Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zexu, Fang"'
Publikováno v:
Chinese Chemical Letters. 34:107295
Publikováno v:
Chinese Chemical Letters. :108128
Autor:
Alykhan Motani, Juan C. Jaen, Helen Fuentes, Nigel Walker, Zhulun Wang, Lawrence R. McGee, Zexu Fang, Jocelyn Staunton, Jennifer Weiszmann, Qingxiang Liu, Jinsong Liu, Yang Li, Gary Lee, Jin-Long Chen, R. Marc Learned, Michelle Lindstrom, Donna H.T. Biermann
Publikováno v:
Journal of Molecular Biology. 386:1301-1311
The nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPAR gamma; NR1C3) plays a central role in adipogenesis and is the molecular target of the thiazolidinedione class of antidiabetic drugs. To overcome the well-known shortc
Publikováno v:
Anesthesia & Analgesia. 87:963-966
We assessed the effect of rat strain on susceptibility to anesthesia and convulsions produced by inhaled compounds. We determined the minimum alveolar anesthetic concentration (MAC) of desflurane and nitrous oxide, and the convulsive 50% effective do
Autor:
Edmond I. Eger, Donald D. Koblin, Diane Gong, Zexu Fang, James R. Trudell, Pompiliu Ionescu, Michael J. Halsey, Michael J. Laster
Publikováno v:
Anesthesia & Analgesia. 87:419-424
We assessed the anesthetic properties of helium and neon at hyperbaric pressures by testing their capacity to decrease anesthetic requirement for desflurane using electrical stimulation of the tail as the anesthetic endpoint (i.e., the minimum alveol
Autor:
Zexu Fang, Michael J. Laster, Donald D. Koblin, Michael J. Halsey, Edmond I. Eger, Pompiliu Ionescu, James M. Sonner
Publikováno v:
Anesthesia & Analgesia. 85:1149-1153
Anesthetics depress the central nervous system, whereas nonimmobilizers (previously called nonanesthetics) and transitional compounds having the same physical properties (e.g., solubility in lipid) do not produce anesthesia (nonimmobilizers) or are l
Autor:
Michael J. Laster, Zexu Fang, James M. Sonner, L. Kandel, Ben S. Chortkoff, Edmond I. Eger, Pompiliu Ionescu
Publikováno v:
Anesthesia & Analgesia. 84:1042-1048
The mechanism by which n-alkanols produce anesthesia and the characteristics relevant to those mechanisms (e.g., lipid solubilities versus potencies) remain unknown. Accordingly, we determined potencies (minimum alveolar anesthetic concentration [MAC
Publikováno v:
Anesthesia & Analgesia. 84:852-858
The potency of conventional inhaled anesthetics increases with increasing age: the 50% effective dose (minimum alveolar anesthetic concentration [MAC]) for anesthesia in the neonatal animal or human exceeds MAC in the young adult by approximately 30%
Autor:
Richard B. Weiskopf, Michael J. Laster, Edmond I. Eger, James M. Sonner, Terri Bowland, Pompiliu Ionescu, Diane Gong, Zexu Fang, Donald D. Koblin
Publikováno v:
Anesthesia & Analgesia. 84:160-168
Present package labeling for sevoflurane recommends the use of fresh gas flow rates of 2 L/min or more when delivering anesthesia with sevoflurane. This recommendation resulted from a concern about the potential nephrotoxicity of a degradation produc
Publikováno v:
Anesthesia & Analgesia. 82:775-781
Various alkali (e.g., soda lime) convert sevoflurane to CF2=C(CF3)OCH2F, a vinyl ether called "Compound A, " whose toxicity raises concerns regarding the safe administration of sevoflurane via rebreathing circuits. In the present investigation, we me