Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Zenda Woodman"'
Autor:
Evelyn Ngwa Lumngwena, Simon Metenou, Lindi Masson, Claudia Cicala, James Arthos, Zenda Woodman
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Heterosexual transmission remains the main route of HIV-1 transmission and female genital tract (FGT) inflammation increases the risk of infection. However, the mechanism(s) by which inflammation facilitates infection is not fully
Externí odkaz:
https://doaj.org/article/e1117f96e80948e6aea72779e2b5a403
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Objective As part of a larger study to understand how Envelope N-glycosylation influences HIV-1 pathogenesis, we selected a participant infected with a single Subtype C variant and determined whether deletion of specific potential N-glycan s
Externí odkaz:
https://doaj.org/article/91155e4f28384c80850daecc25ff02f5
Autor:
Evelyn Ngwa Lumngwena, Bianca Abrahams, Liliwe Shuping, Claudia Cicala, James Arthos, Zenda Woodman
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227533 (2020)
Envelope (Env) phenotype(s) that provide transmitted founders (TF) with a selective advantage during HIV-1 transmission would be the ideal target for preventative therapy. We generated Env clones from four individuals infected with a single virus and
Externí odkaz:
https://doaj.org/article/c5f4b953ec4943e6a81c0bc630e3d17e
Autor:
Denis R Chopera, Zenda Woodman, Koleka Mlisana, Mandla Mlotshwa, Darren P Martin, Cathal Seoighe, Florette Treurnicht, Debra Assis de Rosa, Winston Hide, Salim Abdool Karim, Clive M Gray, Carolyn Williamson, CAPRISA 002 Study Team
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000033 (2008)
One of the most important genetic factors known to affect the rate of disease progression in HIV-infected individuals is the genotype at the Class I Human Leukocyte Antigen (HLA) locus, which determines the HIV peptides targeted by cytotoxic T-lympho
Externí odkaz:
https://doaj.org/article/c930c4d75daf4947b374aacfb0fc4d67
Autor:
Claudia Cicala, Simon Metenou, James Arthos, Zenda Woodman, Lindi Masson, Evelyn Ngwa Lumngwena
Publikováno v:
Retrovirology
Retrovirology, Vol 17, Iss 1, Pp 1-13 (2020)
Retrovirology, Vol 17, Iss 1, Pp 1-13 (2020)
Background Heterosexual transmission remains the main route of HIV-1 transmission and female genital tract (FGT) inflammation increases the risk of infection. However, the mechanism(s) by which inflammation facilitates infection is not fully understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab504bd9480376f1cc5f277f7deca01
http://europepmc.org/articles/PMC7331269
http://europepmc.org/articles/PMC7331269
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Objective As part of a larger study to understand how Envelope N-glycosylation influences HIV-1 pathogenesis, we selected a participant infected with a single Subtype C variant and determined whether deletion of specific potential N-glycan sites (PNG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a39640f61da1045a595425e2a8494c2
http://europepmc.org/articles/PMC6580609
http://europepmc.org/articles/PMC6580609
Autor:
Zenda Woodman, Kerry Gordon, Andile Nofemela, Carolyn Williamson, Gama Bandawe, Shatha Sultan Omar
Publikováno v:
AIDS Research and Human Retroviruses. 32:303-310
Mutations in functionally constrained sites of the HIV envelope (Env) can affect entry efficiency and are potential targets for vaccine and drug design. We investigated Du151, a dual-infected individual with rapid disease progression. At her death 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c8526f27ed821f2083def5679a982d
https://doi.org/10.1089/aid.2014.0100
https://doi.org/10.1089/aid.2014.0100
Autor:
Bruce D. Walker, Zenda Woodman, Debra de Assis Rosa, Jonathan M. Carlson, Zabrina L. Brumme, Nobubelo K. Ngandu, Salim S. Abdool Karim, Roman Ntale, Koleka Mlisana, Denis Chopera, Eric Martin, Clive M. Gray, Toshiyuki Miura, Alexander Zawaira, Thumbi Ndung'u, Carolyn Williamson, Mark A. Brockman, Florencia Pereyra, Laura A. Cotton, Darren P. Martin, Jaclyn K. Mann
Publikováno v:
Journal of Virology. 86:13423-13433
Certain immune-driven mutations in HIV-1, such as those arising in p24 Gag , decrease viral replicative capacity. However, the intersubtype differences in the replicative consequences of such mutations have not been explored. In HIV-1 subtype B, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e10d23b5716fd665a787531dc9c1b9
https://doi.org/10.1128/jvi.02171-12
https://doi.org/10.1128/jvi.02171-12
Autor:
Francesca Little, Jo-Ann S. Passmore, Salim S. Abdool Karim, Quarraisha Abdool Karim, Zenda Woodman, Carolyn Williamson, Lisa M. Bebell, Melissa-Rose Abrahams, Lindi Roberts, Koleka Mlisana, Gerhard Walzl
Publikováno v:
The Journal of Infectious Diseases. 205:194-203
In sub-Saharan Africa, which has the highest prevalence of human immunodeficiency virus type 1 (HIV-1) worldwide, most new infections occur by sexual transmission to women [1]. The genital mucosa is the initial site of viral replication following vag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90caf31824dc433029261a056a4dcb4
https://doi.org/10.1093/infdis/jir715
https://doi.org/10.1093/infdis/jir715
Autor:
Salim S. Abdool Karim, Carolyn Williamson, Ruwayida. Thebus, Melissa-Rose Abrahams, Zenda Woodman, Florette K. Treurnicht, Koleka Mlisana
Publikováno v:
AIDS Research and Human Retroviruses. 27:1167-1172
Previously, we determined the incidence of dual infections in a South African cohort and its association with higher viral setpoint. Ten years later, we compare the incidence and impact of dual infections at transmission on viral setpoint in a geogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e6043dfe7c8542a3799fadef5e7074
https://doi.org/10.1089/aid.2010.0162
https://doi.org/10.1089/aid.2010.0162