Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zertashia Akram"'
Autor:
Zertashia Akram, Ishrat Mahjabeen, Faiza Irshad, Malik Waqar Ahmed, Sadaf Rehman, Muhammad Rizwan, Amna Shafqat, Aniqa Kiran, Asma Saeed
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Abnormal uterine bleeding (AUB) is irregular menstrual bleeding which has great impact on female health and life style. Various genetic factors are involved in etiology and pathology of AUB. Present study was designed to explore t
Externí odkaz:
https://doaj.org/article/6c50869c098c45e5ad66bba95b5f62b3
Autor:
Maria Fazal Ul Haq, Muhammad Zahid Hussain, Ishrat Mahjabeen, Zertashia Akram, Nadia Saeed, Rabia Shafique, Sumaira Fida Abbasi, Mahmood Akhtar Kayani
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281840 (2023)
Mitochondrial sirtuins have diverse role specifically in aging, metabolism and cancer. In cancer, these sirtuins play dichotomous role as tumor suppressor and promoter. Previous studies have reported the involvement of sirtuins in different cancers.
Externí odkaz:
https://doaj.org/article/f7715f90ba4544d582abef039b320b06
Autor:
Zertashia Akram, Ishrat Mahjabeen, Muhammad Umair, Muhammad Fahim, Mahmood Akhter Kayani, Lulu Fatima, Malik Waqar Ahmad, Sarwat Jahan, Tayyaba Afsar, Ali Almajwal, Nawaf W Alruwaili, Iftikhar Ali Khawar, Suhail Razak
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273211 (2022)
Arsenic exposure alters redox balance, induces DNA damage, and deregulates many genes. OGG1 gene involved in base repair mechanism, for excision of 8-oxoguanine (8-oxoG) from DNA formed as a result of accumulation of ROS in cell. HPRT gene encode tra
Externí odkaz:
https://doaj.org/article/7b578379051345f0be489b7c52494355
Publikováno v:
Toxicology and Industrial Health. 36:161-169
Increasing anthropogenic activities related to industrialization and exposure to different toxicants increases the health hazards of industrial workers. Arsenic (As) exposure induces DNA damage and generates reactive oxygen species, which may result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8672eb2d451625466cb0d0713fceb6f4
https://doi.org/10.1177/0748233720918680
https://doi.org/10.1177/0748233720918680
Autor:
Faisal Rahman, Muhammad Zahid Hussain, Bushra Arif, Asad U. Khan, Ishrat Mahjabeen, Zertashia Akram, Malik Waqar Ahmed, Mahmood Akhtar Kayani, Saqiba Ahmad
Publikováno v:
Environmental Science and Pollution Research. 27:11425-11437
Ubiquitin-proteasome system (UPS) gene, PSMD1, is an important gene for neutralization of damaged and misfolded protein(s). The current study was designed to study the genetic and expression variations of PSMD1 gene as a consequence of arsenic exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a1b858ee338e6b860180cdd618f9d6
https://doi.org/10.1007/s11356-019-07422-x
https://doi.org/10.1007/s11356-019-07422-x
Autor:
Shahzad Yousaf, Asad U. Khan, Iram Nadeem, Zertashia Akram, Bilquis Begum, Mahmood Akhtar Kayani, Ishrat Mahjabeen
Publikováno v:
Cancer Genetics. 237:39-50
This study was designed to check correlation of mRNA and protein expression of BER pathway genes(XRCC1, OGG1) and a proliferation marker (Ki-67) in 100 gastric tissue samples and controls (adjacent uninvolved area). The expression was estimated using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f2c1ea4a8e529c3abe0027230361d8
https://doi.org/10.1016/j.cancergen.2019.06.002
https://doi.org/10.1016/j.cancergen.2019.06.002
Autor:
Malik Waqar Ahmed, Mahmood Akhtar Kayani, Zertashia Akram, Asad U. Khan, Saima Ameen, Ishrat Mahjabeen, Anum Zehra Naqvi
Publikováno v:
Bioscience Reports
The present study was designed to determine the association between the genetic polymorphisms/expression variations of RB1 and CCND1 genes and brain tumor risk. For this purpose, 250 blood samples of brain tumor patients along with 250 controls (coho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3e4555f7ea9c02b83223b83e265e39
https://doi.org/10.1042/bsr20190629
https://doi.org/10.1042/bsr20190629
Publikováno v:
Journal of Histotechnology. 41:149-159
Arsenic-contaminated drinking water and its association to different diseases has been considered a severe problem worldwide. The goal of the present study was to evaluate the histopathological cha...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6101267ad352317b6a0469dbf801fbea
https://doi.org/10.1080/01478885.2018.1484330
https://doi.org/10.1080/01478885.2018.1484330
Autor:
Hizbullah Wazir, Sarwat Jahan, Malik Waqar Ahmad, Sadaf Riaz, Mahmood Akhtar Kayani, Zertashia Akram, Muhammad Abaid Ullah, Ishrat Mahjabeen
Publikováno v:
Archives of environmentaloccupational health. 74(4)
Oxidative stress and DNA damage are considered as possible mechanisms involved in lead toxicity. To test this hypothesis, DNA damage and expression variations of aminolevulinic acid dehydratase (ALAD), superoxide dismutase 2 (SOD2), and 8-oxoguanine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828b6da66bac959d74fa2094c6f2d343
https://pubmed.ncbi.nlm.nih.gov/29336731
https://pubmed.ncbi.nlm.nih.gov/29336731
Autor:
Maryam Raza, Mahmood Akhtar Kayani, Waqar Ahmad Malik, Zertashia Akram, Muhammad Faisal Fahim, Asad U. Khan, Ayesha Khan, Ishrat Mahjabeen
Publikováno v:
Environmental science and pollution research international. 25(33)
Occupational exposure accounts for a contact between workers and different toxicants. Present study was designed to measure the arsenic-induced DNA fragmentation and oxidative stress in exposed workers. Blood, hair, and nail samples were collected fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a7312c664f83f398170104aa22efa6
https://pubmed.ncbi.nlm.nih.gov/30259327
https://pubmed.ncbi.nlm.nih.gov/30259327