Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zengbing Bai"'
Autor:
Chuangxu Cai, Feifei Wang, Xiuyun Xiao, Wangjian Sheng, Shu Liu, Jun Chen, Jie Zheng, Ran Xie, Zengbing Bai, Huan Wang
Publikováno v:
Chemical Communications. 58:4861-4864
A method is developed for modification and macrocyclization of thiazole-containing peptides through palladium-catalyzed δ-C(sp2)–H olefination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478ae95f1c4108016dc08631b8c07a99
https://doi.org/10.1039/d1cc06764h
https://doi.org/10.1039/d1cc06764h
Autor:
Zengbing Bai, Qingqing Chen, Jun Gu, Chuangxu Cai, Jie Zheng, Wangjian Sheng, Shandong Yi, Fang Liu, Huan Wang
Publikováno v:
ACS Catalysis. 11:15125-15134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152bbf659ff5a1f23f4b25e58efc5dcc
https://doi.org/10.1021/acscatal.1c05030
https://doi.org/10.1021/acscatal.1c05030
Publikováno v:
Organic Letters. 23:2933-2937
Oxazole is an important pharmacophore and exists in the backbone of many bioactive peptide natural products and peptidomimetics. Efficient methods for the synthesis and direct functionalization of complex oxazole-containing peptides are in high deman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f914c6492fe19636b3c6943fd175784e
https://doi.org/10.1021/acs.orglett.1c00580
https://doi.org/10.1021/acs.orglett.1c00580
Publikováno v:
Natural Product Reports. 38:981-992
Covering: 2000 to 2020 Ribosomally synthesized and posttranslational modified peptides (RiPPs) are a rapidly growing class of bioactive natural products. Many members of RiPPs contain macrocyclic structural units constructed by modification enzymes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708692c4b325f5e3a15e110eea7e2d28
https://doi.org/10.1039/d0np00044b
https://doi.org/10.1039/d0np00044b
Publikováno v:
Angewandte Chemie. 132:14794-14800
Transition-metal-catalyzed C-H activation has shown potential in the functionalization of peptides with expanded structural diversity. Herein, the development of late-stage peptide macrocyclization methods by palladium-catalyzed site-selective C(sp2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d543353a4c7d7c058d730edba6b76aa
https://doi.org/10.1002/ange.202007226
https://doi.org/10.1002/ange.202007226
Autor:
Zengbing Bai, Huan Wang
Publikováno v:
Synlett. 31:199-204
Peptide macrocycles are widely used in fields ranging from medicinal chemistry to materials science. Efficient chemical methods for the synthesis of cyclic peptides with novel three-dimensional structures are highly desired to facilitate the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b76fe413294e7053c756b72b30123c7
https://doi.org/10.1055/s-0039-1691495
https://doi.org/10.1055/s-0039-1691495
Publikováno v:
Organic Letters. 21:8225-8228
Macrocyclic peptides are promising scaffolds of bioactive compounds and clinical therapeutics. Herein, we develop a strategy for the macrocyclization of biaryl-bridged peptides through late-stage Pd-catalyzed C(sp2)-H arylation. This method displays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44eec975cb211ef2acb137f98e2c057a
https://doi.org/10.1021/acs.orglett.9b02945
https://doi.org/10.1021/acs.orglett.9b02945
Publikováno v:
Natural product reports. 38(5)
Covering: 2000 to 2020 Ribosomally synthesized and posttranslational modified peptides (RiPPs) are a rapidly growing class of bioactive natural products. Many members of RiPPs contain macrocyclic structural units constructed by modification enzymes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ae1a2241c377359793e8794697d4a4d
https://pubmed.ncbi.nlm.nih.gov/33185226
https://pubmed.ncbi.nlm.nih.gov/33185226
Autor:
Zengbing Bai, Huan Wang, Yingying Zhang, Yuqing Li, Jingxia Lu, Jiapeng Zhu, Jie Zheng, Jiao Li, Yuan Wu
Thioamitides are a group of ribosomally synthesized and post-translational modified peptides with potent antiproliferative and pro-apoptotic activities. Their biosynthesis remains largely unknown, especially for the characteristic C-terminal 2-aminov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce9ecc5a4d295dcd83c43ffdbfb3e72
https://doi.org/10.1101/2020.08.21.260323
https://doi.org/10.1101/2020.08.21.260323
Publikováno v:
Angewandte Chemie International Edition. 57:13912-13916
C-H activation methods for peptide macrocyclization have the potential to provide peptidomimetics and cyclic peptides with expanded structural diversity. Now, a highly versatile peptide macrocyclization strategy via late-stage palladium-catalyzed δ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c499f25177b3ddf43c59e8f9357355
https://doi.org/10.1002/anie.201807953
https://doi.org/10.1002/anie.201807953