Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zeynab, Najafova"'
Autor:
Feda H Hamdan, Amro M Abdelrahman, Ana Patricia Kutschat, Xin Wang, Thomas L Ekstrom, Nidhi Jalan-Sakrikar, Catherine Wegner Wippel, Negar Taheri, Liezel Tamon, Waltraut Kopp, Joana Aggrey-Fynn, Aditya V Bhagwate, Roberto Alva-Ruiz, Isaac Lynch, Jennifer Yonkus, Robyn Laura Kosinsky, Jochen Gaedcke, Stephan A Hahn, Jens T Siveke, Rondell Graham, Zeynab Najafova, Elisabeth Hessmann, Mark J Truty, Steven A Johnsen
Publikováno v:
Gut. 72:1174-1185
ObjectivePancreatic ductal adenocarcinoma (PDAC) displays a remarkable propensity towards therapy resistance. However, molecular epigenetic and transcriptional mechanisms enabling this are poorly understood. In this study, we aimed to identify novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96374b93a79c5dd82550264fe249126b
https://doi.org/10.1136/gutjnl-2022-328154
https://doi.org/10.1136/gutjnl-2022-328154
Autor:
Vijayalakshmi Kari, Sanjay Kumar Raul, Jana Maria Henck, Julia Kitz, Frank Kramer, Robyn Laura Kosinsky, Nadine Übelmesser, Wael Yassin Mansour, Jessica Eggert, Melanie Spitzner, Zeynab Najafova, Holger Bastians, Marian Grade, Jochen Gaedcke, Florian Wegwitz, Steven A. Johnsen
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract Background Disruptor of telomeric silencing 1-like (DOT1L) is a non-SET domain containing methyltransferase known to catalyze mono-, di-, and tri-methylation of histone 3 on lysine 79 (H3K79me). DOT1L-mediated H3K79me has been implicated in
Externí odkaz:
https://doaj.org/article/201d59b1ad0f4a20bddf7cb919d29c35
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Pancreatic ductal adenocarcinoma (PDAC) displays a dismal prognosis due to late diagnosis and high chemoresistance incidence. For advanced disease stages or patients with comorbidities, treatment options are limited to gemcitabine alone or in combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::632db3edfad168c47f6f0b67c75237e8
https://doi.org/10.1158/0008-5472.c.6513556.v1
https://doi.org/10.1158/0008-5472.c.6513556.v1
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Tables S4 to S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23f15947587a1ecf902426e96af9667
https://doi.org/10.1158/0008-5472.22430146
https://doi.org/10.1158/0008-5472.22430146
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Figures S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6288dcab26989b52b9da6dbefd87adf9
https://doi.org/10.1158/0008-5472.22430152.v1
https://doi.org/10.1158/0008-5472.22430152.v1
Autor:
Steven A. Johnsen, Elisabeth Hessmann, Ivan Bogeski, Volker Ellenrieder, Philipp Ströbel, Jochen Gaedcke, Waltraut Kopp, Christine S. Gibhardt, Zeynab Najafova, Alexander Q. Wixom, Xin Wang, Feda H. Hamdan, Ana P. Kutschat
Supplementary Materials & Methods, Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0dcc1611a699d31c3a57d2704a986a
https://doi.org/10.1158/0008-5472.22430149.v1
https://doi.org/10.1158/0008-5472.22430149.v1
Autor:
Mark Wroblewski, Marina Scheller-Wendorff, Florian Udonta, Raimund Bauer, Jara Schlichting, Lin Zhao, Isabel Ben Batalla, Victoria Gensch, Sarina Päsler, Lei Wu, Marek Wanior, Hanna Taipaleenmäki, Simona Bolamperti, Zeynab Najafova, Klaus Pantel, Carsten Bokemeyer, Jun Qi, Eric Hesse, Stefan Knapp, Steven Johnsen, Sonja Loges
Publikováno v:
Haematologica, Vol 103, Iss 6 (2018)
Although inhibitors of bromodomain and extra terminal domain (BET) proteins show promising clinical activity in different hematologic malignancies, a systematic analysis of the consequences of pharmacological BET inhibition on healthy hematopoietic (
Externí odkaz:
https://doaj.org/article/118c713a5b524973a8616839fbd088f7
Autor:
Sankari Nagarajan, Tareq Hossan, Malik Alawi, Zeynab Najafova, Daniela Indenbirken, Upasana Bedi, Hanna Taipaleenmäki, Isabel Ben-Batalla, Marina Scheller, Sonja Loges, Stefan Knapp, Eric Hesse, Cheng-Ming Chiang, Adam Grundhoff, Steven A. Johnsen
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 460-469 (2014)
The estrogen receptor α (ERα) controls cell proliferation and tumorigenesis by recruiting various cofactors to estrogen response elements (EREs) to control gene transcription. A deeper understanding of these transcriptional mechanisms may uncover t
Externí odkaz:
https://doaj.org/article/b8a0bc339d144ab4ab88661385bcfe7e
Autor:
Steven A. Johnsen, Feda H. Hamdan, Elisabeth Hessmann, Christine S Gibhardt, Zeynab Najafova, Jochen Gaedcke, Philipp Ströbel, Ivan Bogeski, Volker Ellenrieder, Waltraut Kopp, Xin Wang, Ana P. Kutschat, Alexander Q. Wixom
Publikováno v:
Cancer Res
Pancreatic ductal adenocarcinoma (PDAC) displays a dismal prognosis due to late diagnosis and high chemoresistance incidence. For advanced disease stages or patients with comorbidities, treatment options are limited to gemcitabine alone or in combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4e97579d8b5e9744bc2d3a0e36615f
https://doi.org/10.1158/0008-5472.can-20-2874
https://doi.org/10.1158/0008-5472.can-20-2874
Autor:
Jan Tuckermann, Peng Liu, Florian Wegwitz, Zeynab Najafova, Liezel Tamon, Robyn Laura Kosinsky, Wanhua Xie, Mubashir Ahmad, Steven A. Johnsen
Publikováno v:
Cell Death Differ
The role of histone ubiquitination in directing cell lineage specification is only poorly understood. Our previous work indicated a role of the histone 2B ubiquitin ligase RNF40 in controlling osteoblast differentiation in vitro. Here, we demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69deae77458806294cf9302427eea8e6
https://pubmed.ncbi.nlm.nih.gov/32901120
https://pubmed.ncbi.nlm.nih.gov/32901120