Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Zequn Yin"'
Autor:
Ke Gong, Chao Xue, Zian Feng, Ruru Pan, Mengyao Wang, Shasha Chen, Yuanli Chen, Yudong Guan, Lingyun Dai, Shuang Zhang, Liwei Jiang, Ling Li, Bei Wang, Zequn Yin, Likun Ma, Yasuko Iwakiri, Junming Tang, Chenzhong Liao, Houzao Chen, Yajun Duan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Glucagon-like peptide 1 (GLP1), which is mainly processed and cleaved from proglucagon in enteroendocrine cells (EECs) of the intestinal tract, acts on the GLP1 receptor in pancreatic cells to stimulate insulin secretion and to inhibit gluca
Externí odkaz:
https://doaj.org/article/1d9a0f1f82234740abfd2dd4050318bc
Autor:
Chao Xue, Peng Zeng, Ke Gong, Qian Li, Zian Feng, Mengyao Wang, Shasha Chen, Yanfang Yang, Jiaqi Li, Shuang Zhang, Zequn Yin, Yingquan Liang, Tengteng Yan, Miao Yu, Ke Feng, Dan Zhao, Xiaoxiao Yang, Xia Zhang, Likun Ma, Yasuko Iwakiri, Liang Chen, Xiaoqiang Tang, Yuanli Chen, Houzao Chen, Yajun Duan
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114691- (2024)
Summary: The strategy of lowering cholesterol levels by promoting cholesterol excretion is still lacking, and few molecular targets act on multiple cholesterol metabolic processes. In this study, we find that Nogo-B deficiency/inhibition simultaneous
Externí odkaz:
https://doaj.org/article/55bf1da42cdf44debe25ff75e80976f0
Autor:
Xianshe Meng, Shihong Zheng, Zequn Yin, Xuerui Wang, Daigang Yang, Tingfeng Zou, Huaxin Li, Yuanli Chen, Chenzhong Liao, Zhouling Xie, Xiaodong Fan, Jihong Han, Yajun Duan, Xiaoxiao Yang
Publikováno v:
Food Science and Human Wellness, Vol 13, Iss 1, Pp 211-224 (2024)
Psoriasis is a chronic autoimmune disease featured by patches on the skin. It is caused by malfunction of immune cells and keratinocytes with inflammation as one of its key features. Apigenin (API) is a natural flavonoid with anti-inflammatory and im
Externí odkaz:
https://doaj.org/article/6988ac0544fe4466a96a186760f1e7ce
Autor:
Ke Gong, Chao Xue, Zian Feng, Ruru Pan, Mengyao Wang, Shasha Chen, Yuanli Chen, Yudong Guan, Lingyun Dai, Shuang Zhang, Liwei Jiang, Ling Li, Bei Wang, Zequn Yin, Likun Ma, Yasuko Iwakiri, Junming Tang, Chenzhong Liao, Houzao Chen, Yajun Duan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/827f1dba35394e18b0bf96bda4c4ab86
Autor:
Yanfang Yang, Ke Feng, Liying Yuan, Yuxin Liu, Mengying Zhang, Kaimin Guo, Zequn Yin, Wenjia Wang, Shuiping Zhou, He Sun, Kaijing Yan, Xijun Yan, Xuerui Wang, Yajun Duan, Yunhui Hu, Jihong Han
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1036-1052 (2023)
Heart failure is the leading cause of death worldwide. Compound Danshen Dripping Pill (CDDP) or CDDP combined with simvastatin has been widely used to treat patients with myocardial infarction and other cardiovascular diseases in China. However, the
Externí odkaz:
https://doaj.org/article/4e8625d8828146368c7a3292cab2b030
Autor:
Xuerui Wang, Zequn Yin, Xianshe Meng, Daigang Yang, Huawen Meng, Chenzhong Liao, Lingling Wei, Yuanli Chen, Xiaoxiao Yang, Jihong Han, Yajun Duan, Shuang Zhang
Publikováno v:
Journal of Functional Foods, Vol 92, Iss , Pp 105060- (2022)
Parkinson's disease (PD) is the most common neurodegenerative disease. Daidzein (DAI) is one of the most commonly ingested phytoestrogens with anti-oxidant properties. However, the effects of DAI on oxidative stress in PD has not been reported. In th
Externí odkaz:
https://doaj.org/article/d9274367c3884fd68bbc87fbfc516f21
Autor:
Mengyao Wang, Feng Zhang, Jie Zhou, Ke Gong, Shasha Chen, Xinran Zhu, Mengxue Zhang, Yajun Duan, Chenzhong Liao, Jihong Han, Zequn Yin
Publikováno v:
Nutrients, Vol 15, Iss 9, p 2157 (2023)
Licorice is a traditional and versatile herbal medicine and food. Glabridin (Gla) is a kind of isoflavone extracted from the licorice root, which has anti-obesity, anti-atherosclerotic, and antioxidative effects. Alcoholic liver disease (ALD) is a wi
Externí odkaz:
https://doaj.org/article/1bf644bc6b0a40feb9132c1121fb34d3
Autor:
Dandan Wang, Zequn Yin, Lan Han, Mengxue Zhang, Huaxin Li, Xiaoxiao Yang, Yuanli Chen, Shuang Zhang, Jihong Han, Yajun Duan
Publikováno v:
Journal of Functional Foods, Vol 88, Iss , Pp 104901- (2022)
It has been reported that ascorbic acid inhibits non-alcoholic fatty liver disease partially by activating fatty acid β-oxidation. However, little is known about the mechanism of ascorbic acid-mediated lipid synthesis. Western blot, qRT-PCR and immu
Externí odkaz:
https://doaj.org/article/cd3be17dbab74b0dbb9d9423caa63438
Autor:
Xuerui Wang, Zequn Yin, Peichang Cao, Shihong Zheng, Yuanli Chen, Maoyun Yu, Chenzhong Liao, Zhongyuan Zhang, Yajun Duan, Jihong Han, Shuang Zhang, Xiaoxiao Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 110964- (2021)
Alzheimer’s disease (AD) is the most common neurodegenerative disease in aging population. Neuroinflammation, hyperphosphorylated Tau (p-Tau) and the imbalance between production and clearance of β-amyloid peptide (Aβ) are the major causes for AD
Externí odkaz:
https://doaj.org/article/383de31991ec4d31bc03d6ab1932105d
Autor:
Zequn Yin, Xuerui Wang, Shihong Zheng, Peichang Cao, Yuanli Chen, Maoyun Yu, Chenzhong Liao, Zhongyuan Zhang, Jihong Han, Yajun Duan, Xiaoxiao Yang, Shuang Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. It may be caused by oxidative stress, inflammation, and cerebrovascular dysfunctions in the brain. LongShengZhi Capsule (LSZ), a traditional Chinese medicine, has been app
Externí odkaz:
https://doaj.org/article/e93e451278e64541baca78edb9a16ab9