Cytogenomic epileptology.

Autor: Iourov IY; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia. ivan.iourov@gmail.com.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia. ivan.iourov@gmail.com.; Department of Medical Biological Disciplines, Belgorod State University, Belgorod, Russia. ivan.iourov@gmail.com., Gerasimov AP; Research Laboratory of Pediatric Neurosurgery, Polenov Neurosurgical Institute, Almazov National Medical Research Centre, Saint Petersburg, Russia., Zelenova MA; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Ivanova NE; Scientific Department of Polenov Neurosurgical Institute, Almazov National Medical Research Centre, Saint Petersburg, Russia., Kurinnaia OS; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Zabrodskaya YM; Research Laboratory of Pathomorphology of the Nervous System, Almazov National Medical Research Centre, Saint Petersburg, Russia., Demidova IA; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Barantsevich ER; Postgraduate Neurology and Manual Medicine Department, Pavlov First Saint-Petersburg State Medical University, Saint Petersburg, Russia., Vasin KS; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Kolotii AD; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Ushanov VV; Department of Neurosurgery, Almazov National Medical Research Centre, Saint Petersburg, Russia., Sitovskaya DA; Research Laboratory of Pathomorphology of the Nervous System, Almazov National Medical Research Centre, Saint Petersburg, Russia., Lobzhanidze TB; Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia., Iuditskaia ME; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Iakushev NS; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Zhumatov MM; Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia., Vorsanova SG; Yurov's Laboratory of Molecular Genetics and Cytogenomics of the Brain, Mental Health Research Center, Moscow, Russia.; Vorsanova's Laboratory of Molecular Cytogenetics of Neuropsychiatric Diseases, Veltischev Research and Clinical Institute for Pediatrics and Pediatric Surgery of the Pirogov Russian National Research Medical University of the Russian Ministry of Health, Moscow, Russia., Samochernyh KA; Polenov Neurosurgical Institute, Almazov National Medical Research Centre, Saint Petersburg, Russia.

Publikováno v: Molecular cytogenetics [Mol Cytogenet] 2023 Jan 05; Vol. 16 (1), pp. 1. Date of Electronic Publication: 2023 Jan 05.

The Cytogenomic "Theory of Everything": Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and Aging.

Autor: Iourov IY; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia.; Department of Medical Biological Disciplines, Belgorod State University, 308015 Belgorod, Russia., Vorsanova SG; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Yurov YB; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Zelenova MA; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Kurinnaia OS; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Vasin KS; Mental Health Research Center, 117152 Moscow, Russia.; Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Kutsev SI; Research Centre for Medical Genetics, 115522 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Nov 06; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 06.

[Epigenomic variations manifesting as a loss of heterozygosity affecting imprinted genes represent a molecular mechanism of autism spectrum disorders and intellectual disability in children].

Autor: Iourov IY; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia; Russian Medical Academy for Postgraduate Continuing Education, Moscow, Russia., Vorsanova SG; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia., Zelenova MA; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia., Vasin KS; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia., Kurinnaia OS; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia., Korostelev SA; Sechenov First Moscow State Medical University, Moscow, Russia., Yurov YB; Mental Health Research Center, Moscow, Russia; Veltishchev Research Clinical Institute of Pediatric of Pirogov Russian National Research Medical University, Moscow, Russia.

Publikováno v: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2019; Vol. 119 (5), pp. 91-97.

4q21.2q21.3 Duplication: Molecular and Neuropsychological Aspects.

Autor: Iourov IY; Mental Health Research Center, Moscow, Russian Federation.; Separated Structural Unit 'Clinical Research Institute of Pediatrics named after Y.E Veltishev', Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russian Federation.; Department of Medical Genetics, Russian Medical Academy of Postgraduate Education, Ministry of Health, Moscow, Russian Federation., Zelenova MA; Mental Health Research Center, Moscow, Russian Federation.; Separated Structural Unit 'Clinical Research Institute of Pediatrics named after Y.E Veltishev', Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russian Federation.; Moscow State University of Psychology and Education, Moscow, Russian Federation., Vorsanova SG; Mental Health Research Center, Moscow, Russian Federation.; Separated Structural Unit 'Clinical Research Institute of Pediatrics named after Y.E Veltishev', Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russian Federation.; Moscow State University of Psychology and Education, Moscow, Russian Federation., Voinova VV; Mental Health Research Center, Moscow, Russian Federation.; Separated Structural Unit 'Clinical Research Institute of Pediatrics named after Y.E Veltishev', Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russian Federation.; Moscow State University of Psychology and Education, Moscow, Russian Federation., Yurov YB; Mental Health Research Center, Moscow, Russian Federation.; Separated Structural Unit 'Clinical Research Institute of Pediatrics named after Y.E Veltishev', Pirogov Russian National Research Medical University, Ministry of Health, Moscow, Russian Federation.; Moscow State University of Psychology and Education, Moscow, Russian Federation.

Publikováno v: Current genomics [Curr Genomics] 2018 Apr; Vol. 19 (3), pp. 173-178.

Long contiguous stretches of homozygosity spanning shortly the imprinted loci are associated with intellectual disability, autism and/or epilepsy.

Autor: Iourov IY; Mental Health Research Center, 117152 Moscow, Russia ; Separated Structural Unit 'Clinical Research Institute of Pediatrics', Russian National Research Medical University named after N.I. Pirogov, Ministry of Health of Russian Federation, 125412 Moscow, Russia ; Department of Medical Genetics, Russian Medical Academy of Postgraduate Education, 123995 Moscow, Russia., Vorsanova SG; Mental Health Research Center, 117152 Moscow, Russia ; Separated Structural Unit 'Clinical Research Institute of Pediatrics', Russian National Research Medical University named after N.I. Pirogov, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Korostelev SA; Research Centre for Medical Genetics, 115478 Moscow, Russia., Zelenova MA; Mental Health Research Center, 117152 Moscow, Russia ; Separated Structural Unit 'Clinical Research Institute of Pediatrics', Russian National Research Medical University named after N.I. Pirogov, Ministry of Health of Russian Federation, 125412 Moscow, Russia., Yurov YB; Mental Health Research Center, 117152 Moscow, Russia ; Separated Structural Unit 'Clinical Research Institute of Pediatrics', Russian National Research Medical University named after N.I. Pirogov, Ministry of Health of Russian Federation, 125412 Moscow, Russia.

Publikováno v: Molecular cytogenetics [Mol Cytogenet] 2015 Oct 15; Vol. 8, pp. 77. Date of Electronic Publication: 2015 Oct 15 (Print Publication: 2015).