Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zephania W. Kwong"'
Autor:
Alavattam Sreedhara, Zephania W. Kwong Glover, Jennifer S. Laurence, Benjamin Moore, Louisette J. Basa
Publikováno v:
mAbs. 7:901-911
Fragmentation in the hinge region of an IgG1 monoclonal antibody (mAb) can affect product stability, potentially causing changes in potency and efficacy. Metals ions, such as Cu(2+), can bind to the mAb and undergo hydrolysis or oxidation, which can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aa6d5aca860c13dd9adf231304ef967
https://doi.org/10.1080/19420862.2015.1062193
https://doi.org/10.1080/19420862.2015.1062193
Autor:
Pin Yee Wong, Alavattam Sreedhara, Zephania W. Kwong Glover, Barthélemy Demeule, Sandeep Yadav, Lynn A. Gennaro
Publikováno v:
Journal of Pharmaceutical Sciences. 102:794-812
The physical/chemical stability and potential interactions after diluting two immunoglobulin G1 monoclonal antibodies (mAb), pertuzumab (Perjeta®) and trastuzumab (Herceptin®), in a single intravenous (i.v.) infusion bag containing 0.9% saline (NaC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6714bc3983e5e03e2bef06f409135482
https://doi.org/10.1002/jps.23403
https://doi.org/10.1002/jps.23403
Autor:
Nicole Piros, Nina Xiao, Alavattam Sreedhara, Bruce Kabakoff, Ankit R. Patel, Zephania W. Kwong Glover
Publikováno v:
Journal of Pharmaceutical Sciences. 101:21-30
Compounding pharmacists are expected to prepare safe and efficacious doses of medication under time and economical constraints while protecting pharmacy staff and caregivers from inadvertent exposure to the drug. The pharmacist has the additional res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff14be2728b239f31272e5af454e696
https://doi.org/10.1002/jps.22739
https://doi.org/10.1002/jps.22739
Publikováno v:
Journal of pharmaceutical sciences. 104(12)
Protein characterization is a necessary activity during development, technical transfers, and licensure. One important aspect of protein characterization is higher order structure assessment, which can be accomplished in a variety of ways. Circular d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a50ac6a814cd94847bb7cb73d13a08
https://pubmed.ncbi.nlm.nih.gov/26505267
https://pubmed.ncbi.nlm.nih.gov/26505267
Autor:
Paul Motchnik, Cynthia P. Quan, Yung-Hsiang Kao, Sirj Goswami, Ihsan Nijem, Reed J. Harris, Ryan Hutchinson, Xiangdan Wang, Tony Cano, Pin Yee Wong, Leslie A. Khawli, Zhenling Yao, Alavattam Sreedhara, Amita Joshi, Devin Tesar, Zephania W. Kwong, David E. Allison, Jihong Yang
Publikováno v:
mAbs. 2(6)
Antibody charge variants have gained considerable attention in the biotechnology industry due to their potential influence on stability and biological activity. Subtle differences in the relative proportions of charge variants are often observed duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d526532a75f03671636e5f1bd9dc1aa5
https://pubmed.ncbi.nlm.nih.gov/20818176
https://pubmed.ncbi.nlm.nih.gov/20818176
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