Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Zhangqiang Li"'
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
Voltage-gated sodium (Nav) channels govern membrane excitability by initiating and propagating action potentials. Consistent with their physiological significance, dysfunction, or mutations in these channels are associated with various channelopathie
Externí odkaz:
https://doaj.org/article/5652f4a817e64dfeb2bfebf45b42f072
Publikováno v:
Small Science, Vol 3, Iss 12, Pp n/a-n/a (2023)
Nanoscience and technology have made significant achievements in the past few decades. Quantum‐sized materials, as a key component of nanomaterials, have attracted increasing interest due to their unique structures and extremely reduced sizes. Such
Externí odkaz:
https://doaj.org/article/49f24c35389a405ea6f3296671514ff7
Publikováno v:
Nano Research. 16:5803-5808
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/27/2024, Vol. 121 Issue 9, p1-8, 17p
Quantum-sized topological insulators/semimetals enable ultrahigh and broadband saturable absorption.
Publikováno v:
Nanoscale Horizons; Dec2023, Vol. 8 Issue 12, p1686-1694, 9p
Autor:
Gaoxingyu, Huang, Qiurong, Wu, Zhangqiang, Li, Xueqin, Jin, Xiaoshuang, Huang, Tong, Wu, Xiaojing, Pan, Nieng, Yan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
Voltage-gated sodium (Na
Autor:
Xiaoshuang, Huang, Xueqin, Jin, Gaoxingyu, Huang, Jian, Huang, Tong, Wu, Zhangqiang, Li, Jiaofeng, Chen, Fang, Kong, Xiaojing, Pan, Nieng, Yan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(30)
The dorsal root ganglia-localized voltage-gated sodium (Na
Autor:
Nieng Yan, Jianlin Lei, Zhangqiang Li, Gaoxingyu Huang, Xiaojing Pan, Tong Wu, Kun Wu, Xueqin Jin
Publikováno v:
Angewandte Chemie. 133:11575-11581
Na v 1.5, the primary voltage-gated Na + (Na v ) channel in heart, is a major target for class I antiarrhythmic agents. Here we present the cryo-EM structure of full-length human Na v 1.5 bound to quinidine, a class Ia antiarrhythmic drug, at 3.3 A r
Publikováno v:
Nano Today. 46:101592
Autor:
Nieng Yan, Huaizong Shen, Xiaojing Pan, Jianlin Lei, Zhangqiang Li, Gaoxingyu Huang, Shuai Gao, Lei Liu, Xiaoshuang Huang
Publikováno v:
Science. 363:1309-1313
Targeting sodium channels Voltage-gated sodium (Na v ) channels have been implicated in cardiac and neurological disorders. There are many subtypes of these channels, making it challenging to develop specific therapeutics. A core α subunit is suffic