Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zeying Fan"'
Autor:
Xiangyu Zhao, Ting Peng, Xunhong Cao, Yingping Hou, Ruifeng Li, Tingting Han, Zeying Fan, Ming Zhao, Yingjun Chang, Hebin Chen, Cheng Li, Xiaojun Huang
Publikováno v:
Cell Reports. 40:111342
Natural killer (NK) cells are lymphocytes that are involved in controlling tumors or microbial infections through the production of interferon gamma (IFN-γ). Granulocyte colony-stimulating factor (G-CSF) inhibits IFN-γ secretion by NK cells, but th
Publikováno v:
Cell Cycle. 15:1046-1059
Mesenchymal stem-like/claudin-low (MSL/CL) breast cancers are highly aggressive, express low cell-cell adhesion cluster containing claudins (CLDN3/CLDN4/CLDN7) with enrichment of epithelial-to-mesenchymal transition (EMT), immunomodulatory, and trans
Autor:
Susan Fosmire, Kathleen C. Torkko, Susan M. Edgerton, Hamid H. Gari, Rahul Ray, Christy M. Gearheart, Ann D. Thor, Zeying Fan, M. Scott Lucia, Gregory D. Degala, James R. Lambert, Christopher C. Porter
Publikováno v:
Oncotarget
// Hamid H. Gari 1 , Christy M. Gearheart 2 , Susan Fosmire 2 , Gregory D. DeGala 1 , Zeying Fan 1 , Kathleen C. Torkko 1 , Susan M. Edgerton 1 , M. Scott Lucia 1 , Rahul Ray 3 , Ann D. Thor 1 , Christopher C. Porter 2 and James R. Lambert 1 1 Depart
Autor:
Jennifer K. Richer, Ann D. Thor, Reema Wahdan-Alaswad, Steve M. Anderson, Susan M. Edgerton, Zeying Fan
Publikováno v:
Cancer Research. 75:P1-08
Background: Metabolic shifts in cancer and stem cells are well recognized (the so called Warburg Effect). Tumor cells frequently demonstrate alterations in lipid metabolism. The anti-diabetic drug metformin has been shown to have broad anti-cancer ac
Autor:
Xin-Sheng Deng, Jennifer K. Richer, Susan M. Edgerton, Zeying Fan, Sigrid Salling Arnadottir, Ann D. Thor, Reema Wahdan-Alaswad, Bolin Liu, Steven M. Anderson
Publikováno v:
Cell Cycle
Wahdan-Alaswad, R, Fan, Z, Edgerton, S M, Liu, B, Deng, X-S, Árnadóttir, S S, Richer, J K, Anderson, S M & Thor, A D 2013, ' Glucose promotes breast cancer aggression and reduces metformin efficacy ', Cell Cycle, vol. 12, no. 24 .
Wahdan-Alaswad, R, Fan, Z, Edgerton, S M, Liu, B, Deng, X-S, Árnadóttir, S S, Richer, J K, Anderson, S M & Thor, A D 2013, ' Glucose promotes breast cancer aggression and reduces metformin efficacy ', Cell Cycle, vol. 12, no. 24 .
Metformin treatment has been associated with a decrease in breast cancer risk and improved survival. Metformin induces complex cellular changes, resulting in decreased tumor cell proliferation, reduction of stem cells, and apoptosis. Using a carcinog
Autor:
RS Wahdan-Alsawad, Zeying Fan, Nicole S. Spoelstra, Susan M. Edgerton, Jennifer K. Richer, SS Arnadottir, Ann D. Thor
Publikováno v:
Cancer Research. 72:P5-10
BACKGROUND: We have previously shown that the anti-diabetic agent, metformin, inhibits cellular proliferation, colony formation and cell signaling, with an induction of S-phase arrest and apoptosis in triple negative (TN) breast cancer cell lines in
Autor:
Xiaoping Huang, Ann D. Thor, Susan M. Edgerton, Bolin Liu, Dalia Ordonez-Ercan, Zeying Fan, Xiaohe Yang
Publikováno v:
Molecular Cancer Research. 7:1882-1892
Increasing evidence suggests molecular interactions between erbB2 and other receptor tyrosine kinases, and estrogenic compounds and their cognate receptors. We have recently reported that downregulation of erbB3 abrogates erbB2-mediated tamoxifen res
Autor:
Irina Alimova, Bolin Liu, Thomas E. Dillon, Susan M. Edgerton, Ann D. Thor, Zeying Fan, Stuart E. Lind
Publikováno v:
Cell Cycle. 8:909-915
The anti-diabetic drug metformin reduces human cancer incidence and improves the survival of cancer patients, including those with breast cancer. We studied the activity of metformin against diverse molecular subtypes of breast cancer cell lines in v
Publikováno v:
International Journal of Cancer. 120:1874-1882
Receptor tyrosine kinase activity is essential for erbB2 (HER2/neu) promotion of breast carcinogenesis, metastasis and therapeutic resistance. erbB2 kinase can be activated by dimerization with another erbB receptor, most of which bind ligands. Of th
Publikováno v:
Cancer Research. 75:P3-04
Background: Co-morbidity of thyroid disease and breast cancer has been recognized for over a century. Up to two-thirds of women with breast cancer have clinical or occult thyroid disease, as compared to one fifth of unaffected females. Thyroid diseas