Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zenglan Li"'
Publikováno v:
Remote Sensing, Vol 15, Iss 12, p 3197 (2023)
The crop drought risk assessment is an important basis for mitigating the effects of drought on crops. The study of drought using crop growth models is an integral part of agricultural drought risk research. The current Decision Support System for Ag
Externí odkaz:
https://doaj.org/article/333080fb23054ff78b4af2c3ddbe3931
Publikováno v:
Remote Sensing; Volume 15; Issue 12; Pages: 3197
The crop drought risk assessment is an important basis for mitigating the effects of drought on crops. The study of drought using crop growth models is an integral part of agricultural drought risk research. The current Decision Support System for Ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::af8d33082082c03958fac6da951389d1
Publikováno v:
Biochemical Engineering Journal. 172:108055
Recombinant human interferon β-1b (rhIFN β-1b) represents a highly hydrophobic protein and is difficult to refold from inclusion bodies (IBs) using conventional methods. In this paper, we report a strategy of high hydrostatic pressure (HHP) combini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdad192de202cb50429714ea20c2185e
https://doi.org/10.1016/j.bej.2021.108055
https://doi.org/10.1016/j.bej.2021.108055
Publikováno v:
Process Biochemistry. 62:80-90
Production of natural pertactin for pharmaceutical use is limited by its low abundance. In this study, recombinant pertactin was highly expressed in the form of inclusion bodies in E. coli . However, up to 75% of the soluble turned out as aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b07471b0fc525121f47e88761b7d0a
https://doi.org/10.1016/j.procbio.2017.07.001
https://doi.org/10.1016/j.procbio.2017.07.001
Publikováno v:
Bioconjugate Chemistry. 28:2841-2848
In this paper, we reported a novel strategy for the site-specific attachment of polyethylene glycol (PEGylation) of proteins using elevated hydrostatic pressure. The process was similar to the conventional one except the reactor was under elevated hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be7ab3fc702423bd3628b4d34b0b1f7
https://doi.org/10.1021/acs.bioconjchem.7b00531
https://doi.org/10.1021/acs.bioconjchem.7b00531
Autor:
Jingxiu Bi, Chun Zhang, Rong Yu, Liping Liu, Shuang Yin, Zhiguo Su, Chunyue Wang, Qi Wang, Yongdong Liu, Zenglan Li
Publikováno v:
Molecular Pharmaceutics. 14:3739-3749
For the purpose of improving the tumor delivery of doxorubicin (DOX), a kind of peptide-DOXO conjugate was designed and prepared, in which the peptide composed of an albumin-binding domain (ABD) and a tumor-specific internalizing sequence (RGDK or RP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e35b12ee7eee6e42620fe4e127e30c1
https://doi.org/10.1021/acs.molpharmaceut.7b00497
https://doi.org/10.1021/acs.molpharmaceut.7b00497
Publikováno v:
Reactive and Functional Polymers. 117:97-105
Site-specific PEGylation of clinically used protein via free cysteine residue has been widely applied for a homogeneous product. Herein, we described a new thiol-specific PEGylation strategy based on catechol-derived reactive quinone species. Catecho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::934b2e76e801d8ef4c0b446ff03b9088
https://doi.org/10.1016/j.reactfunctpolym.2017.06.005
https://doi.org/10.1016/j.reactfunctpolym.2017.06.005
Publikováno v:
International Journal of Pharmaceutics. 529:275-284
To overcome the deficiency of rapid elimination from blood, the truncated human recombinant ciliary neurotrophic factor was formulated by site-specific attachment of different-sized PEG-maleimide or by cross-linking with human transferrin through a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acebd4bbb083e808dcac9a4c49f99a90
https://doi.org/10.1016/j.ijpharm.2017.06.074
https://doi.org/10.1016/j.ijpharm.2017.06.074
Autor:
Yongdong Liu, Jian Luo, Zhiguo Su, Qi Wang, Liping Liu, Chun Zhang, Xiunan Li, Fangxia Guo, Dawei Zhao, Zenglan Li
Publikováno v:
Journal of Biotechnology. 254:34-42
Human ferritin (HFn) nanocaging is becoming an appealing platform for anticancer drugs delivery. However, protein aggregation always occurs during the encapsulation process, resulting in low production efficiency. A new approach using high hydrostati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18e6a9b91458329418d7d500344dd44
https://doi.org/10.1016/j.jbiotec.2017.05.025
https://doi.org/10.1016/j.jbiotec.2017.05.025
Publikováno v:
Process Biochemistry. 53:216-223
A kind of degradation characterized by an increase in overall negative charge in both native polyacrylamide gel electrophoresis analysis and high-performance strong anion exchange analysis was observed during the purification process of recombinant h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff33a47a4b3f2d3ca0bacb74ac721b3b
https://doi.org/10.1016/j.procbio.2016.11.011
https://doi.org/10.1016/j.procbio.2016.11.011