Identification of molecular genetic contributants to canine cutaneous mast cell tumour metastasis by global gene expression analysis

Autor: Tom Eve, Laura Blackwood, Debs Flack, Elena Fineberg, S. Murphy, Joyce Bass, Stuart Beaver, Mike Starkey, Trevor Whitbread, Kelly L. Bowlt Blacklock, Deborah Biasoli, Zeynap Birand, Jenny McKay, Stefano Di Palma, Richard Fox

Publikováno v: PLoS ONE
PLOS ONE
PLoS ONE, Vol 13, Iss 12, p e0208026 (2018)
Blacklock, K L B, Birand, Z, Biasoli, D, Fineberg, E, Murphy, S, Flack, D, Bass, J, Di Palma, S, Blackwood, L, McKay, J, Whitbread, T, Fox, R, Eve, T, Beaver, S & Starkey, M 2018, ' Identification of molecular genetic contributants to canine cutaneous mast cell tumour metastasis by global gene expression analysis ', PLoS ONE, vol. 13, no. 12, e0208026 . https://doi.org/10.1371/journal.pone.0208026

Cutaneous mast cell tumours are one of the most common canine cancers. Approximately 25% of the tumours metastasise. Activating c-kit mutations are present in about 20% of tumours, but metastases occur in the absence of mutations. Tumour metastasis i

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https://pubmed.ncbi.nlm.nih.gov/30566430