Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Zhangchun Guan"'
Autor:
Tian Lin, Dan Liu, Zhangchun Guan, Xuan Zhao, Sijin Li, Xu Wang, Rui Hou, Junnian Zheng, Jiang Cao, Ming Shi
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29382- (2024)
CRISPR-based screens have discovered novel functional genes involving in diverse tumor biology and elucidated the mechanisms of the cancer pathological states. Recently, with its randomness and unbiasedness, CRISPR screens have been used to discover
Externí odkaz:
https://doaj.org/article/1681110421ae473aa1a9da32d8de390d
Autor:
Yonggen Jia, Zhangchun Guan, Chenghua Liu, Minjun Huang, Jingjing Li, Jiannan Feng, Beifen Shen, Guang Yang
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Staphylococcus aureus is a common cause of inflammatory skin diseases, with one of its virulence factors, β-hemolysin (Hlb), known to promote skin colonization. However, its direct involvement in skin inflammation is unclear. In this study,
Externí odkaz:
https://doaj.org/article/08a641be4d214e26ae554bcbe9932490
Autor:
Fangjie Liu, Zhangchun Guan, Yu Liu, Jingjing Li, Chenghua Liu, Yaping Gao, Yuanfang Ma, Jiannan Feng, Beifen Shen, Guang Yang
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Staphylococcus aureus is a major pathogenic bacterium that causes a variety of clinical infections. The emergence of multi-drug resistant mechanisms requires novel strategies to mitigate S. aureus infection. Alpha-hemolysin (Hla) is a key virulence f
Externí odkaz:
https://doaj.org/article/2295fd9143bc426aa82515c421c8d4e7
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
IFN-γ is produced upon stimulation with S. aureus and may play a detrimental role during infection. However, whether hemolysins play a role in the mechanism of IFN-γ production has not been fully characterized. In this study, we demonstrated that H
Externí odkaz:
https://doaj.org/article/50c23cf5793544ba90dfb753537ba4b4
Autor:
Chendi Jing, Chenghua Liu, Yu Liu, Ruli Feng, Run Cao, Zhangchun Guan, Bo Xuan, Yaping Gao, Qi Wang, Nana Yang, Yuanfang Ma, Lefu Lan, Jiannan Feng, Beifen Shen, Hui Wang, Yanyan Yu, Guang Yang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Extracellular traps released by neutrophils (NETs) are essential for the clearance of Pseudomonas aeruginosa. Alkaline protease (AprA) secreted by P. aeruginosa negatively correlates with clinical improvement. Moreover, anti-AprA in patients with cys
Externí odkaz:
https://doaj.org/article/0f468465ab354d73b9f43d10a16cd170
Autor:
Chendi Jing, Chenghua Liu, Fangjie Liu, Yaping Gao, Yu Liu, Zhangchun Guan, Bo Xuan, Yanyan Yu, Guang Yang
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Staphylococcus aureus is a leading cause of Gram-positive bacterial infections worldwide; however, the treatment of S. aureus infection has become increasingly difficult due to the prevalence of methicillin-resistant S. aureus str
Externí odkaz:
https://doaj.org/article/504e659343814501aefdb26ad1b45576
Autor:
Xuan Zhao, Tong Ren, Sijin Li, Xu Wang, Rui Hou, Zhangchun Guan, Dan Liu, Junnian Zheng, Ming Shi
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 13, p5109-5126, 18p
Autor:
Chendi, Jing, Chenghua, Liu, Yu, Liu, Ruli, Feng, Run, Cao, Zhangchun, Guan, Bo, Xuan, Yaping, Gao, Qi, Wang, Nana, Yang, Yuanfang, Ma, Lefu, Lan, Jiannan, Feng, Beifen, Shen, Hui, Wang, Yanyan, Yu, Guang, Yang
Publikováno v:
Frontiers in Immunology
Extracellular traps released by neutrophils (NETs) are essential for the clearance of Pseudomonas aeruginosa. Alkaline protease (AprA) secreted by P. aeruginosa negatively correlates with clinical improvement. Moreover, anti-AprA in patients with cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9ef2e2ff55c0cf982f37471a5b1d0e0
https://pubmed.ncbi.nlm.nih.gov/33868297
https://pubmed.ncbi.nlm.nih.gov/33868297
Autor:
Chendi Jing, Chenghua Liu, Fangjie Liu, Yaping Gao, Liu, Yu, Zhangchun Guan, Xuan, Bo, Yanyan Yu, Yang, Guang
Figure S1. HlgABC, LukSF, and LukED proteins were expressed and analyzed by SDS-PAGE and Coomassie blue staining. (PDF 231 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6227dadfbf3358b6e4a111c55299c5a0
Autor:
Chendi Jing, Chenghua Liu, Fangjie Liu, Yaping Gao, Liu, Yu, Zhangchun Guan, Xuan, Bo, Yanyan Yu, Yang, Guang
Figure S4. Antibody affinity of YG8–1, YG8–2, and YG8–3 to HlgB (a), LukF (b), and LukD (c) determined with surface plasmon resonance (BIAcore). Anti-human IgG antibodies were immobilized on the carboxymethylated dextran surface of a CM5 chip,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a981b10afaa9b617e6526ecac6f756