Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zeliha, Ozgur"'
Autor:
Ileana Cantú, Harmen J G van de Werken, Nynke Gillemans, Ralph Stadhouders, Steven Heshusius, Alex Maas, Fatemehsadat Esteghamat, Zeliha Ozgur, Wilfred F J van IJcken, Frank Grosveld, Marieke von Lindern, Sjaak Philipsen, Thamar B van Dijk
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >140 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://doaj.org/article/a036d268167f4395a300831947ef3990
Autor:
Ayestha Sijm, Yaser Atlasi, Jan A. van der Knaap, Joyce Wolf van der Meer, Gillian E. Chalkley, Karel Bezstarosti, Dick H. W. Dekkers, Wouter A. S. Doff, Zeliha Ozgur, Wilfred F. J. van IJcken, Jeroen A. A. Demmers, C. Peter Verrijzer
Publikováno v:
Science advances, 8(44):abq7598. American Association for the Advancement of Science
Sijm, A, Atlasi, Y, van der Knaap, J A, van der Meer, J W, Chalkley, G E, Bezstarosti, K, Dekkers, D H W, Doff, W A S, Ozgur, Z, van IJcken, W F J, Demmers, J A A & Verrijzer, C P 2022, ' USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3 ', Science Advances, vol. 8, no. 44, abq7598 . https://doi.org/10.1126/sciadv.abq7598
Sijm, A, Atlasi, Y, van der Knaap, J A, van der Meer, J W, Chalkley, G E, Bezstarosti, K, Dekkers, D H W, Doff, W A S, Ozgur, Z, van IJcken, W F J, Demmers, J A A & Verrijzer, C P 2022, ' USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3 ', Science Advances, vol. 8, no. 44, abq7598 . https://doi.org/10.1126/sciadv.abq7598
Ubiquitin-specific protease 7 (USP7) has been implicated in cancer progression and neurodevelopment. However, its molecular targets remain poorly characterized. We combined quantitative proteomics, transcriptomics, and epigenomics to define the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8154b759994b52753de3c189ce8b3ce3
https://pubmed.ncbi.nlm.nih.gov/36332031
https://pubmed.ncbi.nlm.nih.gov/36332031
Autor:
Joachim Boers, Frank Sleutels, Enrique Vidal, Rainer Renkawitz, Frank Grosveld, Ruben Boers, Niels Galjart, Mirjam C G N van den Hout, Silvia C Hernandez, Wiggert A. van Cappellen, Sarra Merzouk, Adriaan B Houtsmuller, Gregoire Stik, Marek Bartkuhn, Michael van der Reijden, Joost Gribnau, Thomas Graf, Zeliha Ozgur, Sreya Basu, Ralph Stadhouders, Widia Soochit, Bart Geverts, Wilfred F. J. van IJcken
Publikováno v:
Dev Cell
Nature Cell Biology, 23(8), 881-893. Nature Publishing Group
Nature Cell Biology, 23(8), 881-893. Nature Publishing Group
The 11 zinc finger (ZF) protein CTCF regulates topologically associating domain formation and transcription through selective binding to thousands of genomic sites. Here, we replaced endogenous CTCF in mouse embryonic stem cells with green-fluorescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dfc5062424a1bb8d40df0bdfc26739
https://doi.org/10.1038/s41556-021-00722-w
https://doi.org/10.1038/s41556-021-00722-w
Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A.
