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Akademický článek

Single-cell RNA sequencing reveals epithelial cells driving brain metastasis in lung adenocarcinoma

Autor: Yonghui Wu, Fujun Yang, Shilan Luo, Xiang Li, Zhan Gu, Rui Fan, Yajuan Cao, Lixin Wang, Xiao Song

Publikováno v: iScience, Vol 27, Iss 3, Pp 109258- (2024)

Summary: Brain metastases (BM) of lung adenocarcinoma (LUAD) are the most common intracranial malignancy leading to death. However, the cellular origins and drivers of BM from LUAD have not been clarified. Cellular composition was characterized by si

Externí odkaz: https://doaj.org/article/22abb87588144ce9a361a92ea93ac97a

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Akademický článek

(−)-Guaiol inhibit epithelial-mesenchymal transition in lung cancer via suppressing M2 macrophages mediated STAT3 signaling pathway

Autor: Yajuan Cao, Yonghui Wu, Hongbin Tu, Zhan Gu, Fengzhi Yu, Weiling Huang, Liping Shen, Lixin Wang, Yan Li

Publikováno v: Heliyon, Vol 9, Iss 9, Pp e19817- (2023)

In the context of cancer expansion, epithelial-mesenchymal transition (EMT) plays an essential role in driving invasion and metastasis potential of cancer cells. Tumor-associated macrophages (TAMs)-derived factors involved in the initiation and progr

Externí odkaz: https://doaj.org/article/dabe528372634eaf87d37dc38d7629ee

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Akademický článek

Obesity and lipid-related parameters for predicting metabolic syndrome in Chinese elderly population

Autor: Zhan Gu, Ping Zhu, Qiao Wang, Huayu He, Jingjuan Xu, Li Zhang, Dong Li, Jianying Wang, Xiaojuan Hu, Guang Ji, Lei Zhang, Baocheng Liu

Publikováno v: Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)

Abstract Background The present study evaluated the predictive ability of five known “best” obesity and lipid-related parameters, including body mass index (BMI), waist-to-height ratio (WHtR), triglyceride-to-high-density-lipoprotein-cholesterol

Externí odkaz: https://doaj.org/article/4d596569f12c4eacb02e41301bb82fb8

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Akademický článek

Human microbiome brings new insights to traditional Chinese medicine

Autor: Rui-Rui Wang, PhD, Lei Zhang, MD, Jing-Juan Xu, PhD, Zhan Gu, PhD, Li Zhang, MS, Guang Ji, MD, Bao-Cheng Liu, PhD

Publikováno v: Journal of Bio-X Research, Vol 1, Iss 1, Pp 41-44 (2018)

Abstract. The human microbiome has become a new frontier of life sciences and plays a crucial role in determining individual and population health. Over thousands of years of medical practice, practitioners of traditional Chinese medicine (TCM) devel

Externí odkaz: https://doaj.org/article/6f8178fccfdd452085894e03aa7e7836

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