in cell identity and function. Although SEs have been extensively investigated in humans and mice, they have not
Externí odkaz:
https://doaj.org/article/a2c1d4dbbf2046fca459d7666a533980
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
In humans, variation of the ATP7A gene may cause cranial exostosis, which is similar to “human horn,” but the function of the ATP7A gene in sheep is still unknown. Tissue expression patterns and potential functional loci analysis of the ATP7A gen
Externí odkaz:
https://doaj.org/article/3f08aba3a6874a63affe846495a9ac17
Autor:
Yuelin Yao, Shuli Liu, Charley Xia, Yahui Gao, Zhangyuan Pan, Oriol Canela-Xandri, Ava Khamseh, Konrad Rawlik, Sheng Wang, Bingjie Li, Yi Zhang, Erola Pairo-Castineira, Kenton D’Mellow, Xiujin Li, Ze Yan, Cong-jun Li, Ying Yu, Shengli Zhang, Li Ma, John B. Cole, Pablo J. Ross, Huaijun Zhou, Chris Haley, George E. Liu, Lingzhao Fang, Albert Tenesa
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)
Abstract Background Cross-species comparison of transcriptomes is important for elucidating evolutionary molecular mechanisms underpinning phenotypic variation between and within species, yet to date it has been essentially limited to model organisms
Externí odkaz:
https://doaj.org/article/8e63f5a62bc44afea9ce80f059475d95
Autor:
Yiming Gong, Qiuju Chen, Xiaolong He, Xiangyu Wang, Xiaoyun He, Yunfei Wang, Zhangyuan Pan, Mingxing Chu, Ran Di
Publikováno v:
Animals, Vol 13, Iss 23, p 3639 (2023)
Previous studies have screened key candidate genes for litter size in sheep, including fibrillin-1 (FBN1), family with sequence similarity 184 member B (FAM184B) and zinc finger and AT-hook domain containing (ZFAT). Therefore, it is necessary to veri
Externí odkaz:
https://doaj.org/article/c0ea4651d0df4fe4a1387fdb553fa87c
Autor:
Marcela Maria de Souza, Simone Cristina Méo Niciura, Marina Ibelli Pereira Rocha, Zhangyuan Pan, Huaijun Zhou, Jennifer Jessica Bruscadin, Wellison Jarles da Silva Diniz, Juliana Afonso, Priscila Silva Neubern de Oliveira, Gerson B. Mourão, Adhemar Zerlotini, Luiz Lehmann Coutinho, James E. Koltes, Luciana Correia de Almeida Regitano
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-16 (2022)
Abstract Background Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying this trait may help improve the accuracy of breeding programs. However, little is known about epig
Externí odkaz:
https://doaj.org/article/d9a0fde4ef134748abd5451d9672dc27