Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zeng B, Zhu"'
Autor:
Kristopher J. Kimball, Angel A. Rivera, Kurt R. Zinn, Mert Icyuz, Vaibhav Saini, Jing Li, Zeng B. Zhu, Gene P. Siegal, Joanne T. Douglas, David T. Curiel, Ronald D. Alvarez, Anton V. Borovjagin
Publikováno v:
Molecular Imaging, Vol 8 (2009)
We sought to develop a cancer-targeted, infectivity-enhanced oncolytic adenovirus that embodies a capsid-labeling fusion for non-invasive dual-modality imaging of ovarian cancer virotherapy. A functional fusion protein composed of fluorescent and nuc
Externí odkaz:
https://doaj.org/article/80e945348aad45c5b929bba0299c9446
Publikováno v:
Clinical and Translational Medicine
Background Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation. Aim To select a potent radiation inducible promoter in the
Autor:
Yu Han, Ilya V. Ulasov, Suvobroto Nandi, Matthew A. Tyler, Zeng B. Zhu, Luciana Molinero, Adam Quasar Sugihara, Maciej S. Lesniak
Publikováno v:
Cancer Research. 68:5778-5784
To improve the efficacy and selectivity of virotherapy for malignant glioma, we designed a strategy to amplify adenoviral replication in conjunction with radiotherapy using a radioinducible promoter. First, we compared the radiation-inducible activit
Publikováno v:
Journal of Neurosurgery. 107:617-627
Object Gene therapy protocols for malignant gliomas utilize adenoviral vectors that rely almost exclusively on the adenovirus serotype 5 (Ad5) backbone. The authors have previously shown that chimeric vectors that bind to the Ad3 receptor, or CD46, i
Autor:
Andrey Khramtsov, Maciej S. Lesniak, Yun Han, Zeng B. Zhu, Matthew A. Tyler, Ilya V. Ulasov, Angel A. Rivera, David T. Curiel
Publikováno v:
Human Gene Therapy. 18:589-602
The poor prognosis of patients with malignant gliomas necessitates the development of novel therapies. Virotherapy, using genetically engineered adenovectors that selectively replicate in and kill neoplastic cells, represents one such strategy. In th
Autor:
Ilya V. Ulasov, Angel A. Rivera, Adam M. Sonabend, Ming Wang, Zeng B. Zhu, Maciej S. Lesniak, Lisa B. Rivera
Publikováno v:
Cancer Biology & Therapy. 6:679-685
Transcriptional targeting is a key strategy to enhance therapeutic efficacy of gene therapy applications. In the context of oncolytic virotherapy, transcriptional promoter elements are used from genes that are over expressed in a variety of malignant
Autor:
Zeng B. Zhu, Robert J. Cerfolio, Sharmila K. Makhija, Miiru Izumi, Baogen Lu, Fen Zhou, Koichi Takayama, David T. Curiel, Mariam A. Stoff-Khalili, Minghui Wang, Gene P. Siegal, Angel A. Rivera
Publikováno v:
Lung Cancer. 55:145-156
Conventional treatments are not adequate for the majority of lung cancer patients. Conditionally replicating adenoviruses (CRAds) represent a promising new modality for the treatment of neoplastic diseases, including non-small cell lung cancer. Speci
Autor:
Amanda S Moon, Louise T. Chow, David T. Curiel, Mariam A. Stoff-Khalili, Peter Dall, Larissa Pereboeva, Rodney P. Rocconi, Gene P. Siegal, J. Michael Mathis, Hans Georg Bender, N. Sanjib Banerjee, Zeng B. Zhu, Alexander Stoff, Angel A. Rivera, Joanne T. Douglas, Alexandra P. Hess, Maaike Everts, T. Michael Numnum
Publikováno v:
Breast Cancer Research and Treatment. 105:157-167
Alternative and complementary therapeutic strategies need to be developed for metastatic breast cancer. Virotherapy is a novel therapeutic approach for the treatment of cancer in which the replicating virus itself is the anticancer agent. However, th
Publikováno v:
Encyclopedia of Cancer ISBN: 9783642278419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c06f0c2bfdf56a02d45b9db864aca5
https://doi.org/10.1007/978-3-642-27841-9_6197-3
https://doi.org/10.1007/978-3-642-27841-9_6197-3