Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zena N. Willsmore"'
Autor:
Silvia Crescioli, Isabel Correa, Joseph Ng, Zena N. Willsmore, Roman Laddach, Alicia Chenoweth, Jitesh Chauhan, Ashley Di Meo, Alexander Stewart, Eleni Kalliolia, Elena Alberts, Rebecca Adams, Robert J. Harris, Silvia Mele, Giulia Pellizzari, Anna B. M. Black, Heather J. Bax, Anthony Cheung, Mano Nakamura, Ricarda M. Hoffmann, Manuela Terranova-Barberio, Niwa Ali, Ihor Batruch, Antoninus Soosaipillai, Ioannis Prassas, Antigona Ulndreaj, Miyo K. Chatanaka, Rosamund Nuamah, Shichina Kannambath, Pawan Dhami, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Anita Grigoriadis, David Kipling, Panagiotis Karagiannis, Deborah K. Dunn-Walters, Eleftherios P. Diamandis, Sophia Tsoka, James Spicer, Katie E. Lacy, Franca Fraternali, Sophia N. Karagiannis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract B cells are known to contribute to the anti-tumor immune response, especially in immunogenic tumors such as melanoma, yet humoral immunity has not been characterized in these cancers to detail. Here we show comprehensive phenotyping in sampl
Externí odkaz:
https://doaj.org/article/ec79417fc51f4749a49432bb35eb4eff
Autor:
Akshay J. Patel, Zena N. Willsmore, Naeem Khan, Alex Richter, Babu Naidu, Mark T. Drayson, Sophie Papa, Andrew Cope, Sophia N. Karagiannis, Esperanza Perucha, Gary W. Middleton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Immune checkpoint blockade is a promising approach to treat lung cancer, however, immune related adverse events hold back success in some patients. Here authors show that regulatory B cells fail to limit self-reactive T cells in these patients, and B
Externí odkaz:
https://doaj.org/article/c2085253ca8c457fb16c85cb9930af88
Autor:
Zena N. Willsmore, Robert J. Harris, Silvia Crescioli, Khuluud Hussein, Helen Kakkassery, Deepika Thapa, Anthony Cheung, Jitesh Chauhan, Heather J. Bax, Alicia Chenoweth, Roman Laddach, Gabriel Osborn, Alexa McCraw, Ricarda M. Hoffmann, Mano Nakamura, Jenny L. Geh, Alastair MacKenzie-Ross, Ciaran Healy, Sophia Tsoka, James F. Spicer, Sophie Papa, Linda Barber, Katie E. Lacy, Sophia N. Karagiannis
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The contributions of the humoral immune response to melanoma are now widely recognized, with reports of positive prognostic value ascribed to tumor-infiltrating B cells (TIL-B) and increasing evidence of B cells as key predictors of patient response
Externí odkaz:
https://doaj.org/article/ed0d67dd841b4bf0be26df03605f653b
Autor:
Alistair Robson, R.J. Barlow, Mina Ally, Werner Kempf, Ellie Rashidghamat, Zena N Willsmore, Ben Esdaile, Farrah Bakr, Danielle Greenblatt, Fiona Child, E. Mary Wain
Publikováno v:
The American Journal of dermatopathology. 43(12)
Introduction Primary cutaneous marginal zone B-cell lymphoma (MZL) follows an indolent clinical course. Histopathologically, there is a polymorphous infiltrate that includes small lymphocyte-like and centrocyte-like B cells and plasma cells usually w
Autor:
Alistair Robson, Zena N Willsmore
Publikováno v:
Melanoma in Clinical Practice ISBN: 9783030826383
Melanoma in Clinical Practice
Melanoma in Clinical Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db501dad1f05be00bc709c5f92645f46
https://doi.org/10.1007/978-3-030-82639-0_4
https://doi.org/10.1007/978-3-030-82639-0_4
Autor:
Alexa McCraw, Alastair MacKenzie-Ross, Jitesh Chauhan, James Spicer, Zena N Willsmore, Sara Reci, Ricarda M. Hoffmann, Mano Nakamura, Anthony Cheung, Sophia N. Karagiannis, Silvia Crescioli, Sophie Papa, Heather J. Bax, Debra H. Josephs, Alicia Chenoweth, Sophia Tsoka, Ciaran Healy, Ayushi Gupta, Jenny L. C. Geh, Gabriel Osborn, Katie E. Lacy, Robert J. Harris, Roman Laddach, Ben G T Coumbe
Publikováno v:
European journal of immunologyReferences. 51(3)
Cytotoxic T-lymphocyte associated protein-4 (CTLA-4) and the Programmed Death Receptor 1 (PD-1) are immune checkpoint molecules that are well-established targets of antibody immunotherapies for the management of malignant melanoma. The monoclonal ant