Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zhanfang Kang"'
Publikováno v:
Innate Immunity, Vol 29 (2023)
Neutrophils constitute the first line of defense in human immunity and can be attracted to inflamed and infected sites by various chemokines. As essential players in immune processes, neutrophils theoretically play integral roles in the course of chr
Externí odkaz:
https://doaj.org/article/5ea30e45b147428b89a5ca416d85dcf4
Publikováno v:
Cardiovascular Therapeutics, Vol 2023 (2023)
The AMP-activated protein kinase (AMPK)/peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) pathway performs a crucial role in energy metabolism and mitochondrial network. Our previous study found that DT-010, a novel danshensu (D
Externí odkaz:
https://doaj.org/article/a8ce874d3d834cf3870761d780d19336
Autor:
Xiaojing Zhang, Baoyi Zhu, Peibin Lin, Xiaoping Liu, Jun Gao, Dazhong Yin, Jianwen Zeng, Baojian Liao, Zhanfang Kang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The widely used lipid-lowering drug niacin was reported to increase blood glucose in diabetes. How does niacin regulate β Cell function in diabetic patients remains unclear. This study aimed to investigate the effect of niacin on β cell lipotoxicit
Externí odkaz:
https://doaj.org/article/77d95210c71a4a85b9fdb9dfd5965aea
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The mitochondrial unfolded protein response (UPRmt) is a molecular mechanism that maintains mitochondrial proteostasis under stress and is closely related to various metabolic diseases, such as type 2 diabetes (T2D). Similarly, the unfolded protein r
Externí odkaz:
https://doaj.org/article/e6977cdfb9b94ee6b0f574c2d486e8e0
Autor:
Baoyi Zhu, Zhengfu Feng, Yan Guo, Tian Zhang, Ai Mai, Zhanfang Kang, Ting Weijen, Dai Wang, Dazhong Yin, Dongxing Zhu, Jun Gao
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Neutrophils form the first line of innate host defense against invading microorganisms. We previously showed that F0F1 ATP synthase (F-ATPase), which is widely known as mitochondrial respiratory chain complex V, is expressed in th
Externí odkaz:
https://doaj.org/article/f8c224414c3b46daa2e1d7b67deb6f8b
Autor:
Baoyi Zhu, Zhanfang Kang, Sihua Zhu, Yuying Zhang, Xiangmao Lai, Lilin Zhou, Hai Huang, Xiaofeng Gao, Chonghe Jiang, Jianwen Zeng
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Bladder outlet obstruction (BOO) is a common urologic disease associated with poorly understood molecular mechanisms. This study aimed to investigate the possible involvements of circRNAs (circular RNAs) and circRNA-encoded proteins in BOO developmen
Externí odkaz:
https://doaj.org/article/53383f48fc134e5c91ce710b5de8e7ab
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20443 (2011)
Type 2 diabetes is highly prevalent in the elderly population. Glucagon like Peptide-1 mimetic such as exendin-4 augments post-prandial insulin secretion. However, the potential influence of aging on the therapeutic effects of this peptide has not be
Externí odkaz:
https://doaj.org/article/0b35e33bc79348d0abdeac3ecf16f5d0
Publikováno v:
Natural Product Communications; Mar2024, Vol. 19 Issue 3, p1-16, 16p
Publikováno v:
Environmental Toxicology
Although enormous achievements have been made in targeted molecular therapies against hepatocellular carcinoma (HCC), the treatments can only prolong the life of patients with extrahepatic metastases. We evaluated thymoquinone (TQ), a compound from N
Publikováno v:
Frontiers in cell and developmental biology. 10
The mitochondrial unfolded protein response (UPR