Zobrazeno 1 - 10
of 419
pro vyhledávání: '"Zhang Yun-wu"'
Autor:
Xiang, Zheng-rui, Fan, Shi-rui, Ren, Juan, Ruan, Ting, Chen, Yuan, Zhang, Yun-wu, Wang, Yi-ting, Yu, Ze-zhou, Wang, Chao-fan, Sun, Xiao-long, Hao, Xiao-Jiang, Chen, Duo-Zhi
Publikováno v:
In European Journal of Medicinal Chemistry 5 December 2024 279
Autor:
Wang, Na, Cai, Lujian, Pei, Xinyu, Lin, Zhihao, Huang, Lihong, Liang, Chensi, Wei, Min, Shao, Lin, Guo, Tiantian, Huang, Fang, Luo, Hong, Zheng, Honghua, Chen, Xiao-fen, Leng, Lige, Zhang, Yun-wu, Wang, Xin, Zhang, Jie, Guo, Kai, Wang, Zhanxiang, Zhang, Hongsheng, Zhao, Yingjun, Xu, Huaxi
Publikováno v:
In iScience 21 June 2024 27(6)
Autor:
Zhang, Denghong, Zhang, Wei, Ming, Chen, Gao, Xuheng, Yuan, Huilong, Lin, Xiaojie, Mao, Xinru, Wang, Chunping, Guo, Xiaoyi, Du, Ying, Shao, Lin, Yang, Renzhi, Lin, Zhihao, Wu, Xilin, Huang, Timothy Y., Wang, Zhanxiang, Zhang, Yun-wu, Xu, Huaxi, Zhao, Yingjun
Publikováno v:
In Neuron 15 May 2024 112(10):1676-1693
Akademický článek
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Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 30 (2012)
Abstract Background β-site APP cleaving enzyme 1 (BACE1) cleaves β-amyloid precursor protein (APP) to initiate the production of β-amyloid (Aβ), the prime culprit in Alzheimer’s disease (AD). Dysregulation of the intracellular trafficking of BA
Externí odkaz:
https://doaj.org/article/8983d66c3671425aa20c8daed1404ee6
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 17 (2011)
Abstract Background It is well established that both cerebral hypoperfusion/stroke and type 2 diabetes are risk factors for Alzheimer's disease (AD). Recently, the molecular link between ischemia/hypoxia and amyloid precursor protein (APP) processing
Externí odkaz:
https://doaj.org/article/15a5eea6d8de496aa3d4f80181931acd
Publikováno v:
Molecular Brain, Vol 4, Iss 1, p 3 (2011)
Abstract An important pathological feature of Alzheimer's disease (AD) is the presence of extracellular senile plaques in the brain. Senile plaques are composed of aggregations of small peptides called β-amyloid (Aβ). Multiple lines of evidence dem
Externí odkaz:
https://doaj.org/article/17c94ae197f64016a50665055a8da5fc
Autor:
Zhang Xue, Zhang Yun-wu, Liu Shijie, Bulloj Ayelen, Tong Gary G, Zhang Zhuohua, Liao Francesca-Fang, Xu Huaxi
Publikováno v:
Molecular Neurodegeneration, Vol 1, Iss 1, p 7 (2006)
Abstract Background Aberrant hyperphosphorylation of tau protein has been implicated in a variety of neurodegenerative disorders. Although a number of protein kinases have been shown to phosphorylate tau in vitro and in vivo, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/0826380c87274291b9fdad317ce9cd40
Publikováno v:
Molecular Neurodegeneration, Vol 1, Iss 1, p 4 (2006)
Abstract Mutations in PSEN1 and PSEN2 genes account for the majority of cases of early-onset familial Alzheimer disease. Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both aca
Externí odkaz:
https://doaj.org/article/e630a7fdb5f34c85995aadff74e96e21
Autor:
Wang, Wanbing, Li, Yanzhong, Ma, Fangling, Sheng, Xuan, Chen, Kai, Zhuo, Rengong, Wang, Chen, Zheng, Honghua, Zhang, Yun-wu, Bu, Guojun, Chen, Xiao-Fen, Zhong, Li
Publikováno v:
In Brain Behavior and Immunity October 2023 113:275-288