Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zengxin Jiang"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Purpose Osteosarcoma is a primary bone tumor lacking optimal clinical treatment options. Tumor-associated macrophages in the tumor microenvironment are closely associated with tumor development and metastasis. Studies have identified the mac
Externí odkaz:
https://doaj.org/article/c5b10469f1af4024aa93ccf2b0a8fee0
Autor:
Zengxin Jiang, Guobin Qi, Xuecheng He, Yifan Yu, Yuting Cao, Changqing Zhang, Weiguo Zou, Hengfeng Yuan
Publikováno v:
Advanced Science, Vol 11, Iss 12, Pp n/a-n/a (2024)
Abstract Ferroptosis is a necrotic form of iron‐dependent regulatory cell death. Estrogen withdrawal can interfere with iron metabolism, which is responsible for the pathogenesis of postmenopausal osteoporosis (PMOP). Here, it is demonstrated that
Externí odkaz:
https://doaj.org/article/9728e9a6905b4123b5e6b1d87b44fcfc
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Despite extensive research, there is still a need for safe and effective agents to promote spinal fusion. Interleukin (IL)-1β is an important factor which influences the bone repair and remodelling. The purpose of our study was t
Externí odkaz:
https://doaj.org/article/35523622e31747f3b0019ae99e85b76d
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Targeting cartilage is a promising strategy for the treatment of osteoarthritis, and various delivery vehicles were developed to assist the therapeutic agents into cartilage. However, the underlying biomechanisms and potential bioactivities
Externí odkaz:
https://doaj.org/article/da6fdcab17084593ac47c192491295e4
Autor:
Jianfeng Pan, Meng Zhao, Xiangjiao Yi, Jianguo Tao, Shaobo Li, Zengxin Jiang, Biao Cheng, Hengfeng Yuan, Feng Zhang
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 272-287 (2022)
Peripheral nerve injury is a great challenge in clinical work due to the restricted repair gap and weak regrowth ability. Herein, we selected induced pluripotent stem cells (iPSCs) derived exosomes to supplement acellular nerve grafts (ANGs) with the
Externí odkaz:
https://doaj.org/article/426529d248cd44fabf60e593c5cb996b
Autor:
Guobin Qi, Zengxin Jiang, Wei Lu, Defang Li, Weibing Chen, Xiuying Yang, Lei Ding, Hengfeng Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteoporosis is a common public health problem characterized by decreased bone mass, increased bone brittleness and damage to the bone microstructure. Excessive bone resorption by osteoclasts is the main target of the currently used drugs or treatmen
Externí odkaz:
https://doaj.org/article/9c396324eb914bb3bdec2c8a2fec269e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteosarcoma (OS), the most common malignant tumor in the musculoskeletal system, mainly occurs in adolescents. OS results in high mortality and disability rates due to a fatal metastatic tendency and subsequent iatrogenic damage caused by surgery, r
Externí odkaz:
https://doaj.org/article/00e5391a17b9460a8f49e480fc7c0aeb
Autor:
Zengxin Jiang, Guobin Qi, Wei Lu, Hao Wang, Defang Li, Weibin Chen, Lei Ding, Xiuying Yang, Hengfeng Yuan, Qingmin Zeng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteoarthritis (OA) is a common degenerative joint disease. Effective drugs that can halt or decelerate osteoarthritis progression are still lacking. Omaveloxolone is a semisynthetic oleanane triterpenoid exerting antioxidative and anti-inflammatory
Externí odkaz:
https://doaj.org/article/abf4ec841a924c7da23083e4430ed899
Publikováno v:
IUBMB Life. 74:1052-1069
Growing evidence indicates that iron overload is an independent risk factor for osteoporosis. However, the mechanisms are not fully understood. The purpose of our study was to determine whether iron overload could lead to ferroptosis in osteoblasts a
Autor:
Yueqi Zhang, Guobin Qi, Yuheng Yan, Chenzhong Wang, Zhe Wang, Chang Jiang, Zengxin Jiang, Tianle Ma, Chi Zhang, Zuoqin Yan
Publikováno v:
The Journal of Gene Medicine.