Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Zev J Gartner"'
Autor:
Kimberly M Sogi, Zev J Gartner, Mark A Breidenbach, Mason J Appel, Michael W Schelle, Carolyn R Bertozzi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65080 (2013)
The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate-dep
Externí odkaz:
https://doaj.org/article/b9b0a37a4d504cb69bdfc8b21cf1c5b6
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Sample multiplexing enables pooled analysis during single-cell RNA sequencing workflows, thereby increasing throughput and reducing batch effects. A challenge for all multiplexing techniques is to link sample-specific barcodes with cell-spec
Externí odkaz:
https://doaj.org/article/773b85be36454f5db3c7796fdaa0bd4a
Autor:
Efren A. Reyes, David Castillo-Azofeifa, Jérémie Rispal, Tomas Wald, Rachel K. Zwick, Brisa Palikuqi, Angela Mujukian, Shervin Rabizadeh, Alexander R. Gupta, James M. Gardner, Dario Boffelli, Zev J. Gartner, Ophir D. Klein
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
The gastrointestinal tract relies on the production, maturation, and transit of mucin to protect against pathogens and to lubricate the epithelial lining. Although the molecular and cellular mechanisms that regulate mucin production and movement are
Externí odkaz:
https://doaj.org/article/6e8bbf33ec144be58c7912b2853fe1d7
Autor:
Asa Thibodeau, Alper Eroglu, Christopher S. McGinnis, Nathan Lawlor, Djamel Nehar-Belaid, Romy Kursawe, Radu Marches, Daniel N. Conrad, George A. Kuchel, Zev J. Gartner, Jacques Banchereau, Michael L. Stitzel, A. Ercument Cicek, Duygu Ucar
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Detecting multiplets in single nucleus (sn)ATAC-seq data is challenging due to data sparsity and limited dynamic range. AMULET (ATAC-seq MULtiplet Estimation Tool) enumerates regions with greater than two uniquely aligned reads across the ge
Externí odkaz:
https://doaj.org/article/16ab6a3786b04036bf43b168af964002
Autor:
Jesse Q. Zhang, Christian A. Siltanen, Ata Dolatmoradi, Chen Sun, Kai-Chun Chang, Russell H. Cole, Zev J. Gartner, Adam R. Abate
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Droplet libraries consisting of many reagents encapsulated in separate droplets are necessary for applications of microfluidics, including combinatorial chemical synthesis, DNA-encoded libraries, and massively multiplexed PCR. However, exist
Externí odkaz:
https://doaj.org/article/f3cff36afa924cc0a4bb916acd1bb7cd
Autor:
Christopher S. McGinnis, David A. Siegel, Guorui Xie, George Hartoularos, Mars Stone, Chun J. Ye, Zev J. Gartner, Nadia R. Roan, Sulggi A. Lee
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background Single-cell RNA sequencing (scRNA-seq) provides high-dimensional measurements of transcript counts in individual cells. However, high assay costs and artifacts associated with analyzing samples across multiple sequencing runs limi
Externí odkaz:
https://doaj.org/article/bea83cbdb3b44163b4655e3d340c2253
Autor:
Jesse Q. Zhang, Christian A. Siltanen, Leqian Liu, Kai-Chun Chang, Zev J. Gartner, Adam R. Abate
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phenotypes of interest can be observed through changes in gene expression. Linking sequencing with optical analysis has provided insight into the
Externí odkaz:
https://doaj.org/article/69a95d5fde8a49fdb857cf024e843d5c
Autor:
Katelyn A. Cabral, Vasudha Srivastava, Austin J. Graham, Maxwell C. Coyle, Connor Stashko, Valerie Weaver, Zev J. Gartner
Publikováno v:
Tissue Engineering Part A. 29:80-92
The construction of three-dimensional (3D) microvascular networks with defined structures remains challenging. Emerging bioprinting strategies provide a means of patterning endothelial cells (ECs) into the geometry of 3D microvascular networks, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e358f665a84168332478c030ffbe8d5
https://doi.org/10.1089/ten.tea.2022.0072
https://doi.org/10.1089/ten.tea.2022.0072
Single-cell sample multiplexing technologies function by associating sample-specific barcode tags with cell-specific barcode tags, thereby increasing sample throughput, reducing batch effects, and decreasing reagent costs. Computational methods must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::174ab9d1e6c6e3546992d9de7a5ff3e2
https://doi.org/10.1101/2023.04.11.536275
https://doi.org/10.1101/2023.04.11.536275
Autor:
Sisi Chen, Andrew W. Bremer, Olivia J. Scheideler, Yun Suk Na, Michael E. Todhunter, Sonny Hsiao, Prithvi R. Bomdica, Michel M. Maharbiz, Zev J. Gartner, David V. Schaffer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
In vitroassays involving multiple cell types cannot control the stoichiometry or contact times of cell-cell interactions. Here, the authors present a patterned co-culture platform based on printed oligonucleotides capable of controlling cell-cell int
Externí odkaz:
https://doaj.org/article/55b29f78522547ffa0cce3eafe375b99