Autor:
Yuri M Moshkin, Cecile M Doyen, Tsung-Wai Kan, Gillian E Chalkley, Karen Sap, Karel Bezstarosti, Jeroen A Demmers, Zeliha Ozgur, Wilfred F J van Ijcken, C Peter Verrijzer
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003719 (2013)
Chromosome duplication and transmission into daughter cells requires the precisely orchestrated binding and release of cohesin. We found that the Drosophila histone chaperone NAP1 is required for cohesin release and sister chromatid resolution during
Externí odkaz:
https://doaj.org/article/f226f498ab2b493f9b3fe949caa4c2de
Autor:
Bas de Hoon, Anco Molijn, Christel E M Kockx, Wilfred F. J. van IJcken, Ruben Boers, Joop S.E. Laven, Zeliha Ozgur, Joost Gribnau, Joachim Boers
Publikováno v:
Genome Research, 28(1), 88-99. Cold Spring Harbor Laboratory Press
DNA methylation is a well-known epigenetic modification that plays a crucial role in gene regulation, but genome-wide analysis of DNA methylation remains technically challenging and costly. DNA methylation-dependent restriction enzymes can be used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0811524767b3e730966e53db0dcb54d0
https://doi.org/10.1101/gr.222885.117
https://doi.org/10.1101/gr.222885.117
Autor:
Steven Heshusius, Frank Grosveld, Ralph Stadhouders, Marieke von Lindern, Sjaak Philipsen, Alex Maas, Nynke Gillemans, Wilfred F. J. van IJcken, Harmen J.G. van de Werken, Thamar B. van Dijk, Zeliha Ozgur, Fatemehsadat Esteghamat, Ileana Cantú
Publikováno v:
PLoS ONE
PLoS ONE, 14(3):e0208659. Public Library of Science
PLoS One (online), 14(3):e0208659. Public Library of Science
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
PLoS ONE, 14(3):e0208659. Public Library of Science
PLoS One (online), 14(3):e0208659. Public Library of Science
PLoS ONE, Vol 14, Iss 3, p e0208659 (2019)
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >140 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492dd1d517b628ed98595503933f7fd9
http://europepmc.org/articles/PMC6438607
http://europepmc.org/articles/PMC6438607
Autor:
Robert M.W. Hofstra, Matej Skorvanek, Zeliha Ozgur, Vincenzo Bonifati, Kees Schoonderwoerd, Simone Olgiati, Robert Jech, Frans W. Verheijen, Mirjam C G N van den Hout, Michelle Minneboo, Josja Graafland, Wim Mandemakers, Zuzana Gdovinova, Szu Chia Lai, Vladimir Han, Hsiu Chen Chang, Hsin Fen Chien, Ramon Bonte, Guido J. Breedveld, Tu Hsueh Yeh, Wilfred F. J. van IJcken, Marialuisa Quadri, Anneke J.A. Kievit, Egberto Reis Barbosa, Yah Huei Wu-Chou, George J. G. Ruijter, Chin Song Lu
Publikováno v:
Movement Disorders. 31:1041-1048
Background ECHS1 encodes a mitochondrial enzyme involved in the degradation of essential amino acids and fatty acids. Recently, ECHS1 mutations were shown to cause a new severe metabolic disorder presenting as Leigh or Leigh-like syndromes. The objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b60ca1c184bdda6722bf239289a87b
https://doi.org/10.1002/mds.26610
https://doi.org/10.1002/mds.26610
Autor:
Marieke von Lindern, Ralph Stadhouders, Steven Heshusius, Frank Grosveld, Sjaak Philipsen, Wilfred F. J. van IJcken, Alex Maas, Zeliha Ozgur, Thamar B. van Dijk, Harmen J.G. van de Werken, Ileana Cantú, Nynke Gillemans
Krüppel-like factor 1 (KLF1) is an essential transcription factor for erythroid development, as demonstrated by Klf1 knockout mice which die around E14 due to severe anemia. In humans, >65 KLF1 variants, causing different erythroid phenotypes, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eaadd8624adc3d435bffacfe0a38f1
Autor:
Raymond A. Poot, Mike R. Dekker, Johannes H. Brandsma, Wilfred F. J. van IJcken, Debbie L. C. van den Berg, Dick H. W. Dekkers, Maarten Fornerod, Jeroen Demmers, Zeliha Ozgur, Lize Meert, Marti Quevedo
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, 10:2669. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, 10:2669. Nature Publishing Group
The Mediator complex regulates transcription by connecting enhancers to promoters. High Mediator binding density defines super enhancers, which regulate cell-identity genes and oncogenes. Protein interactions of Mediator may explain its role in these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac69087419bfe4720c9d4a11d3cea30b
https://pubmed.ncbi.nlm.nih.gov/31332183
https://pubmed.ncbi.nlm.nih.gov/31332183
Autor:
Wenda Verschoor, Zeliha Ozgur, Karin Boer, Nicolle H.R. Litjens, J.M. Zuijderwijk, Mirjam C G N van den Hout-van Vroonhoven, Annemiek M.A. Peeters, Rens Kraaijeveld, Michiel G. H. Betjes, Wilfred F. J. van IJcken, Mariska Klepper, Carla C. Baan, Errol P. Prens
Publikováno v:
Journal of Immunology, 194(11), 5282-5293. American Association of Immunologists
Expansion of Ag-specific naturally occurring regulatory T cells (nTregs) is required to obtain sufficient numbers of cells for cellular immunotherapy. In this study, different allogeneic stimuli were studied for their capacity to generate functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b048a7b22294a6d30f469594057a1640
https://doi.org/10.4049/jimmunol.1402827
https://doi.org/10.4049/jimmunol.1402827