Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zelleka Getahun"'
Publikováno v:
Bulletin of the Chemical Society of Ethiopia, Vol 2, Iss 2, Pp 69-72 (1988)
Bull.Chem.Soc.Ethiop.,2(2), 69-72 (1988).
Externí odkaz:
https://doaj.org/article/5513ad7e60df4ce6a1b667ef1841c48e
Autor:
Zelleka Getahun, William F. DeGrado, Ting Wang, Deguo Du, Cheng-Yen Huang, Feng Gai, Yongjin Zhu
Publikováno v:
The Journal of Physical Chemistry B. 108:15301-15310
It is well-known that end caps and the peptide length can dramatically influence the thermodynamics of the helix–coil transition. However, their roles in determining the kinetics of the helix–coil transition have not been studied extensively and
Publikováno v:
Journal of the American Chemical Society. 125:405-411
It is well-known that the C=N stretching vibration in acetonitrile is sensitive to solvent. Therefore, we proposed in this contribution to use this vibrational mode to report local environment of a particular amino acid in proteins or local environme
Publikováno v:
Journal of the American Chemical Society. 123:9235-9238
The helix-coil transition of a synthetic alpha-helical peptide (the D-Arg peptide), Ac-YGG(KAAAA)(3)-CO-D-Arg-CONH(2), was studied by static far-UV circular dichroism (CD) and time-resolved infrared spectroscopy coupled with the laser-induced tempera
Publikováno v:
Journal of the American Chemical Society. 122:9883-9890
Infrared spectral frequencies of amide vibrational modes are sensitive to secondary structure. In this work, evidence is presented that accessibility to water additionally affects spectral positions. The dimeric α-helical coiled-coil GCN4-P1‘ was
Autor:
Patten Arthur David, R. J. Page, Margaret P. Stafford, R. J. Mcripley, M. R. Kirshenbaum, P. M. Czerniak, Robert J. Cherney, E. Akamike, Robert F. Kaltenbach, Mike Vavala, Zelleka Getahun, Steven P. Seitz, George L. Trainor, Stephen G. Swartz, Janet L. Gross, L. M. Papp, R. J. Diamond, Jung-Hui Sun, Carl Henry Behrens
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:163-168
Unsymmetrical bis-imides 1 were synthesized and evaluated as potential antitumor agents. These novel bis-imides were assessed using three criteria: in vitro cytotoxicity (L1210), in vitro DNA binding, and in vivo studies with human tumor xenografts i
Publikováno v:
Journal of Raman spectroscopy : JRS. 39(11)
The incorporation of unnatural amino acids into proteins that act as spectroscopic probes can be used to study protein structure and function. One such probe is 4-cyanophenylalanine (PheCN), the nitrile group of which has a stretching mode that occur
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 33:293-299
14C-Chloroacetates of 2-demethylthiocolchicine 7 (specific activity 55.0 mCi/mmol, radiochemical yield 26.1%), and of 3-demethylthiocolchicine 8 (specific activity 55.0 mCi/mmol, radiochemical yield 5.7%) were synthesized and found to covalently bind
Publikováno v:
ChemInform. 22
Autor:
Miles P. Hacker, Zelleka Getahun, A. P. Krapcho, K. L. Jun. Avery, S. Spinelli, G. Pezzoni, Carla Manzotti, K. J. Vargas
Publikováno v:
ChemInform. 22