Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Zhan-Gong Zhao"'
Autor:
Robayet Chowdhury, Alexander T Taguchi, Laimonas Kelbauskas, Phillip Stafford, Chris Diehnelt, Zhan-Gong Zhao, Phillip C Williamson, Valerie Green, Neal W Woodbury
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1010773 (2023)
Past studies have shown that incubation of human serum samples on high density peptide arrays followed by measurement of total antibody bound to each peptide sequence allows detection and discrimination of humoral immune responses to a variety of inf
Externí odkaz:
https://doaj.org/article/8ae2241bc603481c92953c92f17717cd
Autor:
Robayet Chowdhury, Alexander T. Taguchi, Laimonas Kelbauskas, Philip Stafford, Chris Diehnelt, Zhan-Gong Zhao, Phillip C. Williamson, Valerie Green, Neal W. Woodbury
Past studies have shown that incubation of human serum samples on high density peptide arrays followed by measurement of total antibody bound to each peptide sequence allows detection and discrimination of humoral immune responses to a wide variety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fcc95542717399447ad1b8af2ba9132
https://doi.org/10.1101/2022.11.30.518471
https://doi.org/10.1101/2022.11.30.518471
Autor:
Zhan-Gong Zhao, Neal W. Woodbury, Chris W. Diehnelt, Joseph Barten Legutki, Boyd James G, Taguchi Alexander T
Publikováno v:
ACS Combinatorial Science. 22:500-508
In combinatorial chemical approaches, optimizing the composition and arrangement of building blocks toward a particular function has been done using a number of methods, including high throughput molecular screening, molecular evolution, and computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8f49c3212b31ca2e33eb4687b2ceb3
https://doi.org/10.1021/acscombsci.0c00003
https://doi.org/10.1021/acscombsci.0c00003
Autor:
Stephen Albert Johnston, John C. Lainson, Zhan Gong Zhao, Kathryn Sykes, Chris W. Diehnelt, Luhui Shen, Justin R. Brown
Publikováno v:
RSC Advances. 10:29675-29681
Parallel measurement of large numbers of antigen–antibody interactions are increasingly enabled by peptide microarray technologies. Our group has developed an in situ synthesized peptide microarray of >400 000 frameshift neoantigens using mask-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bf86667492fb4c241f7a488a8aa612
https://doi.org/10.1039/d0ra05267a
https://doi.org/10.1039/d0ra05267a
Autor:
Zhan-Gong Zhao, Stephen Albert Johnston, John C. Lainson, Nidhi Gupta, Valeriy Domenyuk, Chris W. Diehnelt
Publikováno v:
Bioconjugate Chemistry. 27:2505-2512
There is an ongoing need for affinity agents for emerging viruses and new strains of current human viruses. We therefore developed a robust and modular system for engineering high-affinity synbody ligands for the influenza A/Puerto Rico/8/1934 H1N1 v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d5de73c7e124fecab335f28ce6ba68
https://doi.org/10.1021/acs.bioconjchem.6b00447
https://doi.org/10.1021/acs.bioconjchem.6b00447
Autor:
Milene Tavares Batista, John C. Lainson, Valeriy Domenyuk, Andrey Loskutov, Chris W. Diehnelt, Nidhi Gupta, Joseph Barten Legutki, Stephen Albert Johnston, Zbigniew A. Cichacz, Joel F. Lusk, Phillip Stafford, Zhan-Gong Zhao
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Recent infectious outbreaks highlight the need for platform technologies that can be quickly deployed to develop therapeutics needed to contain the outbreak. We present a simple concept for rapid development of new antimicrobials. The goal was to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a55e28c0d8eea835fef61d46eb55ce5
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
There are an increasing variety of applications in which peptides are both synthesized and used attached to solid surfaces. This has created a need for high throughput sequence analysis directly on surfaces. However, common sequencing approaches that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28aab1c2d73ae6ec4082470cc42f37dc
http://europepmc.org/articles/PMC5736625
http://europepmc.org/articles/PMC5736625
Autor:
Matt Greving, Joseph Barten Legutki, Neal W. Woodbury, Phillip Stafford, Zhan-Gong Zhao, Stephen Albert Johnston
Publikováno v:
Nature communications. 5
There is an increasing awareness that health care must move from post-symptomatic treatment to presymptomatic intervention. An ideal system would allow regular inexpensive monitoring of health status using circulating antibodies to report on health f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb434991ff94af53033876f50ea17521
https://pubmed.ncbi.nlm.nih.gov/28079091
https://pubmed.ncbi.nlm.nih.gov/28079091
Application of 'one-bead one-compound' combinatorial library methods in signal transduction research
Publikováno v:
Life Sciences. 62:1577-1583
Using a “split-synthesis” solid phase synthetic approach, bead libraries can be generated such that each bead displays only one chemical entity. This “one-bead one-compound” combinatorial library can then be assayed for specific biological pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfae62c514e23aa49e0fd0457cb842b1
https://doi.org/10.1016/s0024-3205(98)00110-6
https://doi.org/10.1016/s0024-3205(98)00110-6
Autor:
Zhan-Gong Zhao, Kit S. Lam
Publikováno v:
Hematology/Oncology Clinics of North America. 11:1007-1019
Using the newly developed combinatorial peptide library methods, D-amino acid containing peptides that are specific against pan-B cell markers such as CD19, CD20, and CD22 can potentially be identified. These peptides can then be used as targeting ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c2ee491fd96917e3da335c065acea4
https://doi.org/10.1016/s0889-8588(05)70476-7
https://doi.org/10.1016/s0889-8588(05)70476-7