Retinal Ganglion Cell Protection Via Topical and Systemic Alpha-Tocopherol Administration in Optic Nerve Crush Model of Rat

Autor: Zeynep Aktaş, Cüneyt Özmen, Pinar Göçün, Zelihagül Değim, Yeşim Özkan, Merih Onol

Publikováno v: Türk Oftalmoloji Dergisi, Vol 43, Iss 3, Pp 161-166 (2013)

Pur po se: The aim of our study was to investigate the neuroprotective effects of topical α-tocopherol in optic nerve crush model of rat and to compare its efficacy with that of systemic α -tocopherol. Ma te ri al and Met hod: 50 eyes of 25 Wista

Externí odkaz: https://doaj.org/article/6c09e4d1d6f142a0989fb2b8a2857b3b

Development and validation of highly selective method for the determination of imatinib mesylate and dexketoprofen trometamol combination in three different media

Autor: Özlem Çoban, Zelihagül Değim

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020)
Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e18583
Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e18583
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e18583, Published: 18 SEP 2020

Imatinib mesylate is a small molecule used in cancer therapy as a thyrosine kinase inhibitor. Dexketoprofen trometamol is a non-steroidal anti-inflammatory drug that has seen use in cancer therapy in combination with an anticancer drug to minimize tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35915ffafcfe35b8514c404fb66e985
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100575&tlng=en

Formation of quantum water in nanoparticulate systems

Autor: Firat Yerlikaya, Gamze Camlik, Eduardo Sobarzo-Sánchez, İsmail Tuncer Değim, Zelihagül Değim, Esra Küpeli Akkol

Publikováno v: Journal of Drug Delivery Science and Technology. 63:102456

The development or designing of new and futuristic drug delivery systems have been mainly focused on nanoparticles and the drug, but the alteration of water properties or configuration of water molecules in these formulations have not been properly a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dde79c2d1e41cc95f448f2fb46adb2
https://doi.org/10.1016/j.jddst.2021.102456

Development of Cisplatin-loaded Liposome and Evaluation of Transport Properties Through Caco-2 Cell Line

Autor: Zelihagül Değim, Şükran Yılmaz, Çiğdem Yücel

Publikováno v: Turkish Journal of Pharmaceutical Sciences, Vol 13, Iss 1, Pp 69-80 (2016)

Cisplatin is a potent anticancer drug for treating tumors, that has long been widely used. The therapeutic exploitation of cisplatin is limited by its toxicity toward healthy tissues. Liposomes can provide enhanced efficacy and/or reduced toxicity an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e679d17c140d872e11e4da21090913
https://doi.org/10.5505/tjps.2016.32032

Effects of insulin and embryonic stem cells loaded plga nanoparticles on pancreatic beta tc cells

Autor: Mahmut Sözmen, Şükran Yılmaz, Çiğdem Yücel, Yeşim Aktaş, Taibe Arsoy, Levent Altintas, Zelihagül Değim, Can Çokçalışkan

This work was carried out at the Faculty of Pharmacy of Gazi University as a PhD thesis and supported by the Scientific and Technological Research Council of Turkey (TUBYTAK, No. 112S405).
The present study, aims to investigate and compare the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb6ea39bd33d74955e4b3e22a20d82b
https://hdl.handle.net/20.500.12445/647