Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zhangsen Zhou"'
Autor:
Yewei Ji, Yuan Luo, Yating Wu, Yao Sun, Lianfeng Zhao, Zhen Xue, Mengqi Sun, Xiaoqiong Wei, Zinan He, Shuangcheng Alivia Wu, Liangguang Leo Lin, You Lu, Lei Chang, Fei Chen, Siyu Chen, Wei Qian, Xiaoxi Xu, Shengnuo Chen, Dongli Pan, Zhangsen Zhou, Sheng Xia, Chih-Chi Andrew Hu, Tingbo Liang, Ling Qi
Publikováno v:
Nature Cell Biology. 25:726-739
Stimulator of interferon genes (STING) orchestrates the production of proinflammatory cytokines in response to cytosolic double-stranded DNA; however, the pathophysiological significance and molecular mechanism underlying the folding and maturation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8fd1b5f445c8b6f44fe879d08eeead9
https://doi.org/10.1038/s41556-023-01138-4
https://doi.org/10.1038/s41556-023-01138-4
Autor:
Zhangsen Zhou, Torres, Mauricio, Sha, Haibo, Halbrook, Christopher J., Van den Bergh, Françoise, Reinert, Rachel B., Tatsuya Yamada, Siwen Wang, Yingying Luo, Hunter, Allen H., Chunqing Wang, Sanderson, Thomas H., Liu, Meilian, Taylor, Aaron, Hiromi Sesaki, Lyssiotis, Costas A., Jun Wu, Kersten, Sander, Beard, Daniel A., Ling Qi lingq@med.umich.edu
Publikováno v:
Science. 4/3/2020, Vol. 367 Issue 6486, p54-60. 7p. 1 Color Photograph, 5 Graphs.
Autor:
Mauricio Torres, Yang Zhang, Liangguang Lin, Wenyue Zheng, Yi Xiong, Ling Qi, Rajasree Menon, Jeffrey B. Hodgin, Rui Hua, Shengyi Sun, Puneet Garg, Christopher L. O’Connor, Xiaoqiong Wei, Chih-Chi Andrew Hu, Markus Bitzer, Gensheng Zhang, Xiaoxi Xu, Ming Liu, Sei Yoshida, Zhangsen Zhou, Rakesh Verma, Hiroyuki Mori, Edgar A. Otto, Chih-Hang Anthony Tang
Publikováno v:
J Clin Invest
Podocytes are key to the glomerular filtration barrier by forming a slit diaphragm between interdigitating foot processes; however, the molecular details and functional importance of protein folding and degradation in the ER remain unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0924abf7c424ff1f7f3832ec76d3fe
https://europepmc.org/articles/PMC8011890/
https://europepmc.org/articles/PMC8011890/
Publikováno v:
Diabetes. 69
Heat generation, mediated by mitochondrial respiration in Brown Adipose Tissue (BAT), is important for defense against cold and maintenance of whole-body homeostasis. Recent works have demonstrated the presence of metabolically active BAT in adult hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f45a93bc550afc1e8032ee220bce0f6
https://doi.org/10.2337/db20-1959-p
https://doi.org/10.2337/db20-1959-p
Autor:
Chunqing Wang, Ling Qi, Allen H. Hunter, Tatsuya Yamada, Daniel A. Beard, Hiromi Sesaki, Aaron Taylor, Mauricio Torres, Yingying Luo, Siwen Wang, Christopher J. Halbrook, Françoise Van den Bergh, Costas A. Lyssiotis, Meilian Liu, Haibo Sha, Sander Kersten, Zhangsen Zhou, Rachel B. Reinert, Thomas H. Sanderson, Jun Wu
Publikováno v:
Science 368 (2020) 6486
Science
Science, 368(6486), 54-60
Science (New York, N.Y.), vol 368, iss 6486
Science
Science, 368(6486), 54-60
Science (New York, N.Y.), vol 368, iss 6486
Organelle cross-talk Endoplasmic reticulum (ER)–associated degradation (ERAD) is a quality control mechanism that allows for targeted degradation of proteins in the ER. Zhou et al. found that a particular protein complex in ERAD, Sel1L-Hrd1, regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd217724f863398d9a8c426b358cc6b7
https://research.wur.nl/en/publications/endoplasmic-reticulum-associated-degradation-regulates-mitochondr
https://research.wur.nl/en/publications/endoplasmic-reticulum-associated-degradation-regulates-mitochondr
Autor:
Xiongjie Shi, Zhangsen Zhou, Mei-Xin Li, Huabin Zhao, Wei Qi, Bao-Liang Song, Jie Liu, Liping Chu, Jie Luo, Jingrong Liu, Jing-Ming Xia, Hengwu Jiao
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Insig-2 is an ER membrane protein negatively controlling lipid biosynthesis. Here, we find that Insig-2 is increased in the tissues, including liver, but unaltered in the muscle of gp78-deficient mice. In hepatocytes and undifferentiated C2C12 myobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3184544df35f8385fe3168769214bfe2
http://europepmc.org/articles/PMC6969111
http://europepmc.org/articles/PMC6969111
Publikováno v:
Diabetes. 68
Recent studies have implicated the endoplasmic reticulum (ER) in organelle crosstalk including mitochondria; however, the underlying molecular mechanism and physiological significance remain largely unclear. Here we show that the Sel1L-Hrd1 protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f37dea914b282889222a8fca49f7ef
https://doi.org/10.2337/db19-141-or
https://doi.org/10.2337/db19-141-or
Autor:
Yang Shen, Bo-Liang Li, Jie Luo, Na Li, Bao-Liang Song, Zhangsen Zhou, Ying Xiong, Hong-Hua Miao, Feng Xu, Jie Xu
Publikováno v:
Hepatology (Baltimore, Md.). 65(6)
Obesity is a critical risk factor for hepatocellular carcinoma (HCC). However, it remains unknown whether inhibition of de novo lipid biosynthesis can suppress HCC. In this study, we blocked the sterol regulatory element-binding protein (SREBP) pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1171a18cb8aca9b8539a0c297688b83
https://pubmed.ncbi.nlm.nih.gov/28027595
https://pubmed.ncbi.nlm.nih.gov/28027595
Autor:
Sei Yoshida1,2 seiyoshi@nankai.edu.cn, Xiaoqiong Wei1, Gensheng Zhang1, O'Connor, Christopher L.3, Torres, Mauricio1, Zhangsen Zhou1, Liangguang Lin1, Menon, Rajasree3, Xiaoxi Xu4, Wenyue Zheng2, Yi Xiong5, Otto, Edgar A.3, Chih-Hang Anthony Tang6, Rui Hua2, Verma, Rakesh3, Hiroyuki Mori1, Yang Zhang7, Chih-Chi Andrew Hu6, Ming Liu4, Garg, Puneet3
Publikováno v:
Journal of Clinical Investigation. 4/1/2021, Vol. 131 Issue 7, p1-16. 16p.