Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Zensho Ito"'
Autor:
Shizuka Suzuki, Kan Uchiyama, Yutaro Motoi, Yuuki Yoshii, Yukari Inoue, Takahiro Kubota, Shunichi Odahara, Yuichiro Ohtaki, Shinichiro Takami, Zensho Ito, Nobuhiro Sato, Toshifumi Ohkusa, Shigeo Koido, Masayuki Saruta
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Thiopurines continue to play an important role in the treatment of inflammatory bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. Especially, hematopoietic toxicity may lead to severe agra
Externí odkaz:
https://doaj.org/article/5ef338f38413497daa6f52c09275bbff
Autor:
Shigeo Koido, Sankichi Horiuchi, Shin Kan, Tsuuse Bito, Zensho Ito, Kan Uchiyama, Masayuki Saruta, Nobuhiro Sato, Toshifumi Ohkusa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Fusobacteria have been suspected to be pathobionts of colon cancer and inflammatory bowel disease. However, the immunomodulatory properties that affect these inflammatory reactions in dendritic cells (DCs) under anaerobic and aerobic conditi
Externí odkaz:
https://doaj.org/article/6598f3a5b34f4d25930735ece44eb223
Autor:
Sachie Kiryu, Zensho Ito, Machi Suka, Tsuuse Bito, Shin Kan, Kan Uchiyama, Masayuki Saruta, Taigo Hata, Yuki Takano, Shuichi Fujioka, Takeyuki Misawa, Takashi Yamauchi, Hiroyuki Yanagisawa, Nobuhiro Sato, Toshifumi Ohkusa, Haruo Sugiyama, Shigeo Koido
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Both activated tumor-infiltrating lymphocytes (TILs) and immune-suppressive cells, such as regulatory T cells (Tregs), in the tumor microenvironment (TME) play an important role in the prognosis of patients with pancreatic ductal
Externí odkaz:
https://doaj.org/article/8336055c81c24d62a8789f312e8859d7
Autor:
Yuichiro Ohtaki, Kan Uchiyama, Hirotaka Kamiya, Eri Moriizumi, Moe Yamada, Yuma Aoki, Toshimune Watanabe, Sachie Kiryu, Shizuka Suzuki, Yoshihiro Matsumoto, Zensho Ito, Toshifumi Ohkusa, Shigeo Koido, Masayuki Saruta
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d0a770709bd44b77bbdd1f31ca562dd0
Autor:
Sachie Kiryu, Zensho Ito, Masashi Ishikawa, Takafumi Akasu, Yoshihiro Matsumoto, Shinichi Hirooka, Masayuki Saruta, Shigeo Koido
Publikováno v:
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-4 (2020)
Abstract Introduction Pericardial effusion is a rare complication of pancreatic cancer. We report a case of cardiac tamponade secondary to pancreatic cancer. Case presentation A 68-year-old Japanese man was diagnosed as having pancreatic cancer durin
Externí odkaz:
https://doaj.org/article/15599d9f83df4f57be7d47bd77d2738e
Autor:
Zensho Ito, Shigeo Koido, Kumiko Kato, Toshitaka Odamaki, Sankichi Horiuchi, Takafumi Akasu, Masayuki Saruta, Taigo Hata, Yu Kumagai, Shuichi Fujioka, Takeyuki Misawa, Jin-zhong Xiao, Nobuhiro Sato, Toshifumi Ohkusa
Publikováno v:
Cancers, Vol 14, Iss 21, p 5379 (2022)
Characteristic bile duct and gut microbiota have been identified in patients with chronic biliary tract disease. This study aimed to characterize the fecal and bile microbiota in biliary tract cancer (BTC) patients and their relationship. Patients wi
Externí odkaz:
https://doaj.org/article/1dfbf5a884e54a3c91cc52f3daf14ce0
Autor:
Keisuke Saito, Shigeo Koido, Toshitaka Odamaki, Mikio Kajihara, Kumiko Kato, Sankichi Horiuchi, Sei Adachi, Hiroshi Arakawa, Sayumi Yoshida, Takafumi Akasu, Zensho Ito, Kan Uchiyama, Masayuki Saruta, Jin-Zhong Xiao, Nobuhiro Sato, Toshifumi Ohkusa
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212406 (2019)
Recent studies have suggested an association between certain members of the Fusobacterium genus, especially F. nucleatum, and the progression of advanced colorectal carcinoma (CRC). We assessed such an association of the gut microbiota in Japanese pa
Externí odkaz:
https://doaj.org/article/f8bc3ed2f04643e8b15e803d23466d52
Autor:
Zensho Ito, Mikio Kajihara, Yasunobu Kobayashi, Tomoya Kanai, Yoshihiro Matsumoto, Kazuki Takakura, Toyokazu Yukawa, Toshifumi Ohkusa, Seita Koyama, Hiroo Imazu, Hiroshi Arakawa, Mitsuru Ohata, Shigeo Koido
Publikováno v:
Case Reports in Gastroenterology, Vol 10, Iss 2, Pp 440-445 (2016)
Primary hepatic angiosarcoma is a very rare malignancy with a poor prognosis. Because patients present with no specific symptoms, the cancer can grow undetected and most cases are diagnosed too late for resection. We present the case of a 78-year-old
Externí odkaz:
https://doaj.org/article/afd21b62b62a42a39d02db6ada7bb4c5
Autor:
Shunichi Odahara, Kan Uchiyama, Takahiro Kubota, Zensho Ito, Shinichiro Takami, Hiroko Kobayashi, Keisuke Saito, Shigeo Koido, Toshifumi Ohkusa
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137798 (2015)
Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD). However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the precise mechanisms underlying thiopurine-related toxicity are
Externí odkaz:
https://doaj.org/article/6c61caf0adb64f12acf7f78299ad5109
Autor:
Kazuki Takakura, Yuichiro Shibazaki, Hiroyuki Yoneyama, Masato Fujii, Taishi Hashiguchi, Zensho Ito, Mikio Kajihara, Takeyuki Misawa, Sadamu Homma, Toshifumi Ohkusa, Shigeo Koido
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0142981 (2015)
Chondroitin sulfate E (CS-E), a highly sulfated glycosaminoglycan, is known to promote tumor invasion and metastasis. Because the presence of CS-E is detected in both tumor and stromal cells in pancreatic ductal adenocarcinoma (PDAC), multistage invo
Externí odkaz:
https://doaj.org/article/ba5c26a1fa7e47eb9fdc848fc6f18bc2