Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Zeyaul Islam"'
Autor:
Yasmin Abu Aqel, Aldana Alnesf, Idil I. Aigha, Zeyaul Islam, Prasanna R. Kolatkar, Adrian Teo, Essam M. Abdelalim
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-27 (2024)
Abstract Glucokinase (GCK), a key enzyme in glucose metabolism, plays a central role in glucose sensing and insulin secretion in pancreatic β-cells, as well as glycogen synthesis in the liver. Mutations in the GCK gene have been associated with vari
Externí odkaz:
https://doaj.org/article/94abed84c9244b8cb8991f8a4ba46a8d
Publikováno v:
ACS Omega, Vol 9, Iss 36, Pp 37650-37661 (2024)
Externí odkaz:
https://doaj.org/article/9ad18ed41c284532b5b83c94f40cdbbc
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The need for the early detection of emerging pathogenic viruses and their newer variants has driven the urgent demand for developing point-of-care diagnostic tools. Although nucleic acid-based methods such as reverse transcription-quantitative polyme
Externí odkaz:
https://doaj.org/article/d7f71b2cf6d14559adce15cf1f414d16
Autor:
Kripa S Keyan, Safa Salim, Swetha Gowda, Doua Abdelrahman, Syeda Sakina Amir, Zeyaul Islam, Claire Vargas, Maria Teresa Bengoechea-Alonso, Amira Alwa, Subrat Dahal, Prasanna R. Kolatkar, Sahar Da’as, Jerome Torrisani, Johan Ericsson, Farhan Mohammad, Omar M Khan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-17 (2023)
Abstract Transforming growth factor β (TGFβ) pathway is a master regulator of cell proliferation, differentiation, and death. Deregulation of TGFβ signalling is well established in several human diseases including autoimmune disorders and cancer.
Externí odkaz:
https://doaj.org/article/a71608c382a4486081a5585fd2c895d0
Autor:
Zeyaul Islam, Pankaj Kumar
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Multiple drug resistance is the main obstacle in the treatment of bacterial diseases. Resistance against antibiotics demands the exploration of new antimicrobial drug targets. A variety of in silico and genetic approaches show that the enzymes of the
Externí odkaz:
https://doaj.org/article/80165d08cc9d4d79a6fce36f317110fa
Autor:
Zeyaul Islam, Ameena Mohamed Ali, Adviti Naik, Mohamed Eldaw, Julie Decock, Prasanna R. Kolatkar
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Higher eukaryotic development is a complex and tightly regulated process, whereby transcription factors (TFs) play a key role in controlling the gene regulatory networks. Dysregulation of these regulatory networks has also been associated with carcin
Externí odkaz:
https://doaj.org/article/25f7b5fc82a4447a8f96304fef6cb550
Autor:
Hyung-Goo Kim, Jill A. Rosenfeld, Daryl A. Scott, Gerard Bénédicte, Jonathan D. Labonne, Jason Brown, Marianne McGuire, Sonal Mahida, Sakkubai Naidu, Jacqueline Gutierrez, Gaetan Lesca, Vincent des Portes, Ange-Line Bruel, Arthur Sorlin, Fan Xia, Yline Capri, Eric Muller, Dianalee McKnight, Erin Torti, Franz Rüschendorf, Oliver Hummel, Zeyaul Islam, Prasanna R. Kolatkar, Lawrence C. Layman, Duchwan Ryu, Il-Keun Kong, Suneeta Madan-Khetarpal, Cheol-Hee Kim
Publikováno v:
Molecular Autism, Vol 10, Iss 1, Pp 1-15 (2019)
Abstract Background PHF21A has been associated with intellectual disability and craniofacial anomalies based on its deletion in the Potocki-Shaffer syndrome region at 11p11.2 and its disruption in three patients with balanced translocations. In addit
Externí odkaz:
https://doaj.org/article/f02d9289960547e38357f179ca8011af
Publikováno v:
Molecules, Vol 27, Iss 13, p 4037 (2022)
Obesity is a chronic disease with increasing cases among children and adolescents. Melanocortin 4 receptor (MC4R) is a G protein-coupled transporter involved in solute transport, enabling it to maintain cellular homeostasis. MC4R mutations are associ
Externí odkaz:
https://doaj.org/article/35ea093e29f64f049e9e1bc814a8a59d
Autor:
Vijay Gupta, Indulekha P Sudhakaran, Zeyaul Islam, Nishant N Vaikath, Issam Hmila, Tamas Lukacsovich, Prasanna R Kolatkar, Omar M A El-Agnaf
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241773 (2020)
Aggregation of α-synuclein (α-syn) has been implicated in multiple neurodegenerative disorders including Parkinson's disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), collectively grouped as synucleinopathies. Recentl
Externí odkaz:
https://doaj.org/article/e6b990990aae455eb1b643413ba84c07
Publikováno v:
Molecules, Vol 27, Iss 3, p 1105 (2022)
Fibrin-based systems offer promises in drug and gene delivery as well as tissue engineering. We established earlier a fibrin-based plasma beads (PB) system as an efficient carrier of drugs and antigens. In the present work, attempts were made to furt
Externí odkaz:
https://doaj.org/article/62812402715a4d06aabd71ff7bd48c1f