Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zeynab Fakhar"'
Autor:
Hamlet Khachatryan, Mher Matevosyan, Vardan Harutyunyan, Smbat Gevorgyan, Anastasiya Shavina, Irina Tirosyan, Yeva Gabrielyan, Marusya Ayvazyan, Marine Bozdaganyan, Zeynab Fakhar, Sajjad Gharaghani, Hovakim Zakaryan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The coronavirus disease 19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis with millions of confirmed cases and related deaths. The main protease (Mpro) of SARS-CoV-2 is cru
Externí odkaz:
https://doaj.org/article/55582fe9526c4ca39539949bbf3d1151
Autor:
Shakila Ghomashi, Reihane Ghomashi, Mohammad Sadegh Damavandi, Zeynab Fakhar, Seyedeh Yasaman Mousavi, Azhar Salari-Jazi, Sajjad Gharaghani, Ahmad Reza Massah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract In this study, eleven novel chromene sulfonamide hybrids were synthesized by a convenient method in accordance with green chemistry. At first, chromene derivatives (1–9a) were prepared through the multi-component reaction between aryl alde
Externí odkaz:
https://doaj.org/article/0fc154a6090641ae9827a20c7dd83307
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6ddb2454787f41be94d19c2dbee0242c
Publikováno v:
Medicine in Drug Discovery, Vol 21, Iss , Pp 100176- (2024)
Despite being the most widely prescribed and misused type of medication, opioids continue to function as robust pain relief agents; however, overdosing is a significant cause of fatalities among opioid users. The δ-opioid receptor (DOR) has immense
Externí odkaz:
https://doaj.org/article/d343eaea64cb4d81930ddeaa6fdd245a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract A new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide and become pandemic with thousands new deaths and infected cases globally. To address coronavirus disease (COVID-19), currently no effective dru
Externí odkaz:
https://doaj.org/article/56fdadd47ce44b4b95f39f40b4b20e7f
Autor:
Katyna J. Boussamba-Digombou, Maxleene Sandasi, Guy P. Kamatou, Sandy van Vuuren, Rafal Sawicki, Zeynab Fakhar, Alvaro M. Viljoen
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 948 (2022)
Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis which has become prevalent due to the emergence of resistant M. tuberculosis strains. The use of essential oils (EOs) as potential anti-infective agents to treat microbial infections
Externí odkaz:
https://doaj.org/article/936223e52c5b4fa98428b02979c3d966
Autor:
Mohamed F. Alajmi, Zeynab Fakhar, Imtaiyaz Hassan, Aijaz Ahmad, Deeba Shamim Jairajpuri, Shama Khan, Afzal Hussain
Publikováno v:
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
To address coronavirus disease (COVID-19), currently, no effective drug or vaccine is available. In this regard, molecular modeling approaches are highly useful to discover potential inhibitors of the main protease (Mpro) enzyme of SARS-CoV-2. Since,
Autor:
Leila Hejazi, Abraham Ebadi, Zeynab Fakhar, Maryam Nazari, Elham Rezaee, Sayyed Abbas Tabatabai
Publikováno v:
Chemistrybiodiversity. 19(11)
Soluble epoxide hydrolase enzyme (sEH) is one of the most promising and emerging targets to develop drugs for multiple disease indications, including hypertension, diabetes, stroke, dyslipidemia, pain, etc. Most inhibitor scaffolds have a urea or ami
Autor:
Zeynab Fakhar, Afzal Hussain, Preeti Gupta, Faizan Ahmad, Shama Khan, Md. Imtaiyaz Hassan, Asimul Islam, Md. Tabish Rehman, Mohamed F. Alajmi
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) is an upstream regulator of CaMKK-CaMKIV signaling cascade that activates various transcription factors, thereby regulating several cellular activities including, neuronal communication and immu
Publikováno v:
Journal of biomolecular structuredynamics. 40(15)
Inhibition of soluble epoxide hydrolase (sEH) is considered as an emerging druggable target to reduce blood pressure, improve insulin sensitivity, and decrease inflammation. Despite the availability of different classes of sEH small molecule inhibito