Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zhanghong Xiao"'
Autor:
Yanjuan Huang, Zilin Guan, Xiuling Dai, Yifeng Shen, Qin Wei, Lingling Ren, Jingwen Jiang, Zhanghong Xiao, Yali Jiang, Di Liu, Zeqian Huang, Xiaoyu Xu, Yong Luo, Chunshun Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Bone metastases are associated with poor prognosis in patients with breast cancer and limited therapeutic options. Here the authors exploit near-infrared light responsive macrophages for the tumor-selective delivery of oxaliplatin prodrug for chemo-p
Externí odkaz:
https://doaj.org/article/6612050fe360461b84661984dadfcace
Autor:
Yanjuan Huang, Zhanghong Xiao, Zilin Guan, Zishan Zeng, Yifeng Shen, Xiaoyu Xu, Chunshun Zhao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2384-2403 (2020)
The “vicious cycle” established between tumor growth and osteolysis aggravates the process of breast cancer bone metastasis, leading to life-threatening skeletal-related events that severely reduce survival and quality of life. To effectively int
Externí odkaz:
https://doaj.org/article/31a80dbe3f834c2c93082bcad00fd8b7
Autor:
Lidong, Ding1 (AUTHOR), Zhanghong, Xiao1 (AUTHOR), Huawu, Mao1 (AUTHOR), Xiaofang, Hang1 (AUTHOR), Junhua, Guo1 (AUTHOR), Kaifu, Ke2 (AUTHOR), Jue, Chen3 (AUTHOR)
Publikováno v:
Neurology India. Jan/Feb2021, Vol. 69 Issue 1, p75-80. 6p.
Autor:
Zhanghong Xiao, Zilin Guan, Chunshun Zhao, Zishan Zeng, Yifeng Shen, Yanjuan Huang, Xiaoyu Xu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2384-2403 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The “vicious cycle” established between tumor growth and osteolysis aggravates the process of breast cancer bone metastasis, leading to life-threatening skeletal-related events that severely reduce survival and quality of life. To effectively int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc1625135ff1f5b2307aced9886b9f3
https://doi.org/10.1016/j.apsb.2020.06.006
https://doi.org/10.1016/j.apsb.2020.06.006
Autor:
Zilin Guan, Yali Jiang, Yifeng Shen, Yanjuan Huang, Xiaoyu Xu, Chunshun Zhao, Zhanghong Xiao, Zeqian Huang
Publikováno v:
Journal of Controlled Release. 319:119-134
Current therapeutic strategies for the treatment of bone metastases are often limited by the lack of selectivity, severe systemic toxicity and suboptimal efficacy. Nanomedicine meditated chemo-photodynamic therapy provides a promising therapeutic opp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b45b24664402b80aa06c866273a688
https://doi.org/10.1016/j.jconrel.2019.12.043
https://doi.org/10.1016/j.jconrel.2019.12.043
Autor:
Meng Xia, Tao Zhang, Meixu Chen, Congjun Xu, Chunshun Zhao, Zilin Guan, Yuqi Gao, Zhanghong Xiao, Hualu Lai, Yuanfeng He, Jing Wang, Lingling Ren
Publikováno v:
Journal of medicinal chemistry. 64(18)
Potent and selective ferroptosis regulators promote an intensive understanding of the regulation and mechanisms underlying ferroptosis, which is highly associated with various diseases. In this study, through a stepwise structure optimization, a pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0e8184862fa1dfcd7cc2657a10dd25
https://pubmed.ncbi.nlm.nih.gov/34506134
https://pubmed.ncbi.nlm.nih.gov/34506134
Autor:
Lingling Ren, Yong Luo, Qin Wei, Zilin Guan, Zhanghong Xiao, Zeqian Huang, Jingwen Jiang, Yifeng Shen, Di Liu, Yali Jiang, Chunshun Zhao, Xiuling Dai, Yanjuan Huang, Xiaoyu Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications
Nature Communications
Patients with primary and bone metastatic breast cancer have significantly reduced survival and life quality. Due to the poor drug delivery efficiency of anti-metastasis therapy and the limited response rate of immunotherapy for breast cancer, effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaa54c4a9314292db65bab229e5899d
https://doi.org/10.1038/s41467-021-24564-0
https://doi.org/10.1038/s41467-021-24564-0
Autor:
Chunshun Zhao, Haolan Yang, Yanjuan Huang, Hualu Lai, Zeqian Huang, Congjun Xu, Jie Chen, Zilin Guan, Zhanghong Xiao, Xiaoyu Xu, Tao Zhang
Publikováno v:
International journal of pharmaceutics. 603
The pentose phosphate pathway (PPP) plays a critical role by providing ribulose-5-phosphate (Ru5P) and NADPH for nucleotide synthesis and reduction energy, respectively. Accordingly, blocking the PPP process may be an effective strategy for enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a497e25b3a939cf71f1b45bb4885a3ae
https://pubmed.ncbi.nlm.nih.gov/33961957
https://pubmed.ncbi.nlm.nih.gov/33961957
Autor:
Chunshun Zhao, Congjun Xu, Yifeng Shen, Gaofei Wei, Yanjuan Huang, Xiaoyu Xu, Yali Jiang, Zhanghong Xiao, Liangfeng Huang
Publikováno v:
Chemical Engineering Journal. 380:122369
Strategies utilizing reactive oxygen species (ROS) to cause cell death are widely practiced for cancer therapy, including photodynamic therapy (PDT) and chemodynamic therapy (CDT). However, the efficiency of PDT alone is greatly hindered by tumor hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a03d1c0e8a9753a9c4fcea06644dbef0
https://doi.org/10.1016/j.cej.2019.122369
https://doi.org/10.1016/j.cej.2019.122369