Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zhangjin Shen"'
Autor:
Fang Zheng, Jiamin Zhong, Kelie Chen, Yu Shi, Fang Wang, Shengchao Wang, Song Tang, Xiaoyu Yuan, Zhangjin Shen, Sangsang Tang, Dajing Xia, Yihua Wu, Weiguo Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background Ovarian cancer is commonly associated with a poor prognosis due to metastasis and chemoresistance. PINK1 (PTEN-induced kinase 1) is a serine/threonine kinase that plays a crucial part in regulating various physiological and pathop
Externí odkaz:
https://doaj.org/article/16cde446b6a34c42b1903a7c67b2df9d
CircSLC39A8 attenuates paclitaxel resistance in ovarian cancer by regulating the miR‑185‑5p/BMF axis
Autor:
Yuwan Liu, Zhangjin Shen, Xinyi Wei, Lingkai Gu, Mengxia Zheng, Yanan Zhang, Xiaodong Cheng, Yunfeng Fu, Weiguo Lu
Publikováno v:
Translational Oncology, Vol 36, Iss , Pp 101746- (2023)
Chemoresistance to paclitaxel (PTX) is one of the main reasons for treatment failure and poor prognosis in patients with advanced ovarian cancer. Therefore, it is imperative to explore the mechanisms related to chemotherapy resistance in ovarian canc
Externí odkaz:
https://doaj.org/article/3373f4b3b44d4bc4a5a64d786584c3fa
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-14 (2022)
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors are efficacious in treating platinum-sensitive ovarian cancer (OC), but demonstrate limited efficiency in patients with platinum-resistant OC. Thus, further investigations into combined strategi
Externí odkaz:
https://doaj.org/article/7d21a15fc0d747189920e26c5a19a03b
Autor:
Shizhen Shen, Zhangjin Shen, Conghui Wang, Xiaodong Wu, Lingfang Wang, Lele Ye, Songfa Zhang, Xiaodong Cheng
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106521- (2023)
Summary: Small extracellular vesicles (sEVs) and large extracellular vesicles (lEVs), play vital roles in intercellular communication. We optimized a method that extracts EVs from epithelial ovarian cancer (EOC) tissues for the purpose of investigati
Externí odkaz:
https://doaj.org/article/535c68e695db483e91b98f9398be8824
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Background: Patients with late-stage ovarian cancer still have a very poor prognosis due to chemotherapy resistance. Curcumin has been shown to synergistically enhance the therapeutic effects of multiple chemotherapeutic agents, but the potential inv
Externí odkaz:
https://doaj.org/article/386ae772d02b47d9bf33b04a4941ff7e
Autor:
Lingfang Wang, Jian Zhang, Yingfeng Su, Yasen Maimaitiyiming, Siqi Yang, Zhangjin Shen, Shitong Lin, Shizhen Shen, Guankai Zhan, Fenfen Wang, Chih-Hung Hsu, Xiaodong Cheng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
RNA methylation has recently emerged as an important category of epigenetic modifications, which plays diverse physiopathological roles in various cancers. Recent studies have confirmed the presence of 5-methylcytosine (m5C) modification on mammalian
Externí odkaz:
https://doaj.org/article/3b06e21bd1f74338bbdb03469d8e1c79
Autor:
Jiaying Wang, Conghui Wang, Yang Li, Mingyue Li, Tingjia Zhu, Zhangjin Shen, Hui Wang, Weiguo Lv, Xinyu Wang, Xiaodong Cheng, Xing Xie
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 5, Pp n/a-n/a (2021)
Abstract Introduction Exosomal microRNA (miRNA) as a mediator of intercellular communication plays an essential part in tumor‐relevant angiogenesis. Therapy against angiogenesis has been demonstrated to have a remarkable antitumor efficacy in vario
Externí odkaz:
https://doaj.org/article/5efe84cc240747c9886c251ad0c98935
Autor:
Kelie Chen, Xiaoyu Yuan, Shengchao Wang, Fang Zheng, Zhiqin Fu, Zhangjin Shen, Xiaodong Cheng, Yuwei Wang, Song Tang, Heng Ni, Fang Wang, Guang Lu, Yihua Wu, Dajing Xia, Weiguo Lu
Publikováno v:
Oncogene. 42:1438-1452
Peritoneal metastasis is a key feature of advanced ovarian cancer, but the critical protein required for ovarian cancer metastasis and progression is yet to be defined. Thus, an unbiased high throughput and in-depth study is warranted to unmask the m
Autor:
Zhangjin Shen, Lingkai Gu, Yuwan Liu, Lingfang Wang, Jiawei Zhu, Sangsang Tang, Xinyi Wei, Jiaying Wang, Songfa Zhang, Xinyu Wang, Xiaodong Cheng, Xing Xie, Weiguo Lu
Publikováno v:
Oncogene. 41:4145-4158
Wide metastasis contributes to a high death rate in ovarian cancer, and understanding of the molecular mechanism helps to find effective targets for metastatic ovarian cancer therapy. It has been found that phospholipase A2-activating protein (PLAA)
Autor:
Xinyi Wei, Conghui Wang, Sangsang Tang, Qian Yang, Zhangjin Shen, Jiawei Zhu, Xiaodong Cheng, Xinyu Wang, Xing Xie, Junfen Xu, Weiguo Lu
Background Ovarian cancer (OC) has the highest fatality rate amongst all gynecologic malignancies. Exploring new factors and pathways associated with development of ovarian cancer would help to identify new therapeutic targets. Long non-coding RNAs (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfeaa961d842a47a570f91e180eec347
https://doi.org/10.21203/rs.3.rs-1333435/v1
https://doi.org/10.21203/rs.3.rs-1333435/v1