Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zhangyi Liang"'
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004042 (2014)
Crossing-over is a central feature of meiosis. Meiotic crossover (CO) sites are spatially patterned along chromosomes. CO-designation at one position disfavors subsequent CO-designation(s) nearby, as described by the classical phenomenon of CO interf
Externí odkaz:
https://doaj.org/article/0e1ba47b67014841b915fc9c40dd01bd
Autor:
Fei Liu, Kangmin He, Xinxing Yang, Ning Xu, Zhangyi Liang, Ming Xu, Xinsheng Zhao, Qide Han, Youyi Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21520 (2011)
G protein-coupled receptors (GPCRs) activate mitogen-activated protein kinases through a number of distinct pathways in cells. Increasing evidence has suggested that endosomal signaling has an important role in receptor signal transduction. Here we i
Externí odkaz:
https://doaj.org/article/32a46c57d8824fdeb0b93dc3199ec5ae
Autor:
Lingluo Chu, Jay K. Fisher, Zhangyi Liang, Nancy Kleckner, Maria V. Mukhina, John W. Hutchinson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Spatial patterns are a prominent and interesting feature of both biological and physical systems. We have discovered that mammalian mitotic chromosomes, which comprise two closely associated sister chromatids, exhibit two interesting spa
Autor:
Denise Zickler, Lingluo Chu, Nancy Kleckner, Zhangyi Liang, John W. Hutchinson, Maria V. Mukhina, Jay K. Fisher, Zheng Zhang, Nadine Vincenten
Publikováno v:
Mol Cell
Molecular Cell
Molecular Cell, 2020, ⟨10.1016/j.molcel.2020.07.002⟩
Molecular Cell
Molecular Cell, 2020, ⟨10.1016/j.molcel.2020.07.002⟩
A long-standing conundrum is how mitotic chromosomes can compact, as required for clean separation to daughter cells, while maintaining close parallel alignment of sister chromatids. Pursuit of this question, by high resolution 3D fluorescence imagin
Autor:
Kazuhiro Maeshima, Denise Zickler, Nancy Kleckner, Frederick S. Chang, Mara Prentiss, Guillaume Witz, Zhangyi Liang
Publikováno v:
Cell
Cell, Elsevier, 2015, 161 (5), pp.1124-37
Cell, 2015, 161 (5), pp.1124-37
Cell, Elsevier, 2015, 161 (5), pp.1124-37
Cell, 2015, 161 (5), pp.1124-37
International audience; Mammalian mitotic chromosome morphogenesis was analyzed by 4D live-cell and snapshot deconvolution fluorescence imaging. Prophase chromosomes, whose organization was previously unknown, are revealed to comprise co-oriented sis
Publikováno v:
Biophysical Chemistry. 154:56-65
The nonprocessive kinesin-14 Ncd motor binds to microtubules and hydrolyzes ATP, undergoing a single displacement before releasing the microtubule. A lever-like rotation of the coiled-coil stalk is thought to drive Ncd displacements or steps along mi
Publikováno v:
Current Biology. 19(2):163-168
SummaryNew information has been obtained recently regarding microtubule organization in Xenopus extract spindles. These spindles assemble in vitro by chromatin-mediated microtubule nucleation [1] and consist of randomly interspersed long and short mi
Publikováno v:
Journal of Cell Science. 121:3834-3841
The Ncd kinesin-14 motor is required for meiotic spindle assembly in Drosophila oocytes and produces force in mitotic spindles that opposes other motors. Despite extensive studies, the way the motor binds to the spindle to perform its functions is no
Publikováno v:
Chinese Journal of Chemical Physics. 20:445-448
The transport of internalized 1A-adrenergic receptor (1A-AR) by myosin protein in live cells was studied. The technique of single particle tracking by fluorescence imaging with high temporal and spatial resolution was used. The endosomes of 1A-AR wer
Autor:
Zhi Zhen Lu, You Yi Zhang, Zhangyi Liang, Ming Xu, Ning Xu, Ying Hua Guan, Xin Sheng Zhao, Qi De Han
Publikováno v:
Solid State Phenomena. :771-776
AIM: The present study aims at investigating dynamic behaviors of a 1B -adrenergic receptor (a 1B -AR) at molecular level in living cells. METHODS: Wide-field imaging was applied on the detection of real-time dynamic behaviors of a 1B -AR using fluor