Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Zen-yo Tanakamaru"'
Autor:
Yasuyuki Awasaki, Masaki Yamamoto, Hirofumi Nagai, Keiichiro Sato, Zen-yo Tanakamaru, Hitoshi Kandori, David Baron
Publikováno v:
Toxicology and Applied Pharmacology. 251:234-244
Pioglitazone hydrochloride (PIO), a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, was administered orally for 85 weeks at 16 mg/kg/day to male rats fed either a diet containing 1.5% ammonium chloride (acid-forming diet) or a cont
Autor:
Masaya Takaoka, Shinya Sehata, Takanori Maejima, Toshio Imai, Mikinori Torii, Hiroshi Satoh, Kaoru Toyosawa, Zen-yo Tanakamaru, Tamiko Adachi, Shigeru Hisada, Makoto Ueda, Hiroyuki Ogasawara, Masahiro Matsumoto, Kiyoshi Kobayashi, Mamoru Mutai, Toshimi Usui
Publikováno v:
Toxicologic Pathology. 31:191-199
Autor:
Hiroshi Kanno, Yoshimasa Ishimura, Satoshi Sasaki, Zen-yo Tanakamaru, Hideki Yamasaki, Hitoshi Kandori
Publikováno v:
Journal of Toxicologic Pathology. 16:267-274
CB6F1-TgHras2 mice (rasH2 mice) are considered to be a promising model for short-term carcinogenicity studies. This study was conducted to obtain background data for rasH2 mice, and the data were compared with those for CB6F1-nonTgHras2 mice (nonTg m
Autor:
Ken-ichiro Kasahara, Takayoshi Imazawa, Akiyoshi Nishikawa, Takako Ikeda, Masao Hirose, Zen-yo Tanakamaru, Fumio Furukawa, Hideaki Nakamura, Makoto Miyauchi
Publikováno v:
Cancer Letters. 141:109-115
The chemopreventive influence of phenethyl isothiocyanate (PEITC) during the post-initiation stage was investigated in the N-nitrosobis(2-oxopropyl)amine (BOP)-initiated hamster tumorigenesis model. A total of 120 female 5-week-old hamsters were divi
Autor:
Hideaki Nakamura, Akiyoshi Nishikawa, Fumio Furukawa, Masao Hirose, Hideki Mori, Zen-yo Tanakamaru, Shinichiro Ikezaki
Publikováno v:
The Journal of Toxicological Sciences. 24:133-139
In order to examine the influences by long-term feeding of 24R, 25 dihydroxyvitamin D3[24R, 25(OH)2D3], an active form of vitamin D, Wistar rats (14-week-old, male, 20 rats/group) were fed a powder diet containing 0 or 5 ppm 24R, 25(OH)2D3 for 57 wee
Autor:
Michihito Takahashi, Tomonori Enami, Hyoung-Chin Kim, Shinichiro Ikezaki, Akiyoshi Nishikawa, Fumio Furukawa, Shoji Fukushima, Zen-yo Tanakamaru
Publikováno v:
Journal of Toxicologic Pathology. 9:23-28
Suitable conditions of bleomycin (BLM)-treatment to effectively induce pulmonary fibrosis without high mortality were investigated in Syrian golden hamsters. Male 6-week-old hamsters were divided into 5 groups, each consisting of 5 animals. Groups 1-
Autor:
Zen-yo Tanakamaru, Ryoetsu Imai
Publikováno v:
Journal of Veterinary Medical Science. 55:367-370
To investigate age-related changes in visual function in rats, male and female Fischer 344 (F344) rats at 30 months of age were examined electrophysiologically and histopathologically. The selection rate for the dark area in a T-shaped test box was 8
Autor:
Zen-yo Tanakamaru
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 130(2)
Autor:
Makoto Ueda, Tamiko Adachi, Hiroyuki Ogasawara, Zen-yo Tanakamaru, Toshimi Usui, Shinya Sehata, Mamoru Mutai, Mikinori Torii, Takanori Maejima, Masaya Takaoka, Kaoru Toyosawa, Masahiro Matsumoto, Toshio Imai, Hiroshi Satoh, Kiyoshi Kobayashi, Shigeru Hisada
Publikováno v:
Toxicologic pathology. 31(2)
In order to evaluate a short-term carcinogenicity testing system using CB6F1-Tg rasH2 ( rasH2-Tg) mice carrying a human prototype c-Ha- ras gene, 26-week studies were conducted in 12 different facilities as a part of an International Life Science Ins
Autor:
Akiyoshi Nishikawa, Zen-yo Tanakamaru, Fumio Furukawa, Hideki Mori, Ikuo Mori, Michihito Takahashi
Publikováno v:
Cancer letters. 172(2)
Aberrant crypt foci (ACFs) in the Fischer 344 (F344) rat colon, of control or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-treated groups, were compared morphologically, immunohistochemically, and at the molecular biological level in order t