Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Zeping xie"'
Publikováno v:
iRADIOLOGY, Vol 1, Iss 4, Pp 320-339 (2023)
Abstract Pyrophosphate (PPi) anions are crucial in numerous biological and ecological processes involved in energy conversion, enzymatic reactions, and metabolic regulation along with adenosine. They are also significant biological markers for variou
Externí odkaz:
https://doaj.org/article/b5c5e28e191a47a4b63f0303bd2cc1c4
Autor:
Ting Zeng, Junjie Li, Lingpeng Xie, Zhaoyang Dong, Qing Chen, Sha Huang, Shuwen Xie, Yuqi Lai, Jun Li, Weixin Yan, YuHua Wang, Zeping Xie, Changlei Hu, Jiayi Zhang, Shanshan Kuang, Yuhong Song, Lei Gao, Zhiping Lv
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Neuronal iron overload contributes to synaptic damage and neuropsychiatric disorders. However, the molecular mechanisms underlying iron deposition in depression remain largely unexplored. Our study aims to investigate how nuclear factor-eryt
Externí odkaz:
https://doaj.org/article/d69f373ffa33451189ff96b802a5612a
Autor:
Zhi Li, Lijuan Kou, Xinzhen Fu, Zeping Xie, Maolei Xu, Lin Guo, Tiantian Lin, Shizhou Gong, Shumin Zhang, Ming Liu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1514-1526 (2022)
A series of novel dual A2A/A2B AR antagonists based on the triazole-pyrimidine-methylbenzonitrile core were designed and synthesised. The A2A AR antagonist cAMP functional assay results were encouraging for most target compounds containing quinoline
Externí odkaz:
https://doaj.org/article/dae3bf8349fc4ffbbbb6c97e675391dc
Autor:
Sixia Yang, Zeping xie, Tingting Pei, Yi zeng, Qiaowu Xiong, Hui Wei, Yong Wang, Weidong Cheng
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-18 (2022)
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disease. Ferroptosis plays a critical role in neurodegenerative diseases. Nuclear factor E2-related factor 2 (Nrf2) is considered an important factor in ferroptosis. Studies have d
Externí odkaz:
https://doaj.org/article/e345b36e37c14f7c904af54fb6ed460d
Autor:
Wenzhen Li, Yifan Wang, Xinbo Zhou, Xiaohong Pan, Junhong Lü, Hongliu Sun, Zeping Xie, Shayan Chen, Xue Gao
Publikováno v:
Journal of Ginseng Research, Vol 46, Iss 1, Pp 167-174 (2022)
Background: 20(S)-protopanaxadiol (20(S)-PPD), one of the main active metabolites of ginseng, performs a broad spectrum of anti-tumor effects. Our aims are to search out new strategies to enhance anti-tumor effects of natural products, including 20(S
Externí odkaz:
https://doaj.org/article/0914d197b5df4a409f7a609719711d97
Autor:
Lin Guo, Qiaoli Yang, Guangfei Wang, Shumin Zhang, Ming Liu, Xiaohong Pan, Gennaro Pescitelli, Zeping Xie
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Angucyclines and angucyclinones represent the largest family of type II PKS-engineered natural products. Chemical analysis of a marine Streptomyces sp. KCB-132 yielded three new members, actetrophenone A (1) and actetrophenols A–B (2–3). Their st
Externí odkaz:
https://doaj.org/article/da2974dae7da4fbbab2b8e7d6091435a
Autor:
Zeping Xie, Hui Lu, Sixia Yang, Yi Zeng, Wei Li, Linlin Wang, Guanfeng Luo, Fang Fang, Ting Zeng, Weidong Cheng
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Background: Alzheimer’s disease (AD) is a fatal neurodegenerative disease characterized by progressive cognitive decline and memory loss. However, several therapeutic approaches have shown unsatisfactory outcomes in the clinical setting. Thus, deve
Externí odkaz:
https://doaj.org/article/8cf44fb876114d7db85579c39252ab8f
Autor:
Lin Guo, Lu Zhang, Qiaoli Yang, Bo Xu, Xinzhen Fu, Ming Liu, Zhi Li, Shumin Zhang, Zeping Xie
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Chemical investigation of a marine-derived Streptomyces sp. KCB-132, cultivated in liquid ISP2 medium, had led to the discovery of three C-ring cleavage angucyclinone N-heterocycles, pratensilins A–C, with a novel spiro indolinone-naphthofuran skel
Externí odkaz:
https://doaj.org/article/e01989f5dbe84c8db448f3165aaec849
Autor:
Hartmut Laatsch, Naiyun Ji, Song Qin, Yipeng Wang, Hongyu Zhang, Shengxiang Yang, Hongpeng Wang, Zeping Xie, Bing Liu
Publikováno v:
Marine Drugs, Vol 10, Iss 3, Pp 551-558 (2012)
Kiamycin (1), a new angucyclinone derivative possessing an 1,12-epoxybenz[a]anthracene ring system, was isolated from the marine Streptomyces sp. strain M268 along with the known compounds 8-O-methyltetrangomycin (3) and 8-O-methylrabelomycin (4). Th
Externí odkaz:
https://doaj.org/article/8ea32197ed214cb49b79bb2acd144c0a
Autor:
Song Qin, Yang Pu, Zeping Xie, Hongli Cui, Zonggang Li, Hongpeng Wang, Fuchao Li, Hongyu Zhang
Publikováno v:
Marine Drugs, Vol 9, Iss 9, Pp 1502-1509 (2011)
A new anthracene derivative, 3-hydroxy-1-keto-3-methyl-8-methoxy-1,2,3,4-tetrahydro-benz[α]anthracene, was isolated from the marine strain Streptomyces sp. W007, and its structure was established by spectroscopic analysis including mass spectra, 1D-
Externí odkaz:
https://doaj.org/article/8dbca5608f9c453191c20dae9154d052