Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Zeng-Jin Yang"'
Autor:
Christopher T. Primiani, Jennifer K. Lee, Caitlin E. O’Brien, May W. Chen, Jamie Perin, Ewa Kulikowicz, Polan Santos, Shawn Adams, Bailey Lester, Natalia Rivera-Diaz, Valerie Olberding, Mark V. Niedzwiecki, Eva K. Ritzl, Christa W. Habela, Xiuyun Liu, Zeng-Jin Yang, Raymond C. Koehler, Lee J. Martin
Publikováno v:
Cells, Vol 12, Iss 20, p 2454 (2023)
The effects of hypothermia on neonatal encephalopathy may vary topographically and cytopathologically in the neocortex with manifestations potentially influenced by seizures that alter the severity, distribution, and type of neuropathology. We develo
Externí odkaz:
https://doaj.org/article/ae0556a118e641cd9a3b614c725aad53
Autor:
Ranran Han, Jieru Wan, Xiaoning Han, Honglei Ren, John R. Falck, Sailu Munnuri, Zeng-Jin Yang, Raymond C. Koehler
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Intracerebral hemorrhage (ICH) is a highly fatal type of stroke that leads to various types of neuronal death. Recently, ferroptosis, a form of cell death resulting from iron-dependent lipid peroxide accumulation, was observed in a mouse ICH model. N
Externí odkaz:
https://doaj.org/article/55de5826e0c9473c9899c4cdf2c5f2fe
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 2, Pp 446-454 (2011)
Na+,Ca2+-permeable acid-sensing ion channel 1a (ASIC1a) is involved in the pathophysiologic process of adult focal brain ischemia. However, little is known about its role in the pathogenesis of global cerebral ischemia or newborn hypoxia–ischemia (
Externí odkaz:
https://doaj.org/article/5603426667e84f20ae20675ab615227f
Publikováno v:
Neonatology. 119:354-360
Introduction: Striatal neurons of term newborns are highly vulnerable to hypoxia-ischemia (H-I). In a piglet model of H-I, a dopamine D1 receptor antagonist and an adenosine A2A receptor antagonist alone preferentially protect striatonigral and stria
Autor:
Wenzhu Wang, Haigang Li, Jintao Yu, Michael Hong, Jing Zhou, Lin Zhu, Yang Wang, Min Luo, Zian Xia, Zeng-Jin Yang, Tao Tang, Ping Ren, Xi Huang, Jian Wang
Publikováno v:
Molecular Neurobiology. 60:1746-1747
Publikováno v:
Dev Neurosci
The striatal, primary sensorimotor cortical, and thalamic neurons are highly vulnerable to hypoxia-ischemia (HI) in term newborns. In a piglet model of HI that exhibits similar selective regional vulnerability, we tested the hypothesis that early tre
Autor:
John R. Falck, Xiaofan Zhang, Zeng Jin Yang, Nagat El Demerdash, Raymond C. Koehler, Sailu Munnuri
Publikováno v:
Prostaglandins & Other Lipid Mediators. 137:63-68
20-Hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P450 (CYP) 4A/4F-derived metabolite of arachidonic acid, directly contributes to ischemic neuronal injury. However, little is known about mediators of 20-HETE neurotoxicity after ischemia. Here,
Autor:
Raymond C. Koehler, Jian Wang, Xi Liu, John R. Falck, Austin M. Guo, Xiaoning Han, Zeng-Jin Yang, Xiaochun Zhao, Qian Li, Jieru Wan, Yufeng Gao, Weidong Zang, Xi Lan, Xuemei Chen
Publikováno v:
J Cereb Blood Flow Metab
20-HETE, an arachidonic acid metabolite synthesized by cytochrome P450 4A, plays an important role in acute brain damage from ischemic stroke or subarachnoid hemorrhage. We tested the hypothesis that 20-HETE inhibition has a protective effect after i
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Autor:
Zeng-Jin Yang, Ewa Kulikowicz, C. Danielle Hopkins, Shawn Adams, Harikrishna Tandri, Raymond C. Koehler
Publikováno v:
Circulation. 140
Introduction: High transnasal airflow at ambient temperature increases evaporative cooling of the nasal passages and drives a countercurrent heat exchange between cooled venous blood draining the nasal turbinates with cephalic arterial blood. Hypothe