Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Zenichiro Kato"'
Autor:
Kozue Takano, Toshitaka Uchiyama, Noriko Otsuki, Hisahide Nishio, Yuji Kubo, Reiko Arakawa, Toshio Saito, Yasuhiro Takeshima, Kotaro Yuge, Toshio Ikeda, Zenichiro Kato, Takashi Nakajima, Kayoko Saito
Publikováno v:
Tokyo Women's Medical University Journal, Vol 6, Iss 0, Pp 57-66 (2022)
Background: Spinal muscular atrophy (SMA) is a lower motor neuron disease caused by SMN1. Several clinical trials have indicated that valproic acid (VPA) benefits a limited number of SMA patients. To clarify the difference in VPA responsiveness and e
Externí odkaz:
https://doaj.org/article/399e30eef3b84ac5bdc8bf62725691ef
Autor:
Tao Qin, Yanjun Jia, Yuhang Liu, Rongxin Dai, Lina Zhou, Satoshi Okada, Miyuki Tsumura, Hidenori Ohnishi, Zenichiro Kato, Hirokazu Kanegane, Xiulian Sun, Xiaodong Zhao
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Mutations in the IKBKB gene cause severe immunodeficiency, characterized clinically by persistent respiratory or gastrointestinal infections. Targeted gene panel sequencing revealed a novel homozygous missense mutation in the IKBKB gene of a patient
Externí odkaz:
https://doaj.org/article/f400aac5a12a4412a38c9895baf84596
Autor:
Hidenori Ohnishi, Norio Kawamoto, Hideo Kaneko, Kimiko Kasahara, Osamu Ohara, Zenichiro Kato, Toshiyuki Fukao
Publikováno v:
Allergology International, Vol 65, Iss 4, Pp 495-497 (2016)
Externí odkaz:
https://doaj.org/article/193e5db7a79b4e91a66e0b68892037e9
Autor:
Takahide Teramoto, Eiko Matsui, Toshiyuki Fukao, Kazuaki Sakai, Hiroshi Yonezawa, Zenichiro Kato, Hidenori Ohnishi, Hideo Kaneko, Naomi Kondo, Junichi Azuma, Sankei Nishima
Publikováno v:
Allergology International, Vol 61, Iss 4, Pp 619-624 (2012)
Background: Ciclesonide (CIC) is a highly safe, inhaled corticosteroid (ICS) that is converted into a pharmacologically active metabolite (des-isobutyryl-ciclesonide); this metabolite, in turn, exerts a local antiinflammatory effect on lung tissue. T
Externí odkaz:
https://doaj.org/article/f6ced461e99b477799615ec840497fd4
Autor:
Takeshi Kimura, Zenichiro Kato, Hidenori Ohnishi, Hidehito Tochio, Masahiro Shirakawa, Naomi Kondo
Publikováno v:
Allergology International, Vol 57, Iss 4, Pp 367-376 (2008)
Background: While interleukin-18 (IL-18) plays an important role in the innate and adaptive immune responses, it can also cause severe allergic inflammatory reactions. Thus it is a molecule currently being targeted for therapy. The natural intrinsic
Externí odkaz:
https://doaj.org/article/c5f0d679199f40828f1c04dde388e2cb
Autor:
Zenichiro Kato, Naomi Kondo
Publikováno v:
Allergology International, Vol 54, Iss 3, Pp 351-357 (2005)
Recent genomic studies have revealed many kinds of genetic polymorphisms. Some genetic polymorphisms have a correlation with allergic phenotypes, however there is only a statistical association without a precise molecular mechanism being demonstrated
Externí odkaz:
https://doaj.org/article/147ef23c63b64a6287d36115cd6b90a5
Autor:
Naomi Kondo, Eiko Matsui, Hideo Kaneko, Zenichiro Kato, Toshiyuki Fukao, Takahide Teramoto, Hiroaki Shikano, Minako Aoki, Hidenori Onishi, Koji Tatebayashi, Kentaro Omoya, Masashi Kondo, Eiji Matsukuma, Kimiko Kasahara, Naoko Morimoto
Publikováno v:
Allergology International, Vol 53, Iss 2, Pp 77-85 (2004)
Atopic disorders, such as asthma, eczema and rhinitis, develop due to the interactions between genetic and environmental factors. Atopy is characterized by enhanced IgE responses to environmental antigens. The production of IgE is upregulated by Th2
Externí odkaz:
https://doaj.org/article/e0b455618a5145f6b6f244332fe5dd49
Autor:
Hidenori Ohnishi, Hidehito Tochio, Zenichiro Kato, Norio Kawamoto, Takeshi Kimura, Kazuo Kubota, Takahiro Yamamoto, Tatsuyoshi Funasaka, Hiroshi Nakano, Richard W Wong, Masahiro Shirakawa, Naomi Kondo
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38423 (2012)
MyD88, a Toll/interleukin-1 receptor homology (TIR) domain-containing adaptor protein, mediates signals from the Toll-like receptors (TLR) or IL-1/IL-18 receptors to downstream kinases. In MyD88-dependent TLR4 signaling, the function of MyD88 is enha
Externí odkaz:
https://doaj.org/article/18e64eeb0aa94894ba179b361113d1e6
Publikováno v:
Pediatric Reports, Vol 1, Iss 1, Pp e9-e9 (2009)
The adverse effects or overdose of thioridazine including sudden death, fatal arrhythmia, or retinopathy, in addition to the neurological signs have been reported. A three-year-old boy with bronchitis was prescribed erythromycin by a local clinic, bu
Externí odkaz:
https://doaj.org/article/5a5c1c3200a5456fb5c28e0753a1de51
Autor:
Kento Inoue, Satoshi Miyamoto, Dan Tomomasa, Eriko Adachi, Shohei Azumi, Yasuo Horikoshi, Takashi Ishihara, Shinya Osone, Yuta Kawahara, Ko Kudo, Zenichiro Kato, Hidenori Ohnishi, Kenichi Kashimada, Kohsuke Imai, Osamu Ohara, Menno C. van Zelm, Morton J. Cowan, Tomohiro Morio, Hirokazu Kanegane
Publikováno v:
Journal of Clinical Immunology. 43:585-594
Artemis is an exonuclease essential for V(D)J recombination and repair of DNA double-stranded breaks. Pathogenic variants in DCLRE1C encoding Artemis cause TClinical data of ART-SCID patients who were diagnosed between 2003 and 2022 in Japan were col