Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Zhangfu Li"'
Autor:
Zhangfu Li, Jiangbei Yuan, Qingen Da, Zilong Yan, Jianhua Qu, Dan Li, Xu Liu, Qimin Zhan, Jikui Liu, Jing Ni
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 19, Pp 2351-2361 (2023)
Abstract. Background:. Long non-coding RNA colon cancer-associated transcript 1 (CCAT1) is involved in transforming multiple cancers into malignant cancer types. Previous studies underlining the mechanisms of the functions of CCAT1 primarily focused
Externí odkaz:
https://doaj.org/article/ee2bd219169644349b8af2673bc27a82
Autor:
Hongnan Mo, Xuefeng Liu, Yu Xue, Hongyan Chen, Shichao Guo, Zhangfu Li, Shuang Wang, Caiming Li, Jiashu Han, Ming Fu, Yongmei Song, Dan Li, Fei Ma
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background CDK4/6 inhibitors combined with endocrine therapy has become the preferred treatment approach for patients with estrogen receptor-positive metastatic breast cancer. However, the predictive biomarkers and mechanisms of innate resis
Externí odkaz:
https://doaj.org/article/e116ef9a09024d378290ec5982810b3b
Autor:
Yongsheng Huang, Sijia Liu, Mengjie Shan, Sophie C. Hagenaars, Wilma E. Mesker, Danielle Cohen, Lin Wang, Zhi Zheng, Peter Devilee, Rob A. E. M. Tollenaar, Zhangfu Li, Yongmei Song, Long Zhang, Dan Li, Peter ten Dijke
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Transforming growth factor-β (TGF-β) acts as a pro-metastatic factor in advanced breast cancer. RNF12, an E3 ubiquitin ligase, stimulates TGF-β signaling by binding to the inhibitory SMAD7 and inducing its proteasomal degradation. How RNF
Externí odkaz:
https://doaj.org/article/3fd5a6d714d349f3ac03fb9c0b86f952
Publikováno v:
Mediators of Inflammation, Vol 2023 (2023)
Intervertebral disc degeneration (IDD) is a major contributor to back, neck, and radicular pain. It is related to changes in tissue structure and function, including the breakdown of the extracellular matrix (ECM), aging, apoptosis of the nucleus pul
Externí odkaz:
https://doaj.org/article/3af0c2667b8c443ebcf74a4440ccdd27
Autor:
Wenchang Xiao, Danna Yeerken, Jia Li, Zhangfu Li, Lanfang Jiang, Dan Li, Ming Fu, Liying Ma, Yongmei Song, Weimin Zhang, Qimin Zhan
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Autophagy is the main degradation pathway to eliminate long-lived and aggregated proteins, aged or malfunctioning organelles, which is essential for the intracellular homeostasis and prevention of malignant transformation. Although the proce
Externí odkaz:
https://doaj.org/article/27f5350bf8014170b6ad52395220756b
Autor:
Zilong Yan, Qingen Da, Zhangfu Li, Qirui Lin, Jing Yi, Yanze Su, Guanyin Yu, Qingqi Ren, Xu Liu, Zewei Lin, Jianhua Qu, Weihua Yin, Jikui Liu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
NIMA-related kinase 7 (NEK7) is a serine/threonine kinase involved in cell cycle progression via mitotic spindle formation and cytokinesis. It has been related to multiple cancers, including breast cancer, hepatocellular cancer, lung cancer, and colo
Externí odkaz:
https://doaj.org/article/2d95ca608a39473d9fb665766a8e6f19
Autor:
Zilong Yan, Jianhua Qu, Zhangfu Li, Jing Yi, Yanze Su, Qirui Lin, Guangyin Yu, Zewei Lin, Weihua Yin, Fengmin Lu, Jikui Liu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The prognosis for pancreatic ductal adenocarcinoma (PDAC) patients is still dismal. Elucidation of associated genomic alteration may provide effective therapeutic strategies for PDAC treatment. NIMA-related protein kinase 7 is widely expressed in var
Externí odkaz:
https://doaj.org/article/691fe003ac754a598547f68c34562408
Autor:
Guangchao Wang, Shichao Guo, Weimin Zhang, Zhangfu Li, Jiancheng Xu, Dan Li, Yan Wang, Qimin Zhan
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Esophageal squamous cell cancer (ESCC) is a common malignancy with a poor 5-year overall survival in China. Altered DNA damage repair (DDR) pathways are associated with a predisposition to cancer and contribute to therapeutic response and resistance
Externí odkaz:
https://doaj.org/article/9bb2282d5bea4ef6b6105b9c7d99e1e3
Publikováno v:
PeerJ, Vol 7, p e7946 (2019)
Background Heat shock protein 90 (HSP90) is a highly conserved chaperone with an approximate molecular weight of 90-kDa. It plays a critical role in maintaining stability and homeostasis of oncoproteins, helping cancer cells living in the unsuitable
Externí odkaz:
https://doaj.org/article/51665c885b5c41e38d1562381c504eb4
Publikováno v:
International Journal of General Medicine. 15:6009-6019
Xu Liu,1,* Kelaier Yang,2,* Zhangfu Li,3 Jikui Liu1 1Department of Hepato-Pancreato-Biliary Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, Peopleâs Republic of China; 2Department of Endocrinology and Metabolism, Shenz