Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zeljko Dzakula"'
Autor:
William Stedman, Han Cao, Michael Saghbini, Jason Bobe, Alex Hastie, David Catoe, Arend Sidow, Marc L. Salit, Kristina Giorda, Alexander Wait Zaranek, Stephen T. Sherry, Zeljko Dzakula, Gintaras Deikus, R Truty, Erich Jaeger, Alexa B. R. McIntyre, Karoline Bjarnesdatter Rypdal, Christopher C. Chang, Robert Sebra, Srinka Ghosh, Grace X.Y. Zheng, Jonathan Trow, Yuling Liu, Tiffany Y. Liang, Khoa Pham, Fiona Hyland, Heather Ordonez, Dhruva Chandramohan, Noah Spies, Ziming Weng, Sofia Kyriazopoulou-Panagiotopoulou, Yutao Fu, Eric E. Schadt, Lindsay K. Vang, Ali Bashir, Madeleine Ball, Christopher E. Mason, Preston W. Estep, Keyan Zhao, George M. Church, Justin M. Zook, Ying Sheng, Mark Chaisson, Patrick Marks, Natali Gulbahce, Elizabeth Henaff, Patrice A Mudivarti, Feng Chen, Jennifer McDaniel, Michael Schnall-Levin, Chunlin Xiao, Noah Alexander, Ali Moshrefi
Publikováno v:
Scientific Data
BMC Genomics
BMC Genomics
Background The human genome contains variants ranging in size from small single nucleotide polymorphisms (SNPs) to large structural variants (SVs). High-quality benchmark small variant calls for the pilot National Institute of Standards and Technolog
Publikováno v:
Clinical Chemistry. 58:1148-1151
BACKGROUND Efforts have been undertaken recently to assess the fetal genome through analysis of circulating cell-free (ccf) fetal DNA obtained from maternal plasma. Sequencing analysis of such ccf DNA has been shown to enable accurate prenatal detect
Autor:
Rajiv Bharadwaj, Bill Kengli Lin, Mohammad Rahimi, Zeljko Dzakula, Yifeng Yin, Tobias Daniel Wheeler, Kamila Belhocine, Sanjam Sawhney, Jon Sorenson, Andrew Price, Tony Makarewicz, Susana Jett, Katie Sullivan-Bibee, Claudia Catalanotti, Maengseok Song, Alaina Puleo, Michael Schnall-Levin, Viajy Kumar, Joe Shuga
Publikováno v:
Cancer Research. 78:3395-3395
The ability to sequence entire genomes at the level of single cells (SCs) is an essential tool for mapping heterogeneity in cancer. Knowledge of this variability provides insight into cancer dynamics and the efficacy of therapeutics. Copy number vari
Autor:
Kamila Belhocine, Deanna M. Church, Rajiv Bharadwaj, Andrew Price, Michael Schnall-Levin, Yifeng Yin, Sarah Garcia, Shamoni Maheshwar, Zeljko Dzakula, Sara Agee Le, Claudia Catalanotti, Vijay Kumar
Publikováno v:
Cancer Research. 78:3400-3400
Cancer genomes are highly unstable with new genetic variations emerging even within a single metastatic site, making it difficult to track the causal changes that drive metastasis and treatment resistance. Here we present a two-pronged approach for a
The 'CUPID' method for calculating the continuous probability distribution of rotamers from NMR data
Publikováno v:
Journal of the American Chemical Society. 114:6195-6199
We present a new method, ContinUous ProbabIlity Distribution of rotamers (CUPID), for determining the distribution of rotamer probability p(X) about a dihedral angle χ. This method utilizes measured vicinal homonuclear and heteronuclear spin-spin co
Publikováno v:
Journal of the American Chemical Society. 114:6200-6207
The theoretical foundations of CUPID, a new method for determining the rotamer probability distributions from NMR spin-spin coupling constants and NOE data, has been presented (Diakula, Z.; Westler, W. M.; Edison, A. S.; Markley, J. L. J. Am. Chem. S
Autor:
Thomas Anantharaman, Alex Hastie, E. Holmlin, H. Cao, Zeljko Dzakula, X. Xun, Andy Wing Chun Pang, Pui-Yan Kwok, M. Austin, M. Saghbini, T. Chan, W. Andrews, H. Sadoski, Michael R. Rossi, T. Dickinson
Publikováno v:
Cancer Research. 75:4746-4746
In spite of advancements in high-throughput short read next-generation sequencing in the past decade, the majority of genome analysis today is limited in exome or transcriptome sequencing, leaving a fair portion of the human genome unresolved or ambi
Publikováno v:
Journal of Biomolecular NMR. 12:193-195
Autor:
Ernest T. Lam, Han Cao, Andy Wing Chun Pang, Xing Yang, Michael R. Rossi, Xun Xu, Heng Dai, Pui Kwok, Todd Dickinson, Henry Sadoski, Alex Hastie, Michael Saghbini, Thomas Anantharaman, Michael J Austin, Warren Andrews, Zeljko Dzakula
Publikováno v:
Blood. 124:476-476
Diseases with complex traits such as hematological cancer are known to be associated with large structural variations (SV > 1 kb). Techniques such as karyotyping, FISH and aCGH have been common tools for gross chromosomal lesion analysis. Yet populat
Publikováno v:
Journal of the American Chemical Society. 114:9727-9727