Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Zhan You Wang"'
Autor:
Yong-Gang Fan, Ri-Le Ge, Hang Ren, Rong-Jun Jia, Ting-Yao Wu, Xian-Fang Lei, Zheng Wu, Xiao-Bei Zhou, Zhan-You Wang
Publikováno v:
Pharmacological Research, Vol 209, Iss , Pp 107404- (2024)
Increased astrocytic lactoferrin (Lf) expression was observed in the brains of elderly individuals and Alzheimer's disease (AD) patients. Our previous study revealed that astrocytic Lf overexpression improved cognitive capacity by facilitating Lf sec
Externí odkaz:
https://doaj.org/article/cfa83bbb3a8a40c299a52a2cb2da56fd
Autor:
Yong-Gang Fan, Ting-Yao Wu, Ling-Xiao Zhao, Rong-Jun Jia, Hang Ren, Wen-Jia Hou, Zhan-You Wang
Publikováno v:
Pharmacological Research, Vol 199, Iss , Pp 107039- (2024)
Zinc is a crucial trace element in the human body, playing a role in various physiological processes such as oxidative stress, neurotransmission, protein synthesis, and DNA repair. The zinc transporters (ZnTs) family members are responsible for expor
Externí odkaz:
https://doaj.org/article/0edd1971273649bb8352175944f48a83
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The brain has long been considered an immune-privileged organ due to the presence of the blood-brain barrier (BBB). However, recent discoveries have revealed the underestimated role of T cells in the brain through the meningeal lymphatic system. Age
Externí odkaz:
https://doaj.org/article/98bb998c0e3b4ae5a4ce9523ec7532fe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neurodegenerative diseases (NDs) are chronic conditions that result in progressive damage to the nervous system, including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and Amyotrophic lateral sclerosis (ALS). A
Externí odkaz:
https://doaj.org/article/3c0e6bf52fac490597612af4d79e856d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/5ba3587e6bdb467e9f77f84234883def
Autor:
Qi Zhang, Zhen-Hua Wu, Shan-Shan Zhao, Jing Yang, Lei Chen, Xiao-Yu Wang, Zhan-You Wang, Hui-Xin Liu
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communicatio
Externí odkaz:
https://doaj.org/article/7889ba2b220f45f9897dd9de7f2668a2
Autor:
Ling-Xiao Zhao, Zhi-Qiang Gong, Qi Zhang, Da-Long He, Ri-Le Ge, Jin Meng, Hang Ren, Yong-Gang Fan, Zhan-You Wang
Publikováno v:
Journal of Controlled Release. 359:12-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e852bd9651060446a41737b588a0562d
https://doi.org/10.1016/j.jconrel.2023.05.035
https://doi.org/10.1016/j.jconrel.2023.05.035
Autor:
Yong-Gang Fan, Tian Guo, Xiao-Ran Han, Jun-Lin Liu, Yu-Ting Cai, Han Xue, Xue-Shi Huang, Yan-Chun Li, Zhan-You Wang, Chuang Guo
Publikováno v:
EBioMedicine, Vol 45, Iss , Pp 393-407 (2019)
Background: Recent studies have revealed that vitamin D deficiency may increase the risk of Alzheimer's disease, and vitamin D supplementation may be effective strategy to ameliorate the neurodegenerative process in Alzheimer's disease patients. Pari
Externí odkaz:
https://doaj.org/article/6b0b3eb1928d4e40ad3de769a632d818
Autor:
Jia-Zhen Wu, Mustafa Ardah, Caroline Haikal, Alexander Svanbergsson, Meike Diepenbroek, Nishant N. Vaikath, Wen Li, Zhan-You Wang, Tiago F. Outeiro, Omar M. El-Agnaf, Jia-Yi Li
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-15 (2019)
Abstract Background Progressive accumulation of α-synuclein is a key step in the pathological development of Parkinson’s disease. Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation in vitro and
Externí odkaz:
https://doaj.org/article/5804e97c94bb42328dfc122517329af0
Publikováno v:
Current Neuropharmacology. 21:67-86
Abstract: Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases worldwide. The occult nature of the onset and the uncertainty of the etiology largely impede the development of therapeutic strategies for AD. Previous studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f4710f738b43ca7cc35797c05dae8c
https://doi.org/10.2174/1570159x20666220817140737
https://doi.org/10.2174/1570159x20666220817140737