Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Zeljka Brkic"'
Autor:
Marina Zaric Kontic, Milorad Dragic, Jelena Martinovic, Katarina Mihajlovic, Zeljka Brkic, Natasa Mitrovic, Ivana Grkovic
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 331 (2023)
Alprazolam (ALP), a benzodiazepine (BDZ) used to treat anxiety, panic, and sleep disorders, is one of the most prescribed psychotropic drugs worldwide. The side effects associated with long-term (mis)use of ALP have become a major challenge in pharma
Externí odkaz:
https://doaj.org/article/e59211b18e784180aef55a63b5fe2af6
Autor:
Željka Brkić, Ozren Larva
Publikováno v:
Journal of Hydrology: Regional Studies, Vol 54, Iss , Pp 101858- (2024)
Study region: The case study presents Vrana Lake on Cres island in Croatia, which is the largest freshwater resource on the Mediterranean islands. It is used for the public water supply of the residents and tourists who inhabit this island during the
Externí odkaz:
https://doaj.org/article/b0fef0287b5d4cf2ac34893a7b7f254f
Publikováno v:
Journal of Neuroscience Research
Adolescent stress predisposes individuals to increased risk for anxiety and depression in adulthood. The stress response is mediated by the glucocorticoid receptor (GR) via regulation of GR-responsive genes involved in brain reaction to stress. Altho
Autor:
Milos Mitic, Jelena Radulovic, Zorica Petrovic, Iva Lukic, Zeljka Brkic, Miroslav Adzic, Ester Francija
Publikováno v:
Behav Brain Res
Behavioural Brain Research
Behavioural Brain Research
Inflammation plays a key role in the pathogenesis of the major depressive disorder. Namely, neuroinflammation can induce the production of neuroactive metabolites that interfere with N-methyl-D-aspartate receptors (NMDAR)-mediated glutamatergic neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360c067f78dc1f360bdf41db4f4345c6
https://europepmc.org/articles/PMC9878822/
https://europepmc.org/articles/PMC9878822/
Autor:
Miroslav Adzic, Ivan Soldatovic, Milos Mitic, Zorana Pavlovic, Marina Mihaljevic, Milica J Nesic, Zorica Petrovic, Zeljka Brkic, Jelena Radulovic, Minja Milosavljevic, Emilija Glavonic, Nadja P. Maric, Ester Francija
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Childhood trauma (CT) increases the risk for psychopathology through disturbed acquisition and extinction of fear. The effects of CT are mediated by abnormalities of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor (GR). Since, the
Publikováno v:
Neuroscience
Mitochondria play a significant role in pathogenesis of clinical depression and their function can be impaired by inflammation and alterations in hypothalamic–pituitary–adrenal axis. Sexual context is also a relevant factor in the incidence of mo
Publikováno v:
Behavioural Brain Research
Accumulating evidence strongly suggest that impaired glucocorticoid receptor (GR) signaling is involved in stress-related mood disorders, and nominate GR as a potential target for antidepressants (ADs). It is known that different classes of ADs affec
Publikováno v:
Brain Research Bulletin
Mitochondrial dysfunction can result from the interplay between elevated inflammatory markers and alterations in hypothalamic–pituitary–adrenal (HPA) axis, and can contribute to pathogenesis of major depression. Therefore, in this study we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b7ebf0230153d7fa5a8fa183ec4ec7
https://vinar.vin.bg.ac.rs/handle/123456789/8359
https://vinar.vin.bg.ac.rs/handle/123456789/8359
Publikováno v:
Behavioural Brain Research
Recent reports have demonstrated that lipopolysaccharide (LPS)-induced depressive-like behaviour is mediated via NMDA receptor. In this study, we further investigated the role of GluN2 A subunit of NMDA receptor in synaptic processes in the prefronta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e747fa65c497522b81ad60f1e0b0ac
https://vinar.vin.bg.ac.rs/handle/123456789/8450
https://vinar.vin.bg.ac.rs/handle/123456789/8450
Publikováno v:
Drug Development Research. 77:400-406
Preclinical Research Mitochondria are cell organelles crucial to the production of cellular energy. Several lines of evidence have indicated that mitochondrial dysfunction could be related to the pathophysiology of CNS diseases including bipolar diso