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Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in silico insights.

Autor: Hamdi, Abdelrahman¹ (AUTHOR) abdelrahmanhamdi2012@yahoo.com, Yaseen, Muhammad² (AUTHOR) muhammadyaseen.my907@gmail.com, Ewes, Wafaa A.¹ (AUTHOR), Bhat, Mashooq Ahmad³ (AUTHOR), Ziedan, Noha I.⁴ (AUTHOR), El-Shafey, Hamed W.¹ (AUTHOR), Mohamed, Ahmed A. B.⁵ (AUTHOR), Elnagar, Mohamed R.^6,7 (AUTHOR), Haikal, Abdullah⁸ (AUTHOR), Othman, Dina I. A.¹ (AUTHOR), Elgazar, Abdullah A.⁹ (AUTHOR), Abusabaa, Ahmed H. A.¹⁰ (AUTHOR), Abdelrahman, Kamal S.¹¹ (AUTHOR), Soltan, Osama M.¹¹ (AUTHOR), Elbadawi, Mostafa M.¹² (AUTHOR)

Publikováno v: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-12. 12p.

1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes.

Autor: Andrews KM; Pfizer Global Research and Development, Groton Laboratories, Groton, CT 06340, USA., Beebe DA, Benbow JW, Boyer DA, Doran SD, Hui Y, Liu S, McPherson RK, Neagu C, Parker JC, Piotrowski DW, Schneider SR, Treadway JL, VanVolkenberg MA, Zembrowski WJ

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2011 Mar 15; Vol. 21 (6), pp. 1810-4. Date of Electronic Publication: 2011 Jan 31.

The capable xanthine-based adsorbent for removal of the Cd(II), Ni(II) and Pb(II) ions from aqueous solution via their complexation and the use of its corresponding Cd complex for the green synthesis of indazolophthalazinetriones.

Autor: Ahmadi, Sharareh¹ (AUTHOR), Habibi, Davood¹ (AUTHOR) davood.habibi@gmail.com, Heydari, Somayyeh² (AUTHOR), Roshani Asl, Elmira² (AUTHOR)

Publikováno v: Research on Chemical Intermediates. Feb2023, Vol. 49 Issue 2, p763-789. 27p.