Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Zhangting, Wang"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Gonad development includes sex determination and divergent maturation of the testes and ovaries. Recent advances in measuring gene expression in single cells are providing new insights into this complex process. However, the underlying epige
Externí odkaz:
https://doaj.org/article/d05caea8691042928d918408755731b5
Autor:
Huanhuan Jia, Meili Chen, Yanzhen Cai, Xiaoling Luo, Gang Hou, Yongfeng Li, Chunmei Cai, Jun Chen, Qingnan Li, Kai-Kei Miu, Sin-Hang Fung, Zhangting Wang, Ren Huang, Huiyong Shen, Li Lu
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Background Ankylosing spondylitis is a progressive, disabling joint disease that affects millions worldwide. Given its unclear etiology, studies of ankylosing spondylitis relied heavily on drug-induced or transgenic rodent models which retai
Externí odkaz:
https://doaj.org/article/a80ce1294a9e4d07a1fb0c6c4ae35658
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
DNA methylation and hydroxymethylation have been implicated in the regulatory dynamics of gene expression in normal development and differentiation. 5-Hydroxymethylcytosine (5hmC), created by the ten-eleven translocation (TET) protein-catalyzed oxida
Externí odkaz:
https://doaj.org/article/0823d2e6df08430a9c9a0b257908d4d3
Autor:
Zhangting Wang, Sin-Hang Fung, Chi-Lam Yu, Patrick Wai-Nok Law, Suyu Hao, Kai-Kei Miu, Wai-Yee Chan
Publikováno v:
Re:GEN Open, Vol 1, Iss 1, Pp 117-129 (2021)
Background: MicroRNAs (miRNAs) are an emerging class of non-coding endogenous RNAs that participated in multiple cellular processes, including cell differentiation, proliferation and signaling/signal transduction. We would like to scrutinize the cont
Externí odkaz:
https://doaj.org/article/eeb78b076ba54225adb6f8c10e90cd92
Autor:
Zhangting Wang, Jiang Ma, Sheng Yao, Yisheng He, Kai-Kei Miu, Qingsu Xia, Peter P. Fu, Yang Ye, Ge Lin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Misuse of pyrrolizidine alkaloid (PA)-containing plants or consumption of PA-contaminated foodstuffs causes numerous poisoning cases in humans yearly, while effective therapeutic strategies are still limited. PA-induced liver injury was initiated by
Externí odkaz:
https://doaj.org/article/074b6d58bfd146fb82eda3d21f6688cd
A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA
Autor:
Li Lu, Yanzhen Cai, Xiaoling Luo, Zhangting Wang, Sin Hang Fung, Huanhuan Jia, Chi Lam Yu, Wai Yee Chan, Kai Kei Miu, Wende Xiao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Iatrogenic glucocorticoid (GC)-induced osteoporosis (GIO) is an idiosyncratic form of secondary osteoporosis. Genetic predisposition among individuals may give rise to variant degree of phenotypic changes but there has yet been a documented unified p
Externí odkaz:
https://doaj.org/article/6d2c8ea5b86f45f8b7047596e82833d9
Autor:
Paul Lee, Rita Yim, Kai-Kei Miu, Sin-Hang Fung, Jason Jinyue Liao, Zhangting Wang, Jun Li, Yammy Yung, Hiu-Tung Chu, Pui-Kwan Yip, Emily Lee, Eric Tse, Yok-Lam Kwong, Harinder Gill
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5670 (2022)
In myelodysplastic syndrome (MDS), resistance to hypomethylating agents (HMA) portends a poor prognosis, underscoring the importance of understanding the molecular mechanisms leading to HMA-resistance. In this study, P39 and Kasumi-1 cells and their
Externí odkaz:
https://doaj.org/article/242f13a9adea43ac815fe4e8db79d843
Autor:
Zhangting Wang, Kai-Kei Miu, Xueyan Zhang, Angel Tsz-Yau Wan, Gang Lu, Hoi-Hung Cheung, Heung-Man Lee, Alice Pik-Shan Kong, Juliana Chung-Ngor Chan, Wai-Yee Chan
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100179- (2020)
Background & Aims: The paradox of hepatic insulin resistance describes the inability for liver to respond to bioenergetics hormones in suppressing gluconeogenesis whilst maintaining lipid synthesis. Here, we report the deficiency of miR-192-3p in the
Externí odkaz:
https://doaj.org/article/73b0b1e43800418cbc94f8979a3a4eaa
Autor:
Paul Lee, Rita Yim, Sin-Hang Fung, Kai-Kei Miu, Zhangting Wang, Ka-Chun Wu, Lester Au, Garret Man-Kit Leung, Victor Ho-Fun Lee, Harinder Gill
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4647 (2022)
Myelodysplastic syndrome (MDS) is a clonal myeloid neoplasm characterized by ineffective hematopoiesis, cytopenia, dysplasia, and clonal instability, leading to leukemic transformation. Hypomethylating agents are the mainstay of treatment in higher-r
Externí odkaz:
https://doaj.org/article/87e11914ef9747cb8f7dc97cc0553dc2
Publikováno v:
Human Reproductive and Prenatal Genetics ISBN: 9780323913805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a3f3902780daea752a68697108548f
https://doi.org/10.1016/b978-0-323-91380-5.00016-2
https://doi.org/10.1016/b978-0-323-91380-5.00016-2