Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zelalem Ayenew Worku"'
Publikováno v:
Pharmaceutics
Volume 12
Issue 5
Pharmaceutics, Vol 12, Iss 433, p 433 (2020)
Volume 12
Issue 5
Pharmaceutics, Vol 12, Iss 433, p 433 (2020)
When developing an amorphous solid dispersion (ASD), a prudent choice of polymer is critical to several aspects of ASD performance including: processability, solid state stability and dissolution rate. However, there is little guidance available to f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b435aea196044a0a41d21ddd0649f9
Autor:
Vamsi Krishna Kamaraju, Brian Glennon, Dinesh Kumar, Yuan Gao, Ramesh Babu, Zelalem Ayenew Worku, Anne Marie Healy
Publikováno v:
Powder Technology. 330:228-238
Understanding the differences between wet milling (WM) and the dry milling (DM) is crucial in selecting the methodology used in pharmaceutical milling processes. This research examined WM and DM processes for ibuprofen (IBU), a Biopharmaceutics Class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1afeb0294574f96890c9a662558dc6cd
https://doi.org/10.1016/j.powtec.2018.02.022
https://doi.org/10.1016/j.powtec.2018.02.022
Autor:
Francisco Bolás-Fernández, María Auxiliadora Dea-Ayuela, Peter O'Connell, Anne Marie Healy, Zelalem Ayenew Worku, David P. Walsh, Naila A. Mugheirbi, Carolina Galiana, Dolores R. Serrano
Publikováno v:
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
Fundación Universitaria San Pablo CEU (FUSPCEU)
En European Journal of Pharmaceutics and Biopharmaceutics. Amsterdam (Países Bajos) : Elsevier. Vol. 124 (march 2018), pp. 13-27. ISSN 0939-6411. e-ISSN 1873-3441. Este artículo se encuentra disponible en la página web de la revista en la siguient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0407a7add0450779714adac4c618c640
https://doi.org/10.1016/j.ejpb.2017.11.015
https://doi.org/10.1016/j.ejpb.2017.11.015
Publikováno v:
International Journal of Pharmaceutics. 536:467-477
Spray drying is a well-established scale-up technique for the production of cocrystals. However, to the best of our knowledge, the effect of introducing a third component into the feed solution during the spray drying process has never been investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9829a683db33e6793ef75a9338d79f
https://doi.org/10.1016/j.ijpharm.2017.12.020
https://doi.org/10.1016/j.ijpharm.2017.12.020
Autor:
Raghu V. G. Peddapatla, Abina M. Crean, Shrikant Swaminathan, Conor Slevin, Gerard Sheridan, Zelalem Ayenew Worku, Ivan Browning, Stephen Sheehan, Clare O’Reilly, David Egan
Publikováno v:
Pharmaceutics, Vol 13, Iss 1033, p 1033 (2021)
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics
Volume 13
Issue 7
Optimizing processing conditions to achieve a critical quality attribute (CQA) is an integral part of pharmaceutical quality by design (QbD). It identifies combinations of material and processing parameters ensuring that processing conditions achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67979649a61200f60a9172c62d144ff8
https://doi.org/10.3390/pharmaceutics13071033
https://doi.org/10.3390/pharmaceutics13071033
Autor:
Peter O'Connell, Zelalem Ayenew Worku, Yunliang He, Åke C. Rasmuson, Brian Glennon, Kiran A. Ramisetty, João Victor Teixeira Gomes, Dinesh Kumar, Anne Marie Healy, Nalini R. Shastri, Kieran H. Gallagher, Trevor Woods
Publikováno v:
International Journal of Pharmaceutics. 531:191-204
peer-reviewed The development of solid dosage forms and manufacturing processes are governed by complex physical properties of the powder and the type of pharmaceutical unit operation the manufacturing processes employs. Suitable powder flow properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd07a2a35d9bb77a68f9f08c1f54c884
https://doi.org/10.1016/j.ijpharm.2017.08.063
https://doi.org/10.1016/j.ijpharm.2017.08.063
Publikováno v:
International journal of pharmaceutics. 566
The purpose of this work was to compare the particle characteristics and dissolution performance of amorphous solid dispersions (ASDs) of ketoprofen and vinyl-pyrrolidone based polymers prepared using electrospraying and spray drying methods. Solutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948fdfdf2a73ffa942d3f23820b59285
https://pubmed.ncbi.nlm.nih.gov/31132449
https://pubmed.ncbi.nlm.nih.gov/31132449
Autor:
Anne Marie Healy, Zelalem Ayenew Worku, Enrique Morales, Nicoletta Donato, Dolores R. Serrano, Antonio Matji, Juan J. Torrado, Adrianna Gagol, Luis Enrique Otero Carvajal
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Roller compaction is a low cost granulation process which application is sometimes limited by the granular loss of compactability and reduced drug dissolution rate. Hence, the design of a robust manufacturing process is key in order to ensure quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e58c56fd488ce3fa48bacf50487c393
https://pubmed.ncbi.nlm.nih.gov/31075438
https://pubmed.ncbi.nlm.nih.gov/31075438
Publikováno v:
AAPS PharmSciTech. 20
Different pharmaceutical manufacturing processes have been demonstrated to represent feasible platforms for the production of pharmaceutical cocrystals. However, new methods are needed for the manufacture of cocrystals on a large scale. In this work,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905266f83319b2769c9640687f8701d4
https://doi.org/10.1208/s12249-018-1228-4
https://doi.org/10.1208/s12249-018-1228-4
Autor:
Anne Marie Healy, David P. Walsh, Brendan Twamley, Atif Madi, Dolores R. Serrano, Zelalem Ayenew Worku, Peter O'Connell
Publikováno v:
International journal of pharmaceutics. 551(1-2)
The comparison of spray drying versus hot melt extrusion (HME) in order to formulate amorphous solid dispersions has been widely studied. However, to the best of our knowledge, the use of both techniques to form cocrystals within a carrier excipient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed94f44a92a803c7b248584669553ea0
https://pubmed.ncbi.nlm.nih.gov/30223079
https://pubmed.ncbi.nlm.nih.gov/30223079