Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Zhan-Hong Chen"'
Autor:
Ping Huang, Jia-huan Huang, Ya-bing Zheng, Wen-ming Cao, Xi-ying Shao, Jun-qing Chen, Yuan Huang, Guang-liang Li, K Sharma, Huan-huan Zhou, Xiao-jia Wang, Hong-chuan Jin, Zhan-hong Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Cardiotoxicity associated with the sequential use of anthracyclines followed by trastuzumab is common in adjuvant therapy of patients with HER2-positive early breast cancer (eBC). However, the cardiac safety of trastuzumab concurrent with
Externí odkaz:
https://doaj.org/article/b9ada211e4b54f6bacce908dbd891efc
Autor:
Zhao‐lei Zeng, Jia‐huan Lu, Yun Wang, Hui Sheng, Ying‐nan Wang, Zhan‐hong Chen, Qi‐nian Wu, Jia‐Bo Zheng, Yan‐xing Chen, Dong‐dong Yang, Kai Yu, Hai‐yu Mo, Jia‐jia Hu, Pei‐shan Hu, Ze‐xian Liu, Huai‐qiang Ju, Rui‐Hua Xu
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2423-2441 (2021)
Abstract Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorect
Externí odkaz:
https://doaj.org/article/39ec1ebf35c944a5aefe92e4611f5aa4
Autor:
Ting Li, Pei-Shan Hu, Zhixiang Zuo, Jin-Fei Lin, Xingyang Li, Qi-Nian Wu, Zhan-Hong Chen, Zhao-Lei Zeng, Feng Wang, Jian Zheng, Demeng Chen, Bo Li, Tie-Bang Kang, Dan Xie, Dongxin Lin, Huai-Qiang Ju, Rui-Hua Xu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract Background Colorectal carcinoma (CRC) is one of the most common malignant tumors, and its main cause of death is tumor metastasis. RNA N6-methyladenosine (m6A) is an emerging regulatory mechanism for gene expression and methyltransferase-lik
Externí odkaz:
https://doaj.org/article/76624111e6ca4679bf92d36b6906d172
Autor:
Zhan-Hong Chen, Jing-Jing Qi, Qi-Nian Wu, Jia-Huan Lu, Ze-Xian Liu, Yun Wang, Pei-Shan Hu, Ting Li, Jin-Fei Lin, Xiang-Yuan Wu, Lei Miao, Zhao-Lei Zeng, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu, Feng Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Abstract Background Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. However, little is kno
Externí odkaz:
https://doaj.org/article/4898116ca4344a52a40623baf9ce1d26
Autor:
Dong-Dong Yang, Zhan-Hong Chen, Kai Yu, Jia-Huan Lu, Qi-Nian Wu, Yun Wang, Huai-Qiang Ju, Rui-Hua Xu, Ze-Xian Liu, Zhao-Lei Zeng
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Methyltransferase-like 3 (METTL3), a major component of the N6-methyladenosine (m6A) methyltransferase complex, has been suggested to function as an oncogene in several cancers. However, its biological mechanism and the involved pathways in gastric c
Externí odkaz:
https://doaj.org/article/320f703d43ae4cefad4ebf15a5cd3738
Autor:
Tian-Tian Wang, Qing-Hua Cao, Ming-Yuan Chen, Qing Xia, Xin-Juan Fan, Xiao-Kun Ma, Qu Lin, Chang-Chang Jia, Min Dong, Dan-Yun Ruan, Ze-Xiao Lin, Jing-Yun Wen, Li Wei, Xing Li, Zhan-Hong Chen, Lei Wang, Xiang-Yuan Wu, Xiang-Bo Wan
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80317 (2013)
Autophagy can be tumor suppressive as well as promotive in regulation of tumorigenesis and disease progression. Accordingly, the prognostic significance of autophagy key regulator Beclin 1 was varied among different tumors. Here, we detected the clin
Externí odkaz:
https://doaj.org/article/adc78059c4f140c09588ea933c85aa77
Autor:
Qi Zhang, Dong-Hao Wu, Xiang-Yuan Wu, Ying-fen Hong, Hui-qiang Huang, Zhan-Hong Chen, Chang-Chang Jia, Tian-Tian Wang, Yang Li
Publikováno v:
Biochemical and Biophysical Research Communications. 558:14-21
Sorafenib remains the standard first-line treatment for advanced hepatocellular carcinoma (HCC), although other clinical trials are currently underway for treatments that show better curative effects. However, some patients are not sensitive to soraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06422124bd937a6545abfeaa0a42e81
https://doi.org/10.1016/j.bbrc.2021.04.047
https://doi.org/10.1016/j.bbrc.2021.04.047
Autor:
Jingjing Qi, Di Cui, Qi-Nian Wu, Qi Zhao, Zhan-Hong Chen, Lianjie Li, Walter Birchmeier, Yong Yu, Ran Tao
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3232
Metastasis is the main cause of death for patients suffering gastric cancer. Epithelial-mesenchymal transition (EMT) and cancer stem cells (CSC) are critical attributes of metastasis, both of which are regulated tightly by DNA methylation and Wnt/β-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822a0d9c20907214124781d823e71147
http://edoc.mdc-berlin.de/21780/1/21780oa.pdf
http://edoc.mdc-berlin.de/21780/1/21780oa.pdf
Autor:
Yan-Xing Chen, Huai-Qiang Ju, Zhan-Hong Chen, Jia-jia Hu, Rui-Hua Xu, Ying-Nan Wang, Jia-huan Lu, Hui Sheng, Yun Wang, Kai Yu, Pei-Shan Hu, Zexian Liu, Jia-Bo Zheng, Hai-Yu Mo, Qi-Nian Wu, Dong-dong Yang, Zhao-Lei Zeng
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2423-2441 (2021)
Cancer Medicine
Cancer Medicine
Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorectal cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6f10e4ef2f96f1beba2bbb34c0e055
https://doaj.org/article/39ec1ebf35c944a5aefe92e4611f5aa4
https://doaj.org/article/39ec1ebf35c944a5aefe92e4611f5aa4
Publikováno v:
FEBS Open Bio, Vol 10, Iss 4, Pp 525-534 (2020)
FEBS Open Bio
FEBS Open Bio
Prostate cancer (PCa) is the most prevalent cancer among men and the second leading cause of tumor‐associated deaths worldwide, with increasing incidence rates over the last 10 years. Recently, miR‐195 was reported to be hypermethylated at its pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b03c6dd8a569a37d467148d5b6217e
https://doaj.org/article/47d7b6ca8d31476a89f7b337f5bf61c4
https://doaj.org/article/47d7b6ca8d31476a89f7b337f5bf61c4