Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Zengli Guo"'
Autor:
Gang Wang, Xiaowan Zhou, Zengli Guo, Nan Huang, Juan Li, Yanfang Lv, Lulu Han, Wei Zheng, Dandan Xu, Dafei Chai, Huizhong Li, Liantao Li, Junnian Zheng
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 150-162 (2022)
Transforming growth factor-β (TGF-β) plays a critical role in regulating cell growth and differentiation. Epithelial to mesenchymal transition (EMT) induced by TGF-β promotes cancer cell migration, invasion, and proliferation. Pirfenidone (5-methy
Externí odkaz:
https://doaj.org/article/73b030e57dbc4d289c244bb1a9138104
Autor:
Choudhury, Feroza K., Premkumar, Viji, Zecha, Jana, Boyd, Jonathan, Gaynor, Andrew S., Zengli Guo, Martin, Tom, Cimbro, Raffaello, Allman, Erik L., Hess, Sonja
Publikováno v:
Journal of Proteome Research; 8/2/2024, Vol. 23 Issue 8, p3096-3107, 12p
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pathogenic Th17 cells are critically involved in many autoimmune diseases, while non-pathogenic Th17 cells are more immune regulatory. Understanding the mechanisms of the induction and maintenance of pathogenic Th17 cells will benefit the development
Externí odkaz:
https://doaj.org/article/ef81a41648924f4382b5e61642dccaf5
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Foxp3 expressing regulatory T (Treg) cells, as the central negative regulator of adaptive immune system, are essential to suppress immune response and maintain immune homeostasis. However, the function of Treg cells is frequently compromised in autoi
Externí odkaz:
https://doaj.org/article/d099a3cdf1ef4f63b6ccdd3046ef31d6
Autor:
Zengli Guo, Qing Kong, Cui Liu, Song Zhang, Liyun Zou, Feng Yan, Jason K. Whitmire, Yue Xiong, Xian Chen, Yisong Y. Wan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
DCAF1 (VprBP), an HIV target protein, is a component of an ubiquitin ligase complex involved in developmental processes in plants and animals. Here, DCAF1 is shown to be vital for activation-induced T cell growth and proliferation, partly by being re
Externí odkaz:
https://doaj.org/article/e3ad2463a41e46ce80707481ab85705f
Autor:
Hui Tian, Dafei Chai, Gang Wang, Qiping Wang, Nan Sun, Guan Jiang, Huizhong Li, Jingyuan Song, Lin Fang, Meng Wang, Zengli Guo, Junnian Zheng
Publikováno v:
Cancer Immunology, Immunotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607d165df779e5098d455ab00b548667
https://doi.org/10.1007/s00262-023-03407-5
https://doi.org/10.1007/s00262-023-03407-5
Autor:
Xinyuan Wang, Juan Li, Ling Teng, Liantao Li, Wenwen Hu, Yuxin Chen, Huanyou Sun, Xuefan Yao, Zengli Guo, Yinan Yan, Gang Wang, Zichun Zhang, Dafei Chai, Junnian Zheng
Publikováno v:
Molecular Immunology. 139:184-192
Metastatic renal carcinoma is a kind of tumor with high degree of malignancy, but there are no effective treatment methods and strategies at present. In this study, we designed a folate-grafted PEI600-CyD (H1) nanoparticle-mediated DNA vaccine contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa4fa27b68d1def4f2f2a1930421c8a
https://doi.org/10.1016/j.molimm.2021.09.002
https://doi.org/10.1016/j.molimm.2021.09.002
Autor:
Junnian Zheng, Hui Tian, Gang Wang, Qiping Wang, Guan Jiang, Huizhong Li, Dafei Chai, Jingyuan Song, Lin Fang, Meng Wang, Zengli Guo
The metabolic stress present in tumors microenvironment (TME) attenuates T cells anti-tumor capacity, whereas the immune function of T cells is intrinsically controlled by their mitochondrial plasticity including mitochondrial dynamics, metabolism an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70fde631a0d1d5a69173ba251069873e
https://doi.org/10.21203/rs.3.rs-1394611/v1
https://doi.org/10.21203/rs.3.rs-1394611/v1
Autor:
Zengli Guo, Bing Wu, Gang Wang, Ge Zhang, Xiaojiang Xu, Yisong Y. Wan, Jian-liang Li, Junnian Zheng, Jason K. Whitmire
Publikováno v:
Cellular & Molecular Immunology. 18:2410-2421
Acute viral infection causes illness and death. In addition, an infection often results in increased susceptibility to a secondary infection, but the mechanisms behind this susceptibility are poorly understood. Since its initial identification as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be10e4c9ab01a1244dc203c29a66cfb
https://doi.org/10.1038/s41423-020-0495-7
https://doi.org/10.1038/s41423-020-0495-7
Autor:
Derek A. Franklin, Shijie Liu, Aiwen Jin, Pengfei Cui, Zengli Guo, Kyle C. Arend, Nathaniel J. Moorman, Shenghui He, Gang Greg Wang, Yisong Y. Wan, Yanping Zhang
Publikováno v:
Journal of Biological Chemistry. 299:102739
Recent discovery of the ribosomal protein (RP) RPL11 interacting with and inhibiting the E3 ubiquitin ligase function of MDM2 established the RP-MDM2-p53 signaling pathway, which is linked to biological events, including ribosomal biogenesis, nutrien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9493f596c936624e55ee696b58b69bbc
https://doi.org/10.1016/j.jbc.2022.102739
https://doi.org/10.1016/j.jbc.2022.102739