Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zenjiro Maruyama"'
Autor:
Carolina A Yoshida, Hisato Komori, Zenjiro Maruyama, Toshihiro Miyazaki, Keishi Kawasaki, Tatsuya Furuichi, Ryo Fukuyama, Masako Mori, Kei Yamana, Kouhei Nakamura, Wenguang Liu, Satoru Toyosawa, Takeshi Moriishi, Hiroshi Kawaguchi, Kenji Takada, Toshihisa Komori
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32364 (2012)
RUNX2 and SP7 are essential transcription factors for osteoblast differentiation at an early stage. Although RUNX2 inhibits osteoblast differentiation at a late stage, the function of SP7 at the late stage of osteoblast differentiation is not fully e
Externí odkaz:
https://doaj.org/article/e639d011c37e43edae07c19f4d69c22e
Autor:
Takeshi Moriishi, Zenjiro Maruyama, Ryo Fukuyama, Masako Ito, Toshihiro Miyazaki, Hideki Kitaura, Hidetake Ohnishi, Tatsuya Furuichi, Yosuke Kawai, Ritsuko Masuyama, Hisato Komori, Kenji Takada, Hiroshi Kawaguchi, Toshihisa Komori
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27487 (2011)
Bcl2 subfamily proteins, including Bcl2 and Bcl-X(L), inhibit apoptosis. As osteoblast apoptosis is in part responsible for osteoporosis in sex steroid deficiency, glucocorticoid excess, and aging, bone loss might be inhibited by the upregulation of
Externí odkaz:
https://doaj.org/article/2a5a87095d354acfbb744dbee1880200
Autor:
Hisato Komori, Kosei Ito, A Sakai, Hiroshi Kawaguchi, Toshihisa Komori, Takeshi Moriishi, Kenji Takada, Toshihiro Miyazaki, Zenjiro Maruyama, Carolina A. Yoshida, Shin-ichi Izumi
Publikováno v:
Oncogene. 33:1862-1871
Cell proliferation and differentiation are closely coupled. However, we previously showed that overexpression of cyclin-dependent kinase (Cdk6) blocks chondrocyte differentiation without affecting cell-cycle progression in vitro. To investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371960230ecb4b408ac99989d0de891e
https://doi.org/10.1038/onc.2013.130
https://doi.org/10.1038/onc.2013.130
Autor:
Kei Yamana, Toshihiro Miyazaki, Kozo Nakamura, Ryo Fukuyama, Toshihisa Komori, Norio Amizuka, Takeshi Moriishi, Masako Ito, Tatsuya Furuichi, Zenjiro Maruyama, Hiroshi Kawaguchi, Hideki Kitaura, Naoko Kanatani, Carolina A. Yoshida, Kouhei Nakamura, Takashi Fujita, Wenguang Liu
Publikováno v:
Developmental Dynamics. 236:1876-1890
Runx2 is an essential transcription factor for osteoblast differentiation. However, the functions of Runx2 in postnatal bone development remain to be clarified. Introduction of dominant-negative (dn)-Runx2 did not inhibit Col1a1 and osteocalcin expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf98925595cbaa32d210ee5f2751fef8
https://doi.org/10.1002/dvdy.21187
https://doi.org/10.1002/dvdy.21187
Autor:
Wataru Ogawa, Michihiro Matsumoto, Kazuto Hoshi, Satoru Kamekura, Hiroshi Kawaguchi, Ung-il Chung, Toru Akune, Zenjiro Maruyama, Kozo Nakamura, Takashi Kadowaki, Hirotaka Chikuda, Takashi Shimoaka, Yasuo Terauchi, Toshihisa Komori
Publikováno v:
Journal of Biological Chemistry. 279:15314-15322
Insulin receptor substrate-1 (IRS-1) is an essential molecule for intracellular signaling of insulin-like growth factor (IGF)-I and insulin, both of which are potent anabolic regulators of bone and cartilage metabolism. To investigate the role of IRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6a3ab0ae8c7c9dafea4f326f4e5a2f
https://doi.org/10.1074/jbc.m312525200
https://doi.org/10.1074/jbc.m312525200
Autor:
Hisato Komori, Satoru Toyosawa, Takeshi Moriishi, Masako Mori, Ryo Fukuyama, Tatsuya Furuichi, Toshihisa Komori, Kenji Takada, Carolina A. Yoshida, Keishi Kawasaki, Hiroshi Kawaguchi, Kouhei Nakamura, Wenguang Liu, Toshihiro Miyazaki, Zenjiro Maruyama, Kei Yamana
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e32364 (2012)
PLoS ONE, Vol 7, Iss 3, p e32364 (2012)
RUNX2 and SP7 are essential transcription factors for osteoblast differentiation at an early stage. Although RUNX2 inhibits osteoblast differentiation at a late stage, the function of SP7 at the late stage of osteoblast differentiation is not fully e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9ec58e2081890586552f8eae1b3163
https://pubmed.ncbi.nlm.nih.gov/22396760
https://pubmed.ncbi.nlm.nih.gov/22396760
Autor:
Zenjiro, Maruyama, Toshihisa, Komori
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e01d9e5d1cee8a48f301918df74acc45
https://pubmed.ncbi.nlm.nih.gov/18161086
https://pubmed.ncbi.nlm.nih.gov/18161086
Autor:
Kozo Nakamura, Shingo Sato, Takashi Shimoaka, Toshihisa Komori, Satoru Kamekura, Ung-il Chung, Kazuto Hoshi, Hirotaka Chikuda, Yosuke Kawasaki, Shu Takeda, Hiroshi Kawaguchi, Zenjiro Maruyama, Gerard Karsenty
Publikováno v:
Arthritis and rheumatism. 54(8)
Objective By producing instability in mouse knee joints, we attempted to determine the involvement of runt-related transcription factor 2 (RUNX-2), which is required for chondrocyte hypertrophy, in the development of osteoarthritis (OA). Methods An e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2694badbc637d4ac5f2a76453fb75891
https://pubmed.ncbi.nlm.nih.gov/16868966
https://pubmed.ncbi.nlm.nih.gov/16868966
Autor:
Kenji Takada, Ryo Fukuyama, Ritsuko Masuyama, Masako Ito, Hiroshi Kawaguchi, Toshihiro Miyazaki, Toshihisa Komori, Tatsuya Furuichi, Zenjiro Maruyama, Yosuke Kawai, Hisato Komori, Hideki Kitaura, Hidetake Ohnishi, Takeshi Moriishi
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27487 (2011)
PLoS ONE
PLoS ONE
Bcl2 subfamily proteins, including Bcl2 and Bcl-X(L), inhibit apoptosis. As osteoblast apoptosis is in part responsible for osteoporosis in sex steroid deficiency, glucocorticoid excess, and aging, bone loss might be inhibited by the upregulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e733f941379cc0a8d73f6241edf762a
http://hdl.handle.net/10069/26842
http://hdl.handle.net/10069/26842
Autor:
Zenjiro Maruyama, Carolina A. Yoshida, Tatsuya Furuichi, Norio Amizuka, Masako Ito, Ryo Fukuyama, Toshihiro Miyazaki, Hideki Kitaura, Kouhei Nakamura, Takashi Fujita, Naoko Kanatani, Takeshi Moriishi, Kei Yamana, Wenguang Liu, Hiroshi Kawaguchi, Kozo Nakamura, Toshihisa Komori
Publikováno v:
Developmental Dynamics; Jul2007, Vol. 236 Issue 7, p1876-1890, 15p