Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Zeling Niu"'
Publikováno v:
The Journal of Bone and Joint Surgery-American Volume. 85:29-33
Background: Chondrocyte maturation and hypertrophy during endochondral bone formation are stimulated by both retinoids and bone morphogenetic proteins (BMPs). The type-X collagen gene, which is expressed only in hypertrophic chondrocytes, provides an
Autor:
Janine Trindade, Zeling Niu, Paul C. Billings, Sherrill L. Adams, T.R. Lakshmi, Arthur J. Cohen
Publikováno v:
Mechanisms of Development. 114:177-180
We have identified a noncollagenous protein, Col3alt, encoded by an alternative transcript of the chick type III collagen gene; its amino acid sequence is out of frame with the collagen coding sequence. This 178-amino-acid protein is unique and has n
Publikováno v:
Developmental Dynamics. 206:146-158
Endochondral bone formation is characterized by several transitions in the pattern of collagen gene expression, the best characterized of which occurs during chondrogenesis. Prechondrogenic mesenchymal cells synthesize predominantly type I collagen;
An alternative transcript of the chick type III collagen gene that does not encode type III collagen
Publikováno v:
Journal of Biological Chemistry. 269:16443-16448
Type III collagen, a ubiquitous protein found in most connective tissues, is not present in hyaline cartilage. However, we have identified an alternative transcript of the type III collagen gene in cultured chondrocytes from several embryonic chick c
Publikováno v:
Journal of cellular biochemistry. 99(1)
Retinoids are essential for the terminal differentiation of chondrocytes during endochondral bone formation. This maturation process is characterized by increased cell size, expression of a unique extracellular matrix protein, collagen X, and eventua
Publikováno v:
The Penn dental journal. 102
Publikováno v:
Nucleic acids research. 27(20)
The chick type III collagen gene contains an internal promoter in intron 23 in addition to the promoter preceding exon 1. The internal promoter, which is used preferentially in cultured chondrocytes, directs production of an alternative transcript th
Type III collagen is present in prechondrogenic mesenchyme, but not in cartilages formed during endochondral ossification. However, cultured chick chondrocytes contain an unusual transcript of the type III collagen gene in which exons 1-23 are replac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c14a96d946b10d32c428eadbaa0fa3
https://europepmc.org/articles/PMC146743/
https://europepmc.org/articles/PMC146743/
Publikováno v:
The Journal of biological chemistry. 271(41)
Embryonic chick cartilages contain transcripts derived from the alpha2(I) collagen gene, although type I collagen is not normally found in these tissues; most of these RNAs are alternative transcripts initiating within intron 2. Use of the internal s
Autor:
Eleanor B. Golden, Kim M. Pallante, Phoebe S. Leboy, Sherrill L. Adams, Maurizio Pacifici, Zeling Niu
Publikováno v:
Experimental cell research. 193(1)
During endochondral ossification, small rapidly proliferating chondrocytes mature into flattened discshaped cells and then into large round hypertrophic cells. These morphological changes are accompanied by a decrease in the rate of cell proliferatio