Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats.

Autor: Grigorova YN; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Juhasz O; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Long JM; Laboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Zernetkina VI; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Hall ML; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Wei W; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Morrell CH; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Petrashevskaya N; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Morrow A; Laboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, NIH, Baltimore, MD 21224, USA., LaNasa KH; Laboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Bagrov AY; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Rapp PR; Laboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Fedorova OV; Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD 21224, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 20; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 20.

Synthesis of an Endogenous Steroidal Na Pump Inhibitor Marinobufagenin, Implicated in Human Cardiovascular Diseases, Is Initiated by CYP27A1 via Bile Acid Pathway.

Autor: Fedorova OV; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD. fedorovo@mail.nih.gov BagrovA@mail.nih.gov., Zernetkina VI; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Shilova VY; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Grigorova YN; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Juhasz O; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Wei W; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Marshall CA; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Lakatta EG; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD., Bagrov AY; From the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD. fedorovo@mail.nih.gov BagrovA@mail.nih.gov.

Publikováno v: Circulation. Cardiovascular genetics [Circ Cardiovasc Genet] 2015 Oct; Vol. 8 (5), pp. 736-45. Date of Electronic Publication: 2015 Sep 15